Article
Medicine, General & Internal
Enric Sanchez, Esther Sapina-Beltran, Ricard Gavalda, Ferran Barbe, Gerard Torres, Ariadna Sauret, Mireia Dalmases, Carolina Lopez-Cano, Liliana Gutierrez-Carrasquilla, Marcelino Bermudez-Lopez, Elvira Fernandez, Francisco Purroy, Eva Castro-Boque, Cristina Farras-Salles, Reinald Pamplona, Didac Mauricio, Cristina Hernandez, Rafael Simo, Albert Lecube, ILERVAS Project Collaborators
Summary: The study found that individuals in the prediabetes stage exhibited higher abnormal sleep breathing parameters compared to those with normal glucose metabolism, with a significant increase in apnea events and hypoxemia.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Tomas Konecny, Michael Khoo, Naima Covassin, Paul Edelhofer, Jan Bukartyk, Jae Yoon Park, Shreyas Venkataraman, Shahid Karim, Anwar Chahal, Tomas Kara, Marek Orban, Ondrej Ludka, Josef Kautzner, Steve R. Ommen, Virend K. Somers
Summary: This study found a positive correlation between SDB and mean HR in HCM patients, especially during nighttime. It suggests that treating SDB may serve as a complementary approach to alleviate symptoms in HCM patients.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2021)
Article
Obstetrics & Gynecology
Kim Phan, Sushmita Pamidi, Yessica-Haydee Gomez, Jessica Gorgui, Amira El-Messidi, Robert Gagnon, R. John Kimoff, Haim A. Abenhaim, Stella S. Daskalopoulou
Summary: Sleep-disordered breathing may lead to increased arterial stiffness and higher risk of preeclampsia during pregnancy, with hypersomnolence potentially exacerbating this effect.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2022)
Article
Pediatrics
Rosemary S. C. Horne, Ashwini Sakthiakumaran, Ahmad Bassam, Julie Thacker, Lisa M. Walter, Margot J. Davey, Gillian M. Nixon
Summary: Children with Down syndrome experiencing sleep disordered breathing exhibit reduced parasympathetic activity and increased exposure to hypoxia, which may lead to adverse cardiovascular outcomes compared to typically developing children. Early screening and treatment for sleep disordered breathing in children with Down syndrome is recommended.
PEDIATRIC RESEARCH
(2021)
Article
Pediatrics
Eszter Csabi, Veronika Gaal, Emese Hallgato, Rebeka Anna Schulcz, Gabor Katona, Palma Benedek
Summary: This study aimed to assess the behavioral consequences of sleep disturbances in children with sleep-disordered breathing. The results showed that children with sleep-disordered breathing exhibited higher levels of inattentiveness, hyperactive behavior, and internalizing and externalizing problems. The study suggests that even mild sleep-disordered breathing, such as snoring and mild obstructive sleep apnea, may increase the risk of behavioral and emotional dysfunctions in children.
ITALIAN JOURNAL OF PEDIATRICS
(2022)
Review
Clinical Neurology
Claudio Liguori, Michelangelo Maestri, Matteo Spanetta, Fabio Placidi, Enrica Bonanni, Nicola B. Mercuri, Biancamaria Guarnieri
Summary: Sleep-disordered breathing, particularly obstructive sleep apnea (OSA), is common in the elderly population and has been linked to an increased risk of cognitive decline and dementia, including Alzheimer's disease (AD). Studies have focused on investigating AD biomarkers in OSA patients using various methods, including cognitive tests, biofluid analysis, neuroimaging, and nuclear medicine imaging. Additionally, the effects of continuous positive airway pressure (CPAP) treatment on cognitive function and AD biomarkers in OSA patients have been explored, with a call for future studies to better understand the relationship between OSA and AD risk.
SLEEP MEDICINE REVIEWS
(2021)
Review
Critical Care Medicine
Salam Zeineddine, James A. Rowley, Susmita Chowdhuri
Summary: Sleep-disordered breathing (SDB) has significant cardiovascular and neurological effects, with supplemental oxygen therapy showing mixed results in improving oxygen saturation and apnea severity compared to positive airway pressure therapy. Further research is needed to clarify the optimal dose and duration of nocturnal supplemental oxygen (NSO) and its combination with PAP in improving cardiovascular, sleep, and cognitive outcomes in SDB patients.
Article
Chemistry, Multidisciplinary
Christian Agudelo, Alberto R. Ramos, Xiaoyan Sun, Sonya Kaur, Dylan F. Del Papa, Josefina M. Kather, Douglas M. Wallace
Summary: This study aims to identify modifiable risk factors of cognitive disease and finds that comorbid insomnia with sleep-disordered breathing (SDB) may be a modifiable risk factor for mild cognitive impairment (MCI). The results show that high risk of SDB with comorbid insomnia is associated with higher odds of MCI.
APPLIED SCIENCES-BASEL
(2022)
Article
Critical Care Medicine
Raphieal Newbold, Andrea Benedetti, R. John Kimoff, Sara Meltzer, Natasha Garfield, Kaberi Dasgupta, Robert Gagnon, Lorraine Lavigne, Allen Olha, Evelyne Rey, Sushmita Pamidi
Summary: Women with hyperglycemia during pregnancy are at high risk for adverse perinatal outcomes. Maternal sleep-disordered breathing (SDB) severity is associated with higher nocturnal and morning glucose levels in women with GDM.
Article
Clinical Neurology
Laura Perez-Carbonell, Amaia Munoz-Lopetegi, Raquel Sanchez-Valle, Ellen Gelpi, Ramon Farre, Carles Gaig, Alex Iranzo, Joan Santamaria
Summary: The study revealed that FI patients exhibit frequent breathing alterations, including various breathing disturbances, distorted NREM sleep, and severely impaired REM sleep. Brainstem impairment plays a crucial role in FI.
Article
Clinical Neurology
Brandon G. Rocque, Mary Halsey Maddox, Betsy D. Hopson, Isaac C. Shamblin, Inmaculada Aban, Anastasia A. Arynchyna, Jeffrey P. Blount
Summary: This study found a high prevalence of sleep disordered breathing in children with myelomeningocele through screening polysomnography, suggesting the need for routine screening in this population. Children with higher neurological lesion levels were more likely to have sleep disordered breathing.
Review
Pediatrics
Pablo E. Brockmann, David Gozal
Summary: Sleep-disordered breathing (SDB) is a common disease in children characterized by snoring and upper airway narrowing, leading to gas exchange abnormalities and sleep fragmentation. SDB is associated with problematic behaviors and adverse neurocognitive consequences in children, but the causality and determinants of susceptibility are still not fully understood. Some children with SDB develop these consequences, but the severity of SDB based on standard diagnostic indices often fails to determine neurocognitive risk. Therefore, the search for markers and clinically useful tools to detect children with SDB who are at greater risk of developing cognitive and behavioral deficits has been ongoing.
Article
Health Care Sciences & Services
Saleh H. Alwadei, Suliman Alsaeed, Ahmed Ibrahim Masoud, Farhan Alwadei, Khalid Gufran, Abdurahman Alwadei
Summary: This study used the Arabic version of the pediatric sleep questionnaire to identify the incidence and risk factors of sleep-disordered breathing (SDB). 13% of the children were found to be at a high risk of SDB, and factors such as habitual snoring, witnessed apnea, mouth breathing, being overweight, and bedwetting were strongly associated with the development of SDB.
Article
Pediatrics
Marisha Shetty, Margot J. Davey, Gillian M. Nixon, Lisa M. Walter, Rosemary S. C. Horne
Summary: Children with Down syndrome have lower sleep spindle activity compared to typically developing children, which is negatively correlated with daytime functioning and quality of life.
PEDIATRIC RESEARCH
(2023)
Article
Clinical Neurology
Francisco Campos-Rodriguez, Juan Santos-Morano, Bernabe Jurado-Gamez, Ignacio Osman-Garcia, Francisco Rivera-Munoz, Joseba Salguero, Pedro M. Manas-Escorza, Carmen Almeida-Gonzalez
Summary: This study investigates the relationship between the severity of sleep-disordered breathing (SDB) and the aggressiveness of prostate cancer (PC). The results suggest that despite the high prevalence of SDB in PC patients, there is no clear association between the severity of SDB and PC aggressiveness.