Enhanced acyl-CoA:cholesterol acyltransferase activity increases cholesterol levels on the lipid droplet surface and impairs adipocyte function

The biogenesis of lipid droplets: Lipids take center stage

(2019) Mingming Gao et al.   PROGRESS IN LIPID RESEARCH

In vitro exploration of ACAT contributions to lipid droplet formation during adipogenesis

(2018) Yuyan Zhu et al.   JOURNAL OF LIPID RESEARCH

Interplay between Membrane Curvature and Cholesterol: Role of Palmitoylated Caveolin-1

(2018) Anjali Krishna et al.   BIOPHYSICAL JOURNAL

ORP2 Delivers Cholesterol to the Plasma Membrane in Exchange for Phosphatidylinositol 4, 5-Bisphosphate (PI(4,5)P2)

(2018) Huan Wang et al.   MOLECULAR CELL

Cholesterol and fatty acids regulate cysteine ubiquitylation of ACAT2 through competitive oxidation

(2017) Yong-Jian Wang et al.   NATURE CELL BIOLOGY

Advances on the Transfer of Lipids by Lipid Transfer Proteins

(2017) Louise H. Wong et al.   TRENDS IN BIOCHEMICAL SCIENCES

The ACAT2 expression of human leukocytes is responsible for the excretion of lipoproteins containing cholesteryl/steryl esters

(2016) Dongqing Guo et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Adipose tissue deficiency results in severe hyperlipidemia and atherosclerosis in the low-density lipoprotein receptor knockout mice

(2016) Mengyu Wang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

The counterflow transport of sterols and PI4P

(2016) Bruno Mesmin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Fat-specific Protein 27 (FSP27) Interacts with Adipose Triglyceride Lipase (ATGL) to Regulate Lipolysis and Insulin Sensitivity in Human Adipocytes

(2014) Tan Hooi Min Grahn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Caveolae as plasma membrane sensors, protectors and organizers

(2013) Robert G. Parton et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Pref-1, a Gatekeeper of Adipogenesis

(2013) Carolyn S. Hudak et al.   Frontiers in Endocrinology

Controlling the size of lipid droplets: lipid and protein factors

(2012) Hongyuan Yang et al.   CURRENT OPINION IN CELL BIOLOGY

Tissue-specific knockouts of ACAT2 reveal that intestinal depletion is sufficient to prevent diet-induced cholesterol accumulation in the liver and blood

(2012) Jun Zhang et al.   JOURNAL OF LIPID RESEARCH

Lipid Exchange Mechanism of the Cholesteryl Ester Transfer Protein Clarified by Atomistic and Coarse-grained Simulations

(2012) Artturi Koivuniemi et al.   PLoS Computational Biology

Cholesterol-Dependent Degradation of Squalene Monooxygenase, a Control Point in Cholesterol Synthesis beyond HMG-CoA Reductase

(2011) Saloni Gill et al.   Cell Metabolism

Insulin effects in muscle and adipose tissue

(2011) George Dimitriadis et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

A role for oxysterol-binding protein–related protein 5 in endosomal cholesterol trafficking

(2011) Ximing Du et al.   JOURNAL OF CELL BIOLOGY

Fsp27 promotes lipid droplet growth by lipid exchange and transfer at lipid droplet contact sites

(2011) Jingyi Gong et al.   JOURNAL OF CELL BIOLOGY

Cholesterol esterification by ACAT2 is essential for efficient intestinal cholesterol absorption: evidence from thoracic lymph duct cannulation

(2011) Tam M. Nguyen et al.   JOURNAL OF LIPID RESEARCH

Recent trends of body mass index distribution among school children in Sendai, Japan: Decrease of the prevalence of overweight and obesity, 2003–2009

(2010) Naoyuki Kurokawa et al.   Obesity Research & Clinical Practice

Acyl-coenzyme A:cholesterol acyltransferases

(2009) Ta-Yuan Chang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The LDL Receptor

(2009) Joseph L. Goldstein et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Perilipin Controls Lipolysis by Regulating the Interactions of AB-hydrolase Containing 5 (Abhd5) and Adipose Triglyceride Lipase (Atgl)

(2009) James G. Granneman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

OSBP-related protein 2 is a sterol receptor on lipid droplets that regulates the metabolism of neutral lipids

(2009) Riikka Hynynen et al.   JOURNAL OF LIPID RESEARCH

Feedback regulation of cholesterol synthesis: sterol-accelerated ubiquitination and degradation of HMG CoA reductase

(2008) Russell A DeBose-Boyd   CELL RESEARCH

Targeted Depletion of Hepatic ACAT2-driven Cholesterol Esterification Reveals a Non-biliary Route for Fecal Neutral Sterol Loss

(2008) J. Mark Brown et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FSP27 contributes to efficient energy storage in murine white adipocytes by promoting the formation of unilocular lipid droplets

(2008) Naonobu Nishino et al.   JOURNAL OF CLINICAL INVESTIGATION