A homozygous SFTPA1 mutation drives necroptosis of type II alveolar epithelial cells in patients with idiopathic pulmonary fibrosis

Necroptosis in development and diseases

(2018) Bing Shan et al.   GENES & DEVELOPMENT

Diagnosis of Idiopathic Pulmonary Fibrosis. An Official ATS/ERS/JRS/ALAT Clinical Practice Guideline

(2018) Ganesh Raghu et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Necroptosis and RIPK1-mediated neuroinflammation in CNS diseases

(2018) Junying Yuan et al.   NATURE REVIEWS NEUROSCIENCE

Patients With Fibrotic Interstitial Lung Disease Hospitalized for Acute Respiratory Worsening

(2016) Teng Moua et al.   CHEST

GermlineSFTPA1mutation in familial idiopathic interstitial pneumonia and lung cancer

(2016) Nadia Nathan et al.   HUMAN MOLECULAR GENETICS

Necroptosis and its role in inflammation

(2015) Manolis Pasparakis et al.   NATURE

The diverse role of RIP kinases in necroptosis and inflammation

(2015) John Silke et al.   NATURE IMMUNOLOGY

Genetics and Early Detection in Idiopathic Pulmonary Fibrosis

(2014) Rachel K. Putman et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

New Therapeutic Targets in Idiopathic Pulmonary Fibrosis. Aiming to Rein in Runaway Wound-Healing Responses

(2014) Neil Ahluwalia et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

RIPK1 Regulates RIPK3-MLKL-Driven Systemic Inflammation and Emergency Hematopoiesis

(2014) James A. Rickard et al.   CELL

An inherited mutation inNLRC4causes autoinflammation in human and mice

(2014) Akiko Kitamura et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Regulated necrosis: the expanding network of non-apoptotic cell death pathways

(2014) Tom Vanden Berghe et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Efficacy and Safety of Nintedanib in Idiopathic Pulmonary Fibrosis

(2014) Luca Richeldi et al.   NEW ENGLAND JOURNAL OF MEDICINE

ER stress-induced cell death mechanisms

(2013) Renata Sano et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis

(2013) Jianfeng Wu et al.   CELL RESEARCH

RIP3: a molecular switch for necrosis and inflammation

(2013) K. Moriwaki et al.   GENES & DEVELOPMENT

Telomeres and age-related disease: how telomere biology informs clinical paradigms

(2013) Mary Armanios   JOURNAL OF CLINICAL INVESTIGATION

Emerging evidence for endoplasmic reticulum stress in the pathogenesis of idiopathic pulmonary fibrosis

(2012) Harikrishna Tanjore et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Molecular Mechanisms in Progressive Idiopathic Pulmonary Fibrosis

(2012) Mark P. Steele et al.   Annual Review of Medicine

Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase

(2012) Liming Sun et al.   CELL

The RIP1/RIP3 Necrosome Forms a Functional Amyloid Signaling Complex Required for Programmed Necrosis

(2012) Jixi Li et al.   CELL

Pulmonary fibrosis: patterns and perpetrators

(2012) Paul W. Noble et al.   JOURNAL OF CLINICAL INVESTIGATION

Idiopathic Pulmonary Fibrosis: Increased Survival with “Gastroesophageal Reflux Therapy”

(2011) Ganesh Raghu   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Novel therapeutic approaches for pulmonary fibrosis

(2011) Arnab Datta et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Adaptor Protein FADD Protects Epidermal Keratinocytes from Necroptosis In Vivo and Prevents Skin Inflammation

(2011) Marion C. Bonnet et al.   IMMUNITY

A mutation in the immunoproteasome subunit PSMB8 causes autoinflammation and lipodystrophy in humans

(2011) Akiko Kitamura et al.   JOURNAL OF CLINICAL INVESTIGATION

FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation

(2011) Patrick-Simon Welz et al.   NATURE

Efficacy of a Tyrosine Kinase Inhibitor in Idiopathic Pulmonary Fibrosis

(2011) Luca Richeldi et al.   NEW ENGLAND JOURNAL OF MEDICINE

A CommonMUC5BPromoter Polymorphism and Pulmonary Fibrosis

(2011) Max A. Seibold et al.   NEW ENGLAND JOURNAL OF MEDICINE

Toll-like receptors activate programmed necrosis in macrophages through a receptor-interacting kinase-3-mediated pathway

(2011) S. He et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pulmonary Hypertension and Idiopathic Pulmonary Fibrosis

(2010) Laszlo Farkas et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Surfactant Protein A2 Mutations Associated with Pulmonary Fibrosis Lead to Protein Instability and Endoplasmic Reticulum Stress

(2010) Meenakshi Maitra et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Surface expression of CD74 by type II alveolar epithelial cells: a potential mechanism for macrophage migration inhibitory factor-induced epithelial repair

(2009) Leigh M. Marsh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

HomozygosityMapper--an interactive approach to homozygosity mapping

(2009) D. Seelow et al.   NUCLEIC ACIDS RESEARCH

Intranasal administration of a live non-pathogenic avian H5N1 influenza virus from a virus library confers protective immunity against H5N1 highly pathogenic avian influenza virus infection in mice: Comparison of formulations and administration routes of vaccines

(2009) Yoshitaka Kashima et al.   VACCINE

Genetic Defects in Surfactant Protein A2 Are Associated with Pulmonary Fibrosis and Lung Cancer

(2008) Yongyu Wang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Epithelial Endoplasmic Reticulum Stress and Apoptosis in Sporadic Idiopathic Pulmonary Fibrosis

(2008) Martina Korfei et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Necroptosis: A Specialized Pathway of Programmed Necrosis

(2008) Lorenzo Galluzzi et al.   CELL