4.7 Review

The Antioxidant Activity of Polysaccharides Derived from Marine Organisms: An Overview

Journal

MARINE DRUGS
Volume 17, Issue 12, Pages -

Publisher

MDPI
DOI: 10.3390/md17120674

Keywords

antioxidant activity; marine organisms; polysaccharides; chemical composition; structural characteristics; structure-activity relationship

Funding

  1. National Key Research and Development Program [2017YFE0103100]
  2. National Natural Science Foundation of China [81773628, 81741165, 41776139]

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Marine-derived antioxidant polysaccharides have aroused extensive attention because of their potential nutritional and therapeutic benefits. However, the comprehensive comparison of identified marine-derived antioxidant polysaccharides is still inaccessible, which would facilitate the discovery of more efficient antioxidants from marine organisms. Thus, this review summarizes the sources, chemical composition, structural characteristics, and antioxidant capacity of marine antioxidant polysaccharides, as well as their protective in vivo effects mediated by antioxidative stress reported in the last few years (2013-2019), and especially highlights the dominant role of marine algae as antioxidant polysaccharide source. In addition, the relationships between the chemical composition and structural characteristics of marine antioxidant polysaccharides with their antioxidant capacity were also discussed. The antioxidant activity was found to be determined by multiple factors, including molecular weight, monosaccharide composition, sulfate position and its degree.

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