Synergistic effect of phosphorothioate, 5′-vinylphosphonate and GalNAc modifications for enhancing activity of synthetic siRNA

Published 2016 View Full Article

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Title
Synergistic effect of phosphorothioate, 5′-vinylphosphonate and GalNAc modifications for enhancing activity of synthetic siRNA
Authors
Keywords
3′-GalNAc cluster, 5′-Vinylphosphonate siRNA, Fully modified siRNA, Alternating F/OMe siRNA, siRNA phosphorothioates
Journal
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 26, Issue 12, Pages 2817-2820
Publisher
Elsevier BV
Online
2016-04-30
DOI
10.1016/j.bmcl.2016.04.063

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