Growth Plate Chondrocytes: Skeletal Development, Growth and Beyond

Slide-seq: A scalable technology for measuring genome-wide expression at high spatial resolution

(2019) Samuel G. Rodriques et al.   SCIENCE

A radical switch in clonality reveals a stem cell niche in the epiphyseal growth plate

(2019) Phillip T. Newton et al.   NATURE

Growth plate borderline chondrocytes behave as transient mesenchymal precursor cells

(2019) Koji Mizuhashi et al.   JOURNAL OF BONE AND MINERAL RESEARCH

The Unmixing Problem: A Guide to Applying Single-Cell RNA Sequencing to Bone

(2019) Matthew B Greenblatt et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Resting zone of the growth plate houses a unique class of skeletal stem cells

(2018) Koji Mizuhashi et al.   NATURE

Identification and Specification of the Mouse Skeletal Stem Cell

(2015) Charles K.F. Chan et al.   CELL

The transcription factor Foxc1 is necessary for Ihh–Gli2-regulated endochondral ossification

(2015) Michiko Yoshida et al.   Nature Communications

FGFR3 Deficiency Causes Multiple Chondroma-like Lesions by Upregulating Hedgehog Signaling

(2015) Siru Zhou et al.   PLoS Genetics

Identification of aPrg4-Expressing Articular Cartilage Progenitor Cell Population in Mice

(2015) Elena Kozhemyakina et al.   Arthritis & Rheumatology

Wnt and the Wnt signaling pathway in bone development and disease

(2014) Yiping Wang   Frontiers in Bioscience-Landmark

Epiphyseal Chondrocyte Secondary Ossification Centers Require Thyroid Hormone Activation of Indian Hedgehog and Osterix Signaling

(2014) Weirong Xing et al.   JOURNAL OF BONE AND MINERAL RESEARCH

A subset of chondrogenic cells provides early mesenchymal progenitors in growing bones

(2014) Noriaki Ono et al.   NATURE CELL BIOLOGY

Hypertrophic chondrocytes can become osteoblasts and osteocytes in endochondral bone formation

(2014) L. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of GH/IGF-1 on Bone Metabolism and Osteoporsosis

(2014) Vittorio Locatelli et al.   International Journal of Endocrinology

Chondrocytes Transdifferentiate into Osteoblasts in Endochondral Bone during Development, Postnatal Growth and Fracture Healing in Mice

(2014) Xin Zhou et al.   PLoS Genetics

Hedgehog-Gli Activators Direct Osteo-chondrogenic Function of Bone Morphogenetic Protein toward Osteogenesis in the Perichondrium

(2013) Hironori Hojo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multiple phases of chondrocyte enlargement underlie differences in skeletal proportions

(2013) Kimberly L. Cooper et al.   NATURE

Activation of Hedgehog signaling by loss of GNAS causes heterotopic ossification

(2013) Jean B Regard et al.   NATURE MEDICINE

Gli1 Protein Participates in Hedgehog-mediated Specification of Osteoblast Lineage during Endochondral Ossification

(2012) Hironori Hojo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IGF-1R signaling in chondrocytes modulates growth plate development by interacting with the PTHrP/Ihh pathway

(2011) Yongmei Wang et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Smad6 is essential to limit BMP signaling during cartilage development

(2011) Kristine D Estrada et al.   JOURNAL OF BONE AND MINERAL RESEARCH

BMP2, but not BMP4, is crucial for chondrocyte proliferation and maturation during endochondral bone development

(2011) B. Shu et al.   JOURNAL OF CELL SCIENCE

Osteoblast Precursors, but Not Mature Osteoblasts, Move into Developing and Fractured Bones along with Invading Blood Vessels

(2010) Christa Maes et al.   DEVELOPMENTAL CELL

The Wnt/β-Catenin Pathway Interacts Differentially with PTHrP Signaling to Control Chondrocyte Hypertrophy and Final Maturation

(2009) Xizhi Guo et al.   PLoS One

Indian hedgehog signals independently of PTHrP to promote chondrocyte hypertrophy

(2008) K. K. Mak et al.   DEVELOPMENT

Hedgehog Signaling in Development and Cancer

(2008) Jin Jiang et al.   DEVELOPMENTAL CELL