Synthesis and biological evaluation of azole-diphenylpyrimidine derivatives (AzDPPYs) as potent T790M mutant form of epidermal growth factor receptor inhibitors

Title
Synthesis and biological evaluation of azole-diphenylpyrimidine derivatives (AzDPPYs) as potent T790M mutant form of epidermal growth factor receptor inhibitors
Authors
Keywords
NSCLC, EGFR T790M, Inhibitors, Synthesis, Azole-diphenylpyrimidine
Journal
BIOORGANIC & MEDICINAL CHEMISTRY
Volume 24, Issue 21, Pages 5505-5512
Publisher
Elsevier BV
Online
2016-09-09
DOI
10.1016/j.bmc.2016.09.001

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