Article
Dermatology
Jing Li, Fangfang Duan, Jie Kuang
Summary: This study compared the efficacy and safety of fractional picosecond laser (FPL) with non-picosecond fractional lasers (FLs) for acne scars. The results showed that there was no significant difference in clinical improvement of atrophic acne scars between the two types of lasers. However, FPL had a lower risk of post-inflammatory hyperpigmentation (PIH) and pain scores. Therefore, FPL is more suitable for acne scar patients prone to PIH or sensitive to pain.
JOURNAL OF COSMETIC DERMATOLOGY
(2023)
Article
Dermatology
Ximeng Jia, Lingyu Zheng, Lin Fang, Ling Zhang, Ying Wu, Yang Yang, Yongqiang Feng, Lvping Huang
Summary: This study evaluated the efficacy and safety of fractional 1064 nm picosecond Nd:YAG laser in treating post-acne erythema in adult Chinese patients. The results showed that FPNYL is an effective and safe treatment option based on various assessment scales.
SKIN RESEARCH AND TECHNOLOGY
(2023)
Article
Dermatology
Punyaphat Sirithanabadeekul, Ploypailin Tantrapornpong, Bheeratida Rattakul, Nalinee Sutthipisal, Wilai Thanasarnaksorn
Summary: This study found that FxPico was as effective as FxCO(2) in treating facial atrophic acne scars, with FxPico showing a better safety profile and causing fewer cases of postinflammatory hyperpigmentation.
DERMATOLOGIC SURGERY
(2021)
Article
Multidisciplinary Sciences
Aya Reda Mohamed Hawwas, Hassan Abou Khodair Mohamed, Osama Magdy Elshahat Sayedahmed, Mohamed L. Elsaie
Summary: This study aimed to compare the efficacy of topical timolol maleate 0.5% after fractional CO2 laser with fractional CO2 laser alone for treating atrophic acne scars. A split-face experiment on 30 cases showed that both treatments resulted in significant improvement, with better results observed in the laser + timolol group, but not significantly higher than the laser only group. The study concludes that both treatments can achieve comparable significant improvement, and suggests further verification through larger sample and controlled trials to confirm the benefits of timolol for acne scars.
SCIENTIFIC REPORTS
(2023)
Article
Dermatology
Hao Feng, Yuemeng Wu, Min Jiang, Xiaoqun Luo, Shuxian Yan, Zhong Lu
Summary: Combined treatment with 1064 nm Nd:YAG picosecond laser and IPL is effective, efficient, and safe for atrophic acne scars with post-inflammatory erythema.
LASERS IN SURGERY AND MEDICINE
(2021)
Article
Medicine, General & Internal
Zhonglan Pan, Yanqiu Tang, Hui Hua, Zuoqiong Hou, Bingrong Zhou
Summary: This study evaluated the efficacy and safety of a new modality combining ultra-pulse CO2 laser and fractional CO2 laser (MMP) in the treatment of acne atrophic scars. The results showed that MMP can effectively reduce the severity of atrophic scars with limited adverse reactions.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Jemin Kim, Sang Gyu Lee, Sooyeon Choi, Joohee Lee, Young In Lee, Jihee Kim, Ju Hee Lee
Summary: This study aimed to evaluate the efficacy of combining FMR and AFL in treating acne and acne scars compared to AFL alone. The results showed that the FMR+AFL treatment had superior efficacy in treating inflammatory acne and acne scars compared to AFL alone. The side effects were minimal and well-tolerated in both groups.
YONSEI MEDICAL JOURNAL
(2023)
Article
Dermatology
Shereen Osama Tawfic, Rania Abdel Hay, Hadeel Salim, Maha Fathy Elmasry
Summary: This study compared the efficacy of low-power fractional CO2 laser and TXA microinjection for post-acne hyperpigmentation, showing both treatments are effective with potential superiority of fractional CO2 laser. Dermoscopy could be a helpful tool for assessing pigmentation depth in patients on treatment.
DERMATOLOGIC THERAPY
(2021)
Article
Dermatology
Edward Ross, William J. Tidwell, Lark Guss, Adam Sutton
Summary: In this study, picosecond fractional lasers were used to treat wrinkles and mottled pigment. Results showed that the lasers achieved significant reduction in fine lines and pigmentation, with approximately 93% of patients experiencing moderate improvement in pigmentation and fine lines/wrinkles 1 month after treatment.
DERMATOLOGIC SURGERY
(2022)
Review
Dermatology
Rezvan Amiri, Maryam Khalili, Saman Mohammadi, Behzad Iranmanesh, Mahin Aflatoonian
Summary: Light and laser treatments are effective modalities in reducing acne-induced erythema, active acne lesions, and atrophic acne scars.
JOURNAL OF COSMETIC DERMATOLOGY
(2022)
Article
Medicine, General & Internal
Lei Chen, Yanjin Wang, Lili Jiang, Jing Fang, Jizhen Ren
Summary: The three treatment modes are effective in treating concave acne scars, with the combined mode group being the most effective but also having the most severe side effects; the fractional ablative mode group achieves the best balance between treatment effect and side effects.
Article
Medicine, General & Internal
Surong Liang, Shuai Shang, Wensi Zhang, Ansheng Tan, Boyang Zhou, Xueling Mei, Linfeng Li
Summary: Background: Picosecond lasers have been proven effective and safe for melasma, but there are limited randomized controlled trials (RCTs) on this topic. The objective of this study was to compare the efficacy and safety of non-fractional picosecond Nd:YAG laser, non-fractional picosecond alexandrite laser, and 2% hydroquinone cream in the treatment of melasma.
FRONTIERS IN MEDICINE
(2023)
Article
Dermatology
Rongxin Ren, Hongyi Zhao
Summary: Post-inflammatory hyperpigmentation is a common sequela of skin inflammation. Treatments for PIH include topical agents and laser therapy. In this case, a 755-nm alexandrite picosecond laser was used to successfully treat nasal PIH in a 36-year-old female patient.
JOURNAL OF COSMETIC DERMATOLOGY
(2022)
Article
Dermatology
Kristoffer Hendel, Katrine Karmisholt, Lene Hedelund, Merete Haedersdal
Summary: This study compared the efficacy of ablative fractional CO2 laser (AFL) and microneedle radiofrequency (MNRF) treatments for acne scars. The results showed that both treatments were equally effective at improving the texture of the skin. AFL caused more intense local skin reactions, while MNRF was more painful. Overall, patients were generally satisfied with the outcome of both treatments.
LASERS IN SURGERY AND MEDICINE
(2023)
Article
Dermatology
Xiaoxi Cheng, Qing Yang, Yingjun Su, Yanqiu Wu, Xianjie Ma
Summary: The study compared the effectiveness and safety of 1565-nm NAFL and 10,600-nm AFL in treating mild-to-moderate facial atrophic acne scars, with results showing that 1565-nm NAFL was more effective in reducing erythema, crusting durations, and degree of pain compared to 10,600-nm AFL.
DERMATOLOGIC SURGERY
(2021)
Article
Dermatology
Yin Yang, Yiping Ge, Lifang Guo, Qiuju Wu, Lin Peng, Erjia Zhang, Junxiang Xie, Yong Li, Tong Lin
Summary: This study utilized deep learning for diagnosing common, benign hyperpigmentation by establishing a diagnostic model based on convolutional neural networks. Through comparative analysis, it was found that the converged network had the best performance compared to individual networks.
SKIN RESEARCH AND TECHNOLOGY
(2021)
Article
Oncology
Jia-An Zhang, Xu-Yue Zhou, Dan Huang, Chao Luan, Heng Gu, Mei Ju, Kun Chen
Summary: This study aimed to explore the immune infiltration characteristics of melanoma and identified immune-related core genes and relevant immune cell subtypes, which may provide new targeted approaches for the treatment of melanoma.
FRONTIERS IN ONCOLOGY
(2021)
Letter
Dermatology
Rong Zeng, Qiujv Wu, Lifang Guo, Tong Lin
INDIAN JOURNAL OF DERMATOLOGY VENEREOLOGY & LEPROLOGY
(2021)
Article
Dermatology
Mengli Zhang, Yang Guan, Yuqing Huang, Erjia Zhang, Tong Lin, Qiuju Wu
Summary: The study found that PSL treatment induced intraepidermal vacuoles, pigment accumulation, and inflammatory cell infiltration in in vivo skin specimens. High-fluence, multi-pass PSL treatment resulted in more intraepidermal vacuoles, along with dermal hemorrhage and inflammatory cell infiltration. Dermal and epidermal vacuoles were observed in ex vivo skin specimens.
LASERS IN SURGERY AND MEDICINE
(2021)
Article
Oncology
Shiqin Tao, Zixi Wang, Cheng Quan, Yiping Ge, Qihong Qian
Summary: ALA-PDT shows therapeutic effects in controlling severe acne by killing C. acnes, increasing P. fluorescens and microbiome diversity, while inhibiting the relative abundance of functional genes involved in pilosebaceous units of severe acne.
PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY
(2021)
Article
Dermatology
Mengli Zhang, Yuqing Huang, Qiuju Wu, Tong Lin, Xiangdong Gong, Hao Chen, Yan Wang
Summary: This study compared the efficacy and safety of 1064-nm and 532/1064-nm picosecond Nd:YAG lasers in treating facial photoaging. Both lasers significantly improved global photoaging scores, with no significant differences in outcomes between the two treatments. Histological changes were similar between the two groups, showing improvements in collagen and elastin networks.
LASERS IN SURGERY AND MEDICINE
(2021)
Review
Oncology
Lei Shi, Hongwei Wang, Kun Chen, Jia Yan, Bo Yu, Shengchun Wang, Rui Yin, Xiang Nong, Xianbiao Zou, Zhou Chen, Chengxin Li, Liuqing Chen, Chunlei Zhang, Furen Zhang, Heyi Zheng, Min Zheng, Ping Tu, Jinhua Xu, Juan Tao, Xiaojing Kang, Kang Zeng, Yan Lu, Nan Yu, Xia Lei, Meng Pan, Qiang Ju, Heng Gu, Xiuli Wang
Summary: The expert group revised and updated the first edition of the expert consensus statement on Clinical application of 5-aminolevulinic acid-based photodynamic therapy, providing Chinese dermatologists with updated treatment references.
PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY
(2021)
Article
Dermatology
Yin Yang, Lifang Guo, Qiuju Wu, Mengli Zhang, Rong Zeng, Hui Ding, Huiying Zheng, Junxiang Xie, Yong Li, Yiping Ge, Min Li, Tong Lin
Summary: The study aimed to achieve standardized diagnosis and treatment of acne vulgaris using a deep learning model based on current Chinese guidelines. Results showed high consistency between the evaluation model and attending dermatologists, with an average F1 value of 0.8 and weighted kappa coefficient of 0.791.
DERMATOLOGY AND THERAPY
(2021)
Article
Oncology
Jiaan Zhang, Xuyue Zhou, Chenpu Zhu, Yu Hu, Rong Li, Shuang Jin, Dan Huang, Mei Ju, Kun Chen, Chao Luan
Summary: Cutaneous basal cell carcinoma (BCC) is a common subtype of skin cancer with low invasiveness. This study identified differentially expressed lncRNAs and mRNAs in BCC and constructed a co-expression network, providing insights into potential biological markers and pathways involved in the progression of BCC.
MOLECULAR MEDICINE REPORTS
(2021)
Article
Dermatology
Shuang Jin, Linxi Liu, Rong Li, Xuyue Zhou, Ziwei Wang, Chao Luan, Kun Chen, Dan Huang
Summary: Giant condyloma acuminatum, also known as Buschke-Lowenstein tumor, is a rare tumor associated with low-risk HPV types 6 or 11 in the anorectal area and external genitalia. It has a high rate of recurrence and malignant transformation. Despite being difficult to treat, there are rare cases of self-healing reported.
DERMATOLOGIC THERAPY
(2022)
Article
Dermatology
Hedan Yang, Lifang Guo, Gaorong Jia, Xiangdong Gong, Qiuju Wu, Rong Zeng, Mengli Zhang, Hui Ding, Fumin Fang, Huiying Zheng, Xing Liu, Yiping Ge, Yin Yang, Tong Lin
Summary: The study evaluated the efficacy and safety of a 1064 nm picosecond Nd:YAG laser for the treatment of nevus of Ota, showing that this laser is an effective and safe approach for treating the condition.
DERMATOLOGIC THERAPY
(2021)
Article
Dermatology
Chao Luan, Yu Hu, Mei Ju, Dan Huang, Rong-Lin Zhang, Xiao-Hua Zhang, Pan-Pan Tian, Yan Zhu, Chen Zhuang, Jia-An Zhang, Kun Chen
Summary: The study investigated the efficacy and safety of 308-nm LED for vitiligo treatment, finding varying treatment responses across different anatomical regions, with facial lesions showing the best response to treatment.
PHOTODERMATOLOGY PHOTOIMMUNOLOGY & PHOTOMEDICINE
(2022)
Article
Oncology
Yin Yang, Shiqin Tao, Rong Zeng, Huiying Zheng, Yiping Ge
Summary: ALA-PDT is effective in treating acne by inhibiting C. acnes and modulating the composition and potential function of skin microbiome.
PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY
(2021)
Article
Engineering, Biomedical
Fumin Fang, Hedan Yang, Xing Liu, Hui Ding, Yin Yang, Yiping Ge, Tong Lin
Summary: This retrospective study investigated the efficacy of ablative fractional carbon dioxide (CO2) laser treatment for atrophic acne scars in Asians. The study found that three treatment sessions and pigmentation lasting less than three months resulted in better outcomes, regardless of energy, gender, age, Fitzpatrick skin type, follow-up duration, and disease course.
LASERS IN MEDICAL SCIENCE
(2022)
Letter
Allergy
Dan Huang, Shuang Jin, Wei Zhang, Xuyue Zhou, Rong Li, Kun Chen, Mei Ju
POSTEPY DERMATOLOGII I ALERGOLOGII
(2021)