Glycerol induces G6pc in primary mouse hepatocytes and is the preferred substrate for gluconeogenesis both in vitro and in vivo
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Glycerol induces G6pc in primary mouse hepatocytes and is the preferred substrate for gluconeogenesis both in vitro and in vivo
Authors
Keywords
-
Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 294, Issue 48, Pages 18017-18028
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2019-10-24
DOI
10.1074/jbc.ra119.011033
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- PGC1A regulates the IRS1:IRS2 ratio during fasting to influence hepatic metabolism downstream of insulin
- (2019) Aurèle Besse-Patin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hepatocyte-specific HIF-1α ablation improves obesity-induced glucose intolerance by reducing first-pass GLP-1 degradation
- (2019) Yun Sok Lee et al. Science Advances
- Targeting hepatic glutaminase activity to ameliorate hyperglycemia
- (2018) Russell A Miller et al. NATURE MEDICINE
- Chemical genetic-based phenotypic screen reveals novel regulators of gluconeogenesis in human primary hepatocytes
- (2018) Haixia Zou et al. npj Genomic Medicine
- Butyrate stimulates hepatic gluconeogenesis in mouse primary hepatocytes
- (2018) Xueying Ji et al. Experimental and Therapeutic Medicine
- Cafeteria Diet Feeding in Young Rats Leads to Hepatic Steatosis and Increased Gluconeogenesis under Fatty Acids and Glucagon Influence
- (2018) Antonio Maeda Júnior et al. Nutrients
- Functional properties of hepatocytes in vitro are correlated with cell polarity maintenance
- (2017) Anja Zeigerer et al. EXPERIMENTAL CELL RESEARCH
- Glucose feeds the TCA cycle via circulating lactate
- (2017) Sheng Hui et al. NATURE
- Regulation of hepatic glucose metabolism in health and disease
- (2017) Max C. Petersen et al. Nature Reviews Endocrinology
- Importance of Hepatocyte Nuclear Factor 4α in Glycerol-induced Glucose-6-phosphatase Expression in Liver
- (2016) Mitsuhiko YOSHIDA et al. BIOMEDICAL RESEARCH-TOKYO
- Liver glucose metabolism in humans
- (2016) M. M. Adeva-Andany et al. BIOSCIENCE REPORTS
- Hepatic Mitochondrial Pyruvate Carrier 1 Is Required for Efficient Regulation of Gluconeogenesis and Whole-Body Glucose Homeostasis
- (2015) Lawrence R. Gray et al. Cell Metabolism
- Acetyl-CoA and the regulation of metabolism: mechanisms and consequences
- (2015) Lei Shi et al. CURRENT OPINION IN CELL BIOLOGY
- Fatty Acids, Obesity and Insulin Resistance
- (2015) Peter Arner et al. Obesity Facts
- DEoptim: AnRPackage for Global Optimization by Differential Evolution
- (2015) Katharine Mullen et al. Journal of Statistical Software
- Approach to assessing determinants of glucose homeostasis in the conscious mouse
- (2014) Curtis C. Hughey et al. MAMMALIAN GENOME
- Comprehensive review on lactate metabolism in human health
- (2014) M. Adeva-Andany et al. MITOCHONDRION
- Association between serum free fatty acid levels and nonalcoholic fatty liver disease: a cross-sectional study
- (2014) Juanwen Zhang et al. Scientific Reports
- Mechanism linking diabetes mellitus and obesity
- (2014) Abdullah Algoblan et al. Diabetes Metabolic Syndrome and Obesity-Targets and Therapy
- Relation Between Serum Free Fatty Acids and Adiposity, Insulin Resistance, and Cardiovascular Risk Factors From Adolescence to Adulthood
- (2013) Brigitte I. Frohnert et al. DIABETES
- Glycerol and Fatty Acids in Serum Predict the Development of Hyperglycemia and Type 2 Diabetes in Finnish Men
- (2013) Y. Mahendran et al. DIABETES CARE
- Fatty acids-stress attenuates gluconeogenesis induction and glucose production in primary hepatocytes
- (2012) Noga Budick-Harmelin et al. Lipids in Health and Disease
- Metabolomic Analysis and Visualization Engine for LC−MS Data
- (2010) Eugene Melamud et al. ANALYTICAL CHEMISTRY
- Glucose-6-phosphatase Catalytic Subunit Gene Family
- (2009) John C. Hutton et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Fasting hyperglycemia is not associated with increased expression of PEPCK or G6Pc in patients with Type 2 Diabetes
- (2009) V. T. Samuel et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structure, mechanism and regulation of pyruvate carboxylase
- (2008) Sarawut Jitrapakdee et al. BIOCHEMICAL JOURNAL
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started