Ceftriaxone Treatment Affects EAAT2 Expression and Glutamatergic Neurotransmission and Exerts a Weak Anticonvulsant Effect in Young Rats

The role of astrocytic glutamate transporters GLT-1 and GLAST in neurological disorders: Potential targets for neurotherapeutics

(2019) Edward Pajarillo et al.   NEUROPHARMACOLOGY

Genetic and pharmacological manipulation of glial glutamate transporters does not alter infection-induced seizure activity

(2019) Jaycie L. Loewen et al.   EXPERIMENTAL NEUROLOGY

Transient Morphological Alterations in the Hippocampus After Pentylenetetrazole-Induced Seizures in Rats

(2018) Dmitry S. Vasilev et al.   NEUROCHEMICAL RESEARCH

Astrocytic Atrophy Following Status Epilepticus Parallels Reduced Ca2+ Activity and Impaired Synaptic Plasticity in the Rat Hippocampus

(2018) Alex Plata et al.   Frontiers in Molecular Neuroscience

GLT-1 Loss Accelerates Cognitive Deficit Onset in an Alzheimer's Disease Animal Model

(2018) Paramita Mookherjee et al.   JOURNAL OF ALZHEIMERS DISEASE

Alterations in mRNA expression of glutamate receptor subunits and excitatory amino acid transporters following pilocarpine-induced seizures in rats

(2018) Olga E. Zubareva et al.   NEUROSCIENCE LETTERS

Changes in Functional Properties of Rat Hippocampal Neurons Following Pentylenetetrazole-induced Status Epilepticus

(2018) Tatyana Y. Postnikova et al.   NEUROSCIENCE

Personalized translational epilepsy research — Novel approaches and future perspectives

(2017) Felix Rosenow et al.   EPILEPSY & BEHAVIOR

Evaluating the role of astrocytes on β-estradiol effect on seizures of Pilocarpine epileptic model

(2017) Masoumeh Sarfi et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Regulation of astrocyte glutamate transporter-1 (GLT1) and aquaporin-4 (AQP4) expression in a model of epilepsy

(2016) Jacqueline A. Hubbard et al.   EXPERIMENTAL NEUROLOGY

The importance of the excitatory amino acid transporter 3 (EAAT3)

(2016) Walden E. Bjørn-Yoshimoto et al.   NEUROCHEMISTRY INTERNATIONAL

Changes of AMPA receptor properties in the neocortex and hippocampus following pilocarpine-induced status epilepticus in rats

(2016) Sergey L. Malkin et al.   NEUROSCIENCE

N-Acetylcysteine and Ceftriaxone as Preconditioning Strategies in Focal Brain Ischemia: Influence on Glutamate Transporters Expression

(2016) Weronika Krzyzanowska et al.   NEUROTOXICITY RESEARCH

Effect of GLT-1 modulator and P2X7 antagonists alone and in combination in the kindling model of epilepsy in rats

(2015) Neha Soni et al.   EPILEPSY & BEHAVIOR

Positive effects of ceftriaxone on pentylenetetrazol-induced convulsion model in rats

(2015) Yigit Uyanikgil et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Epilepsy: new advances

(2015) Solomon L Moshé et al.   LANCET

Glutamate transporter splice variant expression in an enriched pyramidal cell population in schizophrenia

(2015) S M O'Donovan et al.   Translational Psychiatry

Small-molecule activator of glutamate transporter EAAT2 translation provides neuroprotection

(2014) Qiongman Kong et al.   JOURNAL OF CLINICAL INVESTIGATION

Ceftriaxone modulates uptake activity of glial glutamate transporter-1 against global brain ischemia in rats

(2014) Yu-Yan Hu et al.   JOURNAL OF NEUROCHEMISTRY

N-methyl-D-aspartate receptor channel blockers prevent pentylenetetrazole-induced convulsions and morphological changes in rat brain neurons

(2014) Aleksey V. Zaitsev et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Functional changes in glutamate transporters and astrocyte biophysical properties in a rodent model of focal cortical dysplasia

(2014) Susan L. Campbell et al.   Frontiers in Cellular Neuroscience

Astrocyte-Synapse Structural Plasticity

(2014) Yann Bernardinelli et al.   NEURAL PLASTICITY

Ceftriaxone Treatment after Traumatic Brain Injury Restores Expression of the Glutamate Transporter, GLT-1, Reduces Regional Gliosis, and Reduces Post-Traumatic Seizures in the Rat

(2013) Grant S. Goodrich et al.   JOURNAL OF NEUROTRAUMA

New avenues for anti-epileptic drug discovery and development

(2013) Wolfgang Löscher et al.   NATURE REVIEWS DRUG DISCOVERY

Time-dependent modulation of AMPA receptor phosphorylation and mRNA expression of NMDA receptors and glial glutamate transporters in the rat hippocampus and cerebral cortex in a pilocarpine model of epilepsy

(2013) Mark William Lopes et al.   EXPERIMENTAL BRAIN RESEARCH

Transforming growth factor-α mediates estrogen-induced upregulation of glutamate transporter GLT-1 in rat primary astrocytes

(2012) Eunsook Lee et al.   GLIA

Increased glial glutamate transporter EAAT2 expression reduces epileptogenic processes following pilocarpine-induced status epilepticus

(2012) Qiongman Kong et al.   NEUROBIOLOGY OF DISEASE

Inhibition of the slow afterhyperpolarization restores the classical spike timing-dependent plasticity rule obeyed in layer 2/3 pyramidal cells of the prefrontal cortex

(2011) Aleksey V. Zaitsev et al.   JOURNAL OF NEUROPHYSIOLOGY

Role of Excitatory Amino Acid Transporter-2 (EAAT2) and glutamate in neurodegeneration: Opportunities for developing novel therapeutics

(2010) Keetae Kim et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Global disparities in the epilepsy treatment gap: a systematic review

(2009) Ana-Claire Meyer et al.   BULLETIN OF THE WORLD HEALTH ORGANIZATION

Three-dimensional relationships between perisynaptic astroglia and human hippocampal synapses

(2009) Mark R. Witcher et al.   GLIA

Beneficial Effects of Ceftriaxone Against Pentylenetetrazole-Evoked Convulsions

(2008) Ankica V. Jelenkovic et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Mechanism of Ceftriaxone Induction of Excitatory Amino Acid Transporter-2 Expression and Glutamate Uptake in Primary Human Astrocytes

(2008) Seok-Geun Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The β-lactam antibiotic, ceftriaxone, dramatically improves survival, increases glutamate uptake and induces neurotrophins in stroke

(2008) Christa Thöne-Reineke et al.   JOURNAL OF HYPERTENSION

Decreased glutamate transport enhances excitability in a rat model of cortical dysplasia

(2008) Susan L. Campbell et al.   NEUROBIOLOGY OF DISEASE

Collapse of extracellular glutamate regulation during epileptogenesis: down-regulation and functional failure of glutamate transporter function in rats with chronic seizures induced by kainic acid

(2003) Yuto Ueda et al.   JOURNAL OF NEUROCHEMISTRY