Discovery of selective inhibitors of tyrosyl-DNA phosphodiesterase 2 by targeting the enzyme DNA-binding cleft

Title
Discovery of selective inhibitors of tyrosyl-DNA phosphodiesterase 2 by targeting the enzyme DNA-binding cleft
Authors
Keywords
Tyrosyl-DNA phosphodiesterase 2, TDP2, Inhibitor, Virtual screening, Rational drug design
Journal
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 26, Issue 14, Pages 3232-3236
Publisher
Elsevier BV
Online
2016-05-25
DOI
10.1016/j.bmcl.2016.05.065

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