The human tyrosine kinase Kit and its gatekeeper mutant T670I, show different kinetic properties: Implications for drug design

Published 2016 View Full Article

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Title
The human tyrosine kinase Kit and its gatekeeper mutant T670I, show different kinetic properties: Implications for drug design
Authors
Keywords
Kit, Enzyme kinetics, Tyrosine kinases, Drug resistance
Journal
BIOORGANIC & MEDICINAL CHEMISTRY
Volume 24, Issue 19, Pages 4555-4562
Publisher
Elsevier BV
Online
2016-08-04
DOI
10.1016/j.bmc.2016.07.059

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