Suppression of Progranulin Expression Leads to Formation of Intranuclear TDP-43 Inclusions In Vitro: A Cell Model of Frontotemporal Lobar Degeneration

Revisiting the utility of TDP-43 immunoreactive (TDP-43-ir) pathology to classify FTLD-TDP subtypes

(2019) Yasushi Nishihira et al.   ACTA NEUROPATHOLOGICA

Frontotemporal Lobar Degeneration (FTLD): Review and Update for Clinical Neurologists

(2018) Isabel Hernandez et al.   Current Alzheimer Research

Biological function analysis of monoclonal antibodies against human granulins in vitro using U251 cells as a model

(2017) Yanqing Li et al.   PROTEIN EXPRESSION AND PURIFICATION

Progranulin in neurodegenerative disease

(2014) Terri L. Petkau et al.   TRENDS IN NEUROSCIENCES

Strikingly Different Clinicopathological Phenotypes Determined by Progranulin-Mutation Dosage

(2012) Katherine R. Smith et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury

(2012) Lauren Herl Martens et al.   JOURNAL OF CLINICAL INVESTIGATION

A harmonized classification system for FTLD-TDP pathology

(2011) Ian R. A. Mackenzie et al.   ACTA NEUROPATHOLOGICA

Recent Insights into the Involvement of Progranulin in Frontotemporal Dementia

(2011) Li Sun et al.   Current Neuropharmacology

Domain-Specific Monoclonal Antibodies Produced Against Human PGRN

(2011) Lihong Chai et al.   HYBRIDOMA

Progranulin Deficiency Decreases Gross Neural Connectivity But Enhances Transmission at Individual Synapses

(2011) L. Tapia et al.   JOURNAL OF NEUROSCIENCE

Exaggerated inflammation, impaired host defense, and neuropathology in progranulin-deficient mice

(2009) Fangfang Yin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Progranulin functions as a neurotrophic factor to regulate neurite outgrowth and enhance neuronal survival

(2008) Philip Van Damme et al.   JOURNAL OF CELL BIOLOGY