Development of thieno- and benzopyrimidinone inhibitors of the Hedgehog signaling pathway reveals PDE4-dependent and PDE4-independent mechanisms of action

Title
Development of thieno- and benzopyrimidinone inhibitors of the Hedgehog signaling pathway reveals PDE4-dependent and PDE4-independent mechanisms of action
Authors
Keywords
Hedgehog signaling pathway, Eggmanone, Suppressor of Fused, Phenotypic screening, Probe development
Journal
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 26, Issue 8, Pages 1947-1953
Publisher
Elsevier BV
Online
2016-03-08
DOI
10.1016/j.bmcl.2016.03.013

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