Silencing transcription factor FOXM1 represses proliferation, migration, and invasion while inducing apoptosis of liver cancer stem cells by regulating the expression of ALDH2

Different Effects of Knockouts in ALDH 2 and ACSS 2 on Embryonic Stem Cell Differentiation

(2019) Ryan N. Serio et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Transcriptome analysis and prognosis of ALDH isoforms in human cancer

(2018) Peter Mu-Hsin Chang et al.   Scientific Reports

A Personalized Medicine Approach for Asian Americans with the Aldehyde Dehydrogenase 2*2 Variant

(2015) Eric R. Gross et al.   Annual Review of Pharmacology and Toxicology

Cancer stem cells in hepatocellular carcinoma: Therapeutic implications based on stem cell biology

(2015) Tetsuhiro Chiba et al.   HEPATOLOGY RESEARCH

The transcription factor Foxm1 is essential for the quiescence and maintenance of hematopoietic stem cells

(2015) Yu Hou et al.   NATURE IMMUNOLOGY

ALDH2(E487K) mutation increases protein turnover and promotes murine hepatocarcinogenesis

(2015) Shengfang Jin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comparison of clinicopathological parameters with FoxM1 expression in renal cell carcinoma

(2015) Sezen Kocarslan et al.   Journal of Cancer Research and Therapeutics

FOXM1: A key oncofoetal transcription factor in health and disease

(2014) Laura Bella et al.   SEMINARS IN CANCER BIOLOGY

Standing Out from the Crowd: Cancer Stem Cells in Hepatocellular Carcinoma

(2013) Bruno Sainz et al.   CANCER CELL

Foxm1 transcription factor is required for lung fibrosis and epithelial-to-mesenchymal transition

(2013) David Balli et al.   EMBO JOURNAL

The roles of FOXM1 in pancreatic stem cells and carcinogenesis

(2013) Ming Quan et al.   Molecular Cancer

FoxM1 Is Associated with Poor Prognosis of Non-Small Cell Lung Cancer Patients through Promoting Tumor Metastasis

(2013) Nuo Xu et al.   PLoS One

Coexpression of Stemness Factors Oct4 and Nanog Predict Liver Resection

(2012) Xin Yin et al.   ANNALS OF SURGICAL ONCOLOGY

OV6+ tumor-initiating cells contribute to tumor progression and invasion in human hepatocellular carcinoma

(2012) Wen Yang et al.   JOURNAL OF HEPATOLOGY

Upregulated FoxM1 expression induced by hepatitis B virus X protein promotes tumor metastasis and indicates poor prognosis in hepatitis B virus-related hepatocellular carcinoma

(2012) Limin Xia et al.   JOURNAL OF HEPATOLOGY

Hepatic stem cells and transforming growth factor β in hepatocellular carcinoma

(2012) Avijit Majumdar et al.   Nature Reviews Gastroenterology & Hepatology

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

FoxM1 Promotes β-Catenin Nuclear Localization and Controls Wnt Target-Gene Expression and Glioma Tumorigenesis

(2011) Nu Zhang et al.   CANCER CELL

Endothelial Cell-Specific Deletion of Transcription Factor FoxM1 Increases Urethane-Induced Lung Carcinogenesis

(2011) D. Balli et al.   CANCER RESEARCH

FoxM1 in Tumorigenicity of the Neuroblastoma Cells and Renewal of the Neural Progenitors

(2011) Z. Wang et al.   CANCER RESEARCH

Multiple faces of FoxM1 transcription factor

(2011) Tanya V. Kalin et al.   CELL CYCLE

CD24+ Liver Tumor-Initiating Cells Drive Self-Renewal and Tumor Initiation through STAT3-Mediated NANOG Regulation

(2011) Terence Kin Wah Lee et al.   Cell Stem Cell

The enzymatic activity of human aldehyde dehydrogenases 1A2 and 2 (ALDH1A2 and ALDH2) is detected by Aldefluor, inhibited by diethylaminobenzaldehyde and has significant effects on cell proliferation and drug resistance

(2011) Jan S. Moreb et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Role of Sox2 and Oct4 in predicting survival of hepatocellular carcinoma patients after hepatectomy

(2011) Pinzhu Huang et al.   CLINICAL BIOCHEMISTRY

Over-expression of FoxM1 leads to epithelial-mesenchymal transition and cancer stem cell phenotype in pancreatic cancer cells

(2011) Bin Bao et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Aldehyde Dehydrogenase 1 A1-Positive Cell Population Is Enriched in Tumor-Initiating Cells and Associated with Progression of Bladder Cancer

(2010) Y. Su et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Aldehyde Dehydrogenase Activity Selects for Lung Adenocarcinoma Stem Cells Dependent on Notch Signaling

(2010) J. P. Sullivan et al.   CANCER RESEARCH

Induction of Human Epithelial Stem/Progenitor Expansion by FOXM1

(2010) E. Gemenetzidis et al.   CANCER RESEARCH

The FOXM1 transcriptional factor promotes the proliferation of leukemia cells through modulation of cell cycle progression in acute myeloid leukemia

(2010) S. Nakamura et al.   CARCINOGENESIS

CD13 is a therapeutic target in human liver cancer stem cells

(2010) Naotsugu Haraguchi et al.   JOURNAL OF CLINICAL INVESTIGATION

Foxm1 transcription factor is required for maintenance of pluripotency of P19 embryonal carcinoma cells

(2010) Zhongqiu Xie et al.   NUCLEIC ACIDS RESEARCH

A selective ALDH-2 inhibitor reduces anxiety in rats

(2009) David H. Overstreet et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Toll-like receptor 4 mediates synergism between alcohol and HCV in hepatic oncogenesis involving stem cell marker Nanog

(2009) K. Machida et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Alcohol Flushing Response: An Unrecognized Risk Factor for Esophageal Cancer from Alcohol Consumption

(2009) Philip J Brooks et al.   PLOS MEDICINE

Significance of CD90+ Cancer Stem Cells in Human Liver Cancer

(2008) Zhen Fan Yang et al.   CANCER CELL

EpCAM-Positive Hepatocellular Carcinoma Cells Are Tumor-Initiating Cells With Stem/Progenitor Cell Features

(2008) Taro Yamashita et al.   GASTROENTEROLOGY

Aldehyde Dehydrogenase Discriminates the CD133 Liver Cancer Stem Cell Populations

(2008) S. Ma et al.   MOLECULAR CANCER RESEARCH