Synthesis and biological evaluation of 1,2-dithiol-3-thiones and pyrrolo[1,2-a]pyrazines as novel hypoxia inducible factor-1 (HIF-1) inhibitor

Title
Synthesis and biological evaluation of 1,2-dithiol-3-thiones and pyrrolo[1,2-a]pyrazines as novel hypoxia inducible factor-1 (HIF-1) inhibitor
Authors
Keywords
Hypoxia inducible factor-1, VEGF, GLUT-1, Oltipraz, Pyrrolopyrazine
Journal
BIOORGANIC & MEDICINAL CHEMISTRY
Volume 24, Issue 12, Pages 2843-2851
Publisher
Elsevier BV
Online
2016-05-04
DOI
10.1016/j.bmc.2016.04.054

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