Design, synthesis and in vitro evaluation of benzothiazole-based ureas as potential ABAD/17β-HSD10 modulators for Alzheimer’s disease treatment

Published 2016 View Full Article

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Title
Design, synthesis and in vitro evaluation of benzothiazole-based ureas as potential ABAD/17β-HSD10 modulators for Alzheimer’s disease treatment
Authors
Keywords
Alzheimer’s disease (AD), Amyloid-beta peptide (Aβ), Mitochondria, Amyloid binding alcohol dehydrogenase (ABAD), 17β-Hydroxysteroid dehydrogenase type 10 (17β-HSD10), Benzothiazole, Riluzole
Journal
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 26, Issue 15, Pages 3675-3678
Publisher
Elsevier BV
Online
2016-05-31
DOI
10.1016/j.bmcl.2016.05.087

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