A combined ligand- and structure-based approach for the identification of rilmenidine-derived compounds which synergize the antitumor effects of doxorubicin

Published 2016 View Full Article

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Title
A combined ligand- and structure-based approach for the identification of rilmenidine-derived compounds which synergize the antitumor effects of doxorubicin
Authors
Keywords
Drug design, Synthesis, Rilmenidine, Doxorubicin synergism, α, 2, -Adrenoceptors, Cytotoxic activity, Apoptosis
Journal
BIOORGANIC & MEDICINAL CHEMISTRY
Volume 24, Issue 14, Pages 3174-3183
Publisher
Elsevier BV
Online
2016-05-25
DOI
10.1016/j.bmc.2016.05.043

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