IFN Regulatory Factor 1 Mediates Macrophage Pyroptosis Induced by Oxidized Low-Density Lipoprotein in Patients with Acute Coronary Syndrome

IRF2 transcriptionally induces GSDMD expression for pyroptosis

(2019) Nobuhiko Kayagaki et al.   Science Signaling

Single-cell analysis of pyroptosis dynamics reveals conserved GSDMD-mediated subcellular events that precede plasma membrane rupture

(2018) Nathalia M. de Vasconcelos et al.   CELL DEATH AND DIFFERENTIATION

Pyroptosis and its relationship to atherosclerosis

(2018) Yuan-Jun Xu et al.   CLINICA CHIMICA ACTA

The impact of interferon-regulatory factors to macrophage differentiation and polarization into M1 and M2

(2018) Dimitry A. Chistiakov et al.   IMMUNOBIOLOGY

Role of interferon regulatory factor 1 in governing Treg depletion, Th1 polarization, inflammasome activation and antitumor efficacy of cyclophosphamide

(2017) Carla Buccione et al.   INTERNATIONAL JOURNAL OF CANCER

Role of NLRP3 Inflammasomes in Atherosclerosis

(2017) Tadayoshi Karasawa et al.   Journal of Atherosclerosis and Thrombosis

Oncostatin M receptor β deficiency attenuates atherogenesis by inhibiting JAK2/STAT3 signaling in macrophages

(2017) Xin Zhang et al.   JOURNAL OF LIPID RESEARCH

The immunology of atherosclerosis

(2017) Anton Gisterå et al.   Nature Reviews Nephrology

Effects of IRF1 and IFN-β interaction on the M1 polarization of macrophages and its antitumor function

(2016) CHANGLI XIE et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

NOD-Like Receptors in Infection, Immunity, and Diseases

(2016) Young Keun Kim et al.   YONSEI MEDICAL JOURNAL

Early Hyperlipidemia Promotes Endothelial Activation via a Caspase-1-Sirtuin 1 PathwaySignificance

(2015) Ying Yin et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

IFN Regulatory Factor-1 Modulates the Function of Dendritic Cells in Patients with Acute Coronary Syndrome

(2015) Min Guo et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling

(2015) Nobuhiko Kayagaki et al.   NATURE

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

(2015) Jianjin Shi et al.   NATURE

Mechanisms and Functions of Inflammasomes

(2014) Mohamed Lamkanfi et al.   CELL

I B Kinase   Targets Interferon Regulatory Factor 1 in Activated T Lymphocytes

(2014) M. Sgarbanti et al.   MOLECULAR AND CELLULAR BIOLOGY

Inflammasome-mediated pyroptotic and apoptotic cell death, and defense against infection

(2013) Youssef Aachoui et al.   CURRENT OPINION IN MICROBIOLOGY

Inflammasomes: sensors of metabolic stresses for vascular inflammation 

(2013) Xiao-feng Yang   Frontiers in Bioscience-Landmark

Pyroptosis: An inflammatory cell death implicates in atherosclerosis

(2013) Wei Chang et al.   MEDICAL HYPOTHESES

Oxidized Low Density Lipoprotein Induced Caspase-1 Mediated Pyroptotic Cell Death in Macrophages: Implication in Lesion Instability?

(2013) Jing Lin et al.   PLoS One

Interferon regulatory factor 1 regulation of oligodendrocyte injury and inflammatory demyelination

(2012) Eileah Loda et al.   REVIEWS IN THE NEUROSCIENCES

Cell Death, Damage-Associated Molecular Patterns, and Sterile Inflammation in Cardiovascular Disease

(2011) Yue Zheng et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Macrophages in the Pathogenesis of Atherosclerosis

(2011) Kathryn J. Moore et al.   CELL

Caspase-1-induced pyroptotic cell death

(2011) Edward A. Miao et al.   IMMUNOLOGICAL REVIEWS

IRF-1 signaling in central nervous system glial cells regulates inflammatory demyelination

(2011) Zhihua Ren et al.   JOURNAL OF NEUROIMMUNOLOGY

Overexpression of the Dominant-Negative Form of Interferon Regulatory Factor 1 in Oligodendrocytes Protects against Experimental Autoimmune Encephalomyelitis

(2011) Z. Ren et al.   JOURNAL OF NEUROSCIENCE

Non-canonical inflammasome activation targets caspase-11

(2011) Nobuhiko Kayagaki et al.   NATURE

The Inflammasomes

(2010) Kate Schroder et al.   CELL

miR-146a in PBMCs modulates Th1 function in patients with acute coronary syndrome

(2010) Min Guo et al.   IMMUNOLOGY AND CELL BIOLOGY

Inhibition of IFN Regulatory Factor-1 Down-Regulate Th1 Cell Function in Patients with Acute Coronary Syndrome

(2010) Min Guo et al.   JOURNAL OF CLINICAL IMMUNOLOGY

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

(2010) Peter Duewell et al.   NATURE

Vascular Smooth Muscle Cell Apoptosis Induces Interleukin-1–Directed Inflammation

(2009) Murray C.H. Clarke et al.   CIRCULATION RESEARCH

STAT1/IRF-1 signaling pathway mediates the injurious effect of interferon-gamma on oligodendrocyte progenitor cells

(2009) Yan Wang et al.   GLIA

Cell death in the host response to infection

(2008) K Labbé et al.   CELL DEATH AND DIFFERENTIATION

Regulation of macrophage function in inflammation and atherosclerosis: Fig. 1.

(2008) Norihito Shibata et al.   JOURNAL OF LIPID RESEARCH