Synthesis and antimycobacterial activity of disubstituted benzyltriazoles

Novel Synthetic Polyamines Have Potent Antimalarial Activities in vitro and in vivo by Decreasing Intracellular Spermidine and Spermine Concentrations

(2019) Kamal El Bissati et al.   Frontiers in Cellular and Infection Microbiology

Discovery of (3-Benzyl-5-hydroxyphenyl)carbamates as New Antitubercular Agents with Potent In Vitro and In Vivo Efficacy

(2019) Ya-Juan Cheng et al.   MOLECULES

Fluoroquinolone derivatives and their anti-tubercular activities

(2018) Yi-Lei Fan et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, synthesis, and biological evaluation of m-amidophenol derivatives as a new class of antitubercular agents

(2018) Niu-niu Zhang et al.   MedChemComm

Challenging the Drug-Likeness Dogma for New Drug Discovery in Tuberculosis

(2018) Diana Machado et al.   Frontiers in Microbiology

Mutations inside rifampicin-resistance determining region of rpoB gene associated with rifampicin-resistance in Mycobacterium tuberculosis

(2018) Myo T. Zaw et al.   Journal of Infection and Public Health

Acyloxybenzyl and Alkoxyalkyl Prodrugs of a Fosmidomycin Surrogate as Antimalarial and Antitubercular Agents

(2018) Charlotte Courtens et al.   ACS Medicinal Chemistry Letters

Optimization of N-benzyl-5-nitrofuran-2-carboxamide as an antitubercular agent

(2018) Ricardo Gallardo-Macias et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

4-Aminoquinoline-ferrocenyl-chalcone conjugates: Synthesis and anti-plasmodial evaluation

(2017) Amandeep Singh et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Triazole derivatives and their anti-tubercular activity

(2017) Shu Zhang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Green Synthesis of Potential Antifungal Agents: 2-Benzyl Substituted Thiobenzoazoles

(2017) María Sol Ballari et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Novel Antitubercular 6-Dialkylaminopyrimidine Carboxamides from Phenotypic Whole-Cell High Throughput Screening of a SoftFocus Library: Structure–Activity Relationship and Target Identification Studies

(2017) Colin R. Wilson et al.   JOURNAL OF MEDICINAL CHEMISTRY

The Benzyl Moiety in a Quinoxaline-Based Scaffold Acts as a DNA Intercalation Switch

(2016) Tridib Mahata et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

1,2,3-Triazoles as Amide Bioisosteres: Discovery of a New Class of Potent HIV-1 Vif Antagonists

(2016) Idrees Mohammed et al.   JOURNAL OF MEDICINAL CHEMISTRY

Aminopyrazolo[1,5- a ]pyrimidines as potential inhibitors of Mycobacterium tuberculosis : Structure activity relationships and ADME characterization

(2015) Candice Soares de Melo et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Applications of Fluorine in Medicinal Chemistry

(2015) Eric P. Gillis et al.   JOURNAL OF MEDICINAL CHEMISTRY

Hit and lead criteria in drug discovery for infectious diseases of the developing world

(2015) Kei Katsuno et al.   NATURE REVIEWS DRUG DISCOVERY

Synthesis and antifungal activity of 1,2,3-triazole phenylhydrazone derivatives

(2015) Zhi-Cheng Dai et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Genetic Mutations Associated with Isoniazid Resistance in Mycobacterium tuberculosis: A Systematic Review

(2015) Marva Seifert et al.   PLoS One

Are 1,4- and 1,5-Disubstituted 1,2,3-Triazoles Good Pharmacophoric Groups?

(2014) Alberto Massarotti et al.   ChemMedChem

Synthesis of novel 1,2,3-triazole derivatives of isoniazid and their in vitro and in vivo antimycobacterial activity evaluation

(2014) Deepak Kumar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

1H-1,2,3-triazole tethered isatin-ferrocene conjugates: Synthesis and in vitro antimalarial evaluation

(2014) Kewal Kumar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and evaluation of 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(4-(2-(4-substitutedpiperazin-1-yl)acetyl)piperazin-1-yl)quinoline-3-carboxylic acid derivatives as anti-tubercular and antibacterial agents

(2013) Narva Suresh et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

A Dual Read-Out Assay to Evaluate the Potency of Compounds Active against Mycobacterium tuberculosis

(2013) Juliane Ollinger et al.   PLoS One

Pathway-Selective Sensitization of Mycobacterium tuberculosis for Target-Based Whole-Cell Screening

(2012) Garth L. Abrahams et al.   CHEMISTRY & BIOLOGY

Synthesis of novel 2-mercapto benzothiazole and 1,2,3-triazole based bis-heterocycles: Their anti-inflammatory and anti-nociceptive activities

(2012) Syed Shafi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Copper-Catalyzed Azide–Alkyne Cycloaddition Reaction in Water Using Cyclodextrin as a Phase Transfer Catalyst

(2012) Jung-Ah Shin et al.   JOURNAL OF ORGANIC CHEMISTRY

Comprehensive analysis of methods used for the evaluation of compounds against Mycobacterium tuberculosis

(2012) Scott G. Franzblau et al.   TUBERCULOSIS

Novel 1,2,3-Triazole Derivatives for Use againstMycobacterium tuberculosisH37Rv (ATCC 27294) Strain

(2011) Nubia Boechat et al.   JOURNAL OF MEDICINAL CHEMISTRY

Targeting tuberculosis through a small focused library of 1,2,3-triazoles

(2011) Guillermo R. Labadie et al.   MOLECULAR DIVERSITY

Pyrazinamide Resistance and pncA Gene Mutations in Mycobacterium tuberculosis

(2008) P. Jureen et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Trifluoromethyl ethers – synthesis and properties of an unusual substituent

(2008) Frédéric R Leroux et al.   Beilstein Journal of Organic Chemistry

Understanding organofluorine chemistry. An introduction to the C–F bond

(2007) David O'Hagan   CHEMICAL SOCIETY REVIEWS