Selectivity switch between FAK and Pyk2: Macrocyclization of FAK inhibitors improves Pyk2 potency

Published 2016 View Full Article

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Title
Selectivity switch between FAK and Pyk2: Macrocyclization of FAK inhibitors improves Pyk2 potency
Authors
Keywords
Pyk2, FAK, Macrocycle, Atropisomer, Glioblastoma
Journal
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 26, Issue 24, Pages 5926-5930
Publisher
Elsevier BV
Online
2016-11-02
DOI
10.1016/j.bmcl.2016.10.092

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