The Role of Sonic Hedgehog Signaling in the Tumor Microenvironment of Oral Squamous Cell Carcinoma

LRP6 ectodomain prevents SDF-1/CXCR4-induced breast cancer metastasis to lung

(2019) Jiankang Zhang et al.   CLINICAL CANCER RESEARCH

Role of Hedgehog Signaling in Vasculature Development, Differentiation, and Maintenance

(2019) Candice Chapouly et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Tumor Angiogenic Inhibition Triggered Necrosis (TAITN) in Oral Cancer

(2019) Saori Yoshida et al.   Cells

M1 macrophage recruitment correlates with worse outcome in SHH Medulloblastomas

(2018) Chanhee Lee et al.   BMC CANCER

Prognostic significance of the methylation of Wnt pathway antagonists—CXXC4, DACT2, and the inhibitors of sonic hedgehog signaling—ZIC1, ZIC4, and HHIP in head and neck squamous cell carcinomas

(2016) Jarosław Paluszczak et al.   Clinical Oral Investigations

Autocrine Sonic hedgehog signaling promotes gastric cancer proliferation through induction of phospholipase Cγ1 and the ERK1/2 pathway

(2016) Zhai Ertao et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Tumor-associated macrophages correlate with the clinicopathological features and poor outcomes via inducing epithelial to mesenchymal transition in oral squamous cell carcinoma

(2016) Yong Hu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

The Role of Sonic Hedgehog Signaling in Osteoclastogenesis and Jaw Bone Destruction

(2016) Tsuyoshi Shimo et al.   PLoS One

The sonic hedgehog signaling pathway stimulates anaplastic thyroid cancer cell motility and invasiveness by activating Akt and c-Met

(2016) Ashley J. Williamson et al.   Oncotarget

CXCR4 Expression is Associated with Poor Prognosis in Patients with Esophageal Squamous Cell Carcinoma

(2015) Masakazu Goto et al.   ANNALS OF SURGICAL ONCOLOGY

Immunohistochemical evaluation of hedgehog signalling in epithelial/mesenchymal interactions in squamous cell carcinoma transformation: a pilot study

(2015) Ana Cristina Gonzalez et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

Sonic hedgehog (Shh) signaling promotes tumorigenicity and stemness via activation of epithelial-to-mesenchymal transition (EMT) in bladder cancer

(2015) S.S. Islam et al.   MOLECULAR CARCINOGENESIS

A critical role of autocrine sonic hedgehog signaling in human CD138+ myeloma cell survival and drug resistance

(2014) Z. Liu et al.   BLOOD

Hedgehog Signaling Restrains Bladder Cancer Progression by Eliciting Stromal Production of Urothelial Differentiation Factors

(2014) Kunyoo Shin et al.   CANCER CELL

Sonic hedgehog signaling may promote invasion and metastasis of oral squamous cell carcinoma by activating MMP-9 and E-cadherin expression

(2014) Hai-Xia Fan et al.   MEDICAL ONCOLOGY

Functional polarization of tumour-associated macrophages by tumour-derived lactic acid

(2014) Oscar R. Colegio et al.   NATURE

The cellular and molecular origin of tumor-associated macrophages

(2014) R. A. Franklin et al.   SCIENCE

CXCL12-CXCR4 axis promotes the natural selection of breast cancer cell metastasis

(2014) Yanan Sun et al.   TUMOR BIOLOGY

Sonic Hedgehog signaling pathway in primary liver cancer cells

(2014) Lian-Yi Guo et al.   Asian Pacific Journal of Tropical Medicine

Clinical significance of macrophage heterogeneity in human malignant tumors

(2013) Yoshihiro Komohara et al.   CANCER SCIENCE

Expression of hedgehog signaling molecules as a prognostic indicator of oral squamous cell carcinoma

(2012) Yi-Fen Wang et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

Genome-Wide Screening Reveals an EMT Molecular Network Mediated by Sonic Hedgehog-Gli1 Signaling in Pancreatic Cancer Cells

(2012) Xuanfu Xu et al.   PLoS One

Impact of CD68/(CD3+CD20) Ratio at the Invasive Front of Primary Tumors on Distant Metastasis Development in Breast Cancer

(2012) Noemí Eiró et al.   PLoS One

Sonic Hedgehog Pathway Promotes Metastasis and Lymphangiogenesis via Activation of Akt, EMT, and MMP-9 Pathway in Gastric Cancer

(2011) Y. A. Yoo et al.   CANCER RESEARCH

A crucial requirement for Hedgehog signaling in small cell lung cancer

(2011) Kwon-Sik Park et al.   NATURE MEDICINE

Hedgehog signaling pathway mediates the progression of non-invasive breast cancer to invasive breast cancer

(2010) Masae Souzaki et al.   CANCER SCIENCE

Overexpression of Smoothened Activates the Sonic Hedgehog Signaling Pathway in Pancreatic Cancer-Associated Fibroblasts

(2010) K. Walter et al.   CLINICAL CANCER RESEARCH

CXCL12 (SDF-1)/CXCR4 Pathway in Cancer

(2010) B. A. Teicher et al.   CLINICAL CANCER RESEARCH

Fibroblast gene expression profile reflects the stage of tumour progression in oral squamous cell carcinoma

(2010) Kue Peng Lim et al.   JOURNAL OF PATHOLOGY

Blockade of hedgehog signaling pathway as a therapeutic strategy for pancreatic cancer

(2009) Fu-Guo Xu et al.   CANCER LETTERS

Human colon cancer epithelial cells harbour active HEDGEHOG-GLI signalling that is essential for tumour growth, recurrence, metastasis and stem cell survival and expansion

(2009) Frédéric Varnat et al.   EMBO Molecular Medicine

Hedgehog signalling in colon cancer and stem cells

(2009) Alberto Gulino et al.   EMBO Molecular Medicine

Sonic hedgehog derived from human pancreatic cancer cells augments angiogenic function of endothelial progenitor cells

(2008) Madoka Yamazaki et al.   CANCER SCIENCE

Aberrant activation of hedgehog signaling pathway in ovarian cancers: effect on prognosis, cell invasion and differentiation

(2008) Xiaoyun Liao et al.   CARCINOGENESIS

Role of Hedgehog Signaling in Ovarian Cancer

(2008) R. Bhattacharya et al.   CLINICAL CANCER RESEARCH

Sonic Hedgehog Promotes Desmoplasia in Pancreatic Cancer

(2008) J. M. Bailey et al.   CLINICAL CANCER RESEARCH