Hedgehog signaling promotes tumor-associated macrophage polarization to suppress intratumoral CD8+ T cell recruitment
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Hedgehog signaling promotes tumor-associated macrophage polarization to suppress intratumoral CD8+ T cell recruitment
Authors
Keywords
-
Journal
JOURNAL OF CLINICAL INVESTIGATION
Volume 129, Issue 12, Pages 5151-5162
Publisher
American Society for Clinical Investigation
Online
2019-10-22
DOI
10.1172/jci128644
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Neutrophil plasticity in the tumor microenvironment
- (2019) Morgan Giese et al. BLOOD
- Host expression of PD-L1 determines efficacy of PD-L1 pathway blockade–mediated tumor regression
- (2018) Heng Lin et al. JOURNAL OF CLINICAL INVESTIGATION
- Absence of myeloid Klf4 reduces prostate cancer growth with pro-atherosclerotic activation of tumor myeloid cells and infiltration of CD8 T cells
- (2018) David J. Barakat et al. PLoS One
- Randomized comparison of low dose cytarabine with or without glasdegib in patients with newly diagnosed acute myeloid leukemia or high-risk myelodysplastic syndrome
- (2018) Jorge E. Cortes et al. LEUKEMIA
- Inhibition of Hedgehog signaling reprograms the dysfunctional immune microenvironment in breast cancer
- (2018) Ann Hanna et al. OncoImmunology
- Interferon-inducible CXC-chemokines are crucial immune modulators and survival predictors in colorectal cancer
- (2017) Larissa Kistner et al. Oncotarget
- PI3Kγ is a molecular switch that controls immune suppression
- (2016) Megan M. Kaneda et al. NATURE
- Targeting tumor-associated macrophages to combat pancreatic cancer
- (2016) Ran Cui et al. Oncotarget
- Myeloid cells in hepatocellular carcinoma
- (2015) Shanshan Wan et al. HEPATOLOGY
- Epigenetic silencing of TH1-type chemokines shapes tumour immunity and immunotherapy
- (2015) Dongjun Peng et al. NATURE
- Non-redundant requirement for CXCR3 signalling during tumoricidal T-cell trafficking across tumour vascular checkpoints
- (2015) M. E. Mikucki et al. Nature Communications
- Prognostic Implication of M2 Macrophages Are Determined by the Proportional Balance of Tumor Associated Macrophages and Tumor Infiltrating Lymphocytes in Microsatellite-Unstable Gastric Carcinoma
- (2015) Kyung-Ju Kim et al. PLoS One
- Macrophage IL-10 Blocks CD8+ T Cell-Dependent Responses to Chemotherapy by Suppressing IL-12 Expression in Intratumoral Dendritic Cells
- (2014) Brian Ruffell et al. CANCER CELL
- Tumor-Associated Macrophages: From Mechanisms to Therapy
- (2014) Roy Noy et al. IMMUNITY
- Transcriptome-Based Network Analysis Reveals a Spectrum Model of Human Macrophage Activation
- (2014) Jia Xue et al. IMMUNITY
- Functional polarization of tumour-associated macrophages by tumour-derived lactic acid
- (2014) Oscar R. Colegio et al. NATURE
- The cellular and molecular origin of tumor-associated macrophages
- (2014) R. A. Franklin et al. SCIENCE
- A high M1/M2 ratio of tumor-associated macrophages is associated with extended survival in ovarian cancer patients
- (2014) Meiying Zhang et al. Journal of Ovarian Research
- TGF- : Guardian of T Cell Function
- (2013) S. A. Oh et al. JOURNAL OF IMMUNOLOGY
- Estimation of rat mammary tumor volume using caliper and ultrasonography measurements
- (2013) Ana Faustino-Rocha et al. LAB ANIMAL
- Multiplex Genome Engineering Using CRISPR/Cas Systems
- (2013) L. Cong et al. SCIENCE
- Macrophage plasticity and polarization: in vivo veritas
- (2012) Antonio Sica et al. JOURNAL OF CLINICAL INVESTIGATION
- The Distribution of Macrophages with a M1 or M2 Phenotype in Relation to Prognosis and the Molecular Characteristics of Colorectal Cancer
- (2012) Sofia Edin et al. PLoS One
- Hedgehog Overexpression Is Associated with Stromal Interactions and Predicts for Poor Outcome in Breast Cancer
- (2011) S. A. O'Toole et al. CANCER RESEARCH
- CXCR3 ligands: redundant, collaborative and antagonistic functions
- (2011) Joanna R Groom et al. IMMUNOLOGY AND CELL BIOLOGY
- Krüppel-like factor 4 regulates macrophage polarization
- (2011) Xudong Liao et al. JOURNAL OF CLINICAL INVESTIGATION
- Identification and manipulation of tumor associated macrophages in human cancers
- (2011) Moniek Heusinkveld et al. Journal of Translational Medicine
- Macrophage Diversity Enhances Tumor Progression and Metastasis
- (2010) Bin-Zhi Qian et al. CELL
- Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm
- (2010) Subhra K Biswas et al. NATURE IMMUNOLOGY
- Review: Targeting the Hedgehog pathway in cancer
- (2010) Sachin Gupta et al. Therapeutic Advances in Medical Oncology
- Paracrine Hedgehog Signaling in Cancer
- (2009) J.-W. Theunissen et al. CANCER RESEARCH
- Chemokine Expression in Melanoma Metastases Associated with CD8+ T-Cell Recruitment
- (2009) H. Harlin et al. CANCER RESEARCH
- Small-molecule modulators of the Sonic Hedgehog signaling pathway
- (2009) Benjamin Z. Stanton et al. Molecular BioSystems
- Hedgehog signaling is restricted to the stromal compartment during pancreatic carcinogenesis
- (2009) H. Tian et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A paracrine requirement for hedgehog signalling in cancer
- (2008) Robert L. Yauch et al. NATURE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now