Design, synthesis, and evaluation of novel porcupine inhibitors featuring a fused 3-ring system based on the ‘reversed’ amide scaffold

Published 2016 View Full Article

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Title
Design, synthesis, and evaluation of novel porcupine inhibitors featuring a fused 3-ring system based on the ‘reversed’ amide scaffold
Authors
Keywords
Wnt signaling pathway, Porcupine, Antagonist, Cancer therapy, Scaffold hybridization
Journal
BIOORGANIC & MEDICINAL CHEMISTRY
Volume 24, Issue 22, Pages 5861-5872
Publisher
Elsevier BV
Online
2016-09-18
DOI
10.1016/j.bmc.2016.09.041

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