Serial incorporation of a monovalent GalNAc phosphoramidite unit into hepatocyte-targeting antisense oligonucleotides

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Title
Serial incorporation of a monovalent GalNAc phosphoramidite unit into hepatocyte-targeting antisense oligonucleotides
Authors
Keywords
Antisense oligonucleotides, GalNAc, Asialoglycoprotein receptors, Bio-labile linker, Bridged nucleic acid, Locked nucleic acid, Apolipoproteins, Hypercholesterolemia
Journal
BIOORGANIC & MEDICINAL CHEMISTRY
Volume 24, Issue 1, Pages 26-32
Publisher
Elsevier BV
Online
2015-11-28
DOI
10.1016/j.bmc.2015.11.036

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