Defining body-weight reduction as a humane endpoint: a critical appraisal

Dandelion root extract protects NCM460 colonic cells and relieves experimental mouse colitis

(2018) Aiguo Ding et al.   Journal of Natural Medicines

Intracranial rat glioma model for tumor resection and local treatment

(2018) Zhiqun Wu et al.   JOURNAL OF NEUROSCIENCE METHODS

Running in the wheel: Defining individual severity levels in mice

(2018) Christine Häger et al.   PLOS BIOLOGY

Toward a Wiring Diagram Understanding of Appetite Control

(2017) Mark L. Andermann et al.   NEURON

Caloric restriction reduces the systemic progression of mouse AApoAII amyloidosis

(2017) Lin Li et al.   PLoS One

Long-term caloric restriction in ApoE-deficient mice results in neuroprotection via Fgf21-induced AMPK/mTOR pathway

(2016) Claire Rühlmann et al.   Aging-US

Pharmacotherapy for Dravet Syndrome

(2016) Adam Wallace et al.   PEDIATRIC DRUGS

Implementation of a manual for working with wobbler mice and criteria for discontinuation of the experiment

(2015) Bastian Ott et al.   ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER

Celastrol Protects against Obesity and Metabolic Dysfunction through Activation of a HSF1-PGC1α Transcriptional Axis

(2015) Xinran Ma et al.   Cell Metabolism

Analysis in conditional cannabinoid 1 receptor-knockout mice reveals neuronal subpopulation-specific effects on epileptogenesis in the kindling paradigm

(2015) E.L. von Rüden et al.   NEUROBIOLOGY OF DISEASE

An Efficient Chronic Unpredictable Stress Protocol to Induce Stress-Related Responses in C57BL/6 Mice

(2015) Susana Monteiro et al.   Frontiers in Psychiatry

The Conditioned Place Preference Test for Assessing Welfare Consequences and Potential Refinements in a Mouse Bladder Cancer Model

(2014) John V. Roughan et al.   PLoS One

Endpoint Matrix: a conceptual tool to promote consideration of the multiple dimensions of humane endpoints

(2014) Vanessa Ashall   ALTEX-Alternatives to Animal Experimentation

Lifelong Caloric Restriction Reprograms Hepatic Fat Metabolism in Mice

(2013) A. Kuhla et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Lifelong Caloric Restriction Increases Working Memory in Mice

(2013) Angela Kuhla et al.   PLoS One

How “Humane” Is Your Endpoint?—Refining the Science-Driven Approach for Termination of Animal Studies of Chronic Infection

(2012) Nuno H. Franco et al.   PLoS Pathogens

The law through the eye of a needle

(2011) Laura Ricceri et al.   EMBO REPORTS

Caloric restriction and brain function

(2008) Sophie Gillette-Guyonnet et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE