Hyperthermia and immunotherapy: clinical opportunities

Radiation Therapy and Immune Modulation

(2019) Jonathan E. Leeman et al.   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

Iron Nanoparticles for Low-power Local Magnetic Hyperthermia in Combination with Immune Checkpoint Blockade for Systemic Antitumor Therapy

(2019) Yu Chao et al.   NANO LETTERS

Validation of a Genomic Risk Classifier to Predict Prostate Cancer-specific Mortality in Men with Adverse Pathologic Features

(2018) R. Jeffrey Karnes et al.   EUROPEAN UROLOGY

Radiation therapy and immunotherapy: what is the optimal timing or sequencing?

(2018) Maureen L Aliru et al.   Immunotherapy

LBA8_PRKEYNOTE-048: Phase III study of first-line pembrolizumab (P) for recurrent/metastatic head and neck squamous cell carcinoma (R/M HNSCC)

(2018) B Burtness et al.   ANNALS OF ONCOLOGY

Radiation, Immune Checkpoint Blockade and the Abscopal Effect: A Critical Review on Timing, Dose and Fractionation

(2018) Zachary S. Buchwald et al.   Frontiers in Oncology

Genomic Classifier Augments the Role of Pathological Features in Identifying Optimal Candidates for Adjuvant Radiation Therapy in Patients With Prostate Cancer: Development and Internal Validation of a Multivariable Prognostic Model

(2017) Deepansh Dalela et al.   JOURNAL OF CLINICAL ONCOLOGY

Atezolizumab in patients with locally advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy: a single-arm, multicentre, phase 2 trial

(2016) Jonathan E Rosenberg et al.   LANCET

Safety and clinical activity of pembrolizumab for treatment of recurrent or metastatic squamous cell carcinoma of the head and neck (KEYNOTE-012): an open-label, multicentre, phase 1b trial

(2016) Tanguy Y Seiwert et al.   LANCET ONCOLOGY

Nivolumab for Recurrent Squamous-Cell Carcinoma of the Head and Neck

(2016) Robert L. Ferris et al.   NEW ENGLAND JOURNAL OF MEDICINE

Local hyperthermia combined with radiotherapy and-/or chemotherapy: Recent advances and promises for the future

(2015) N.R. Datta et al.   CANCER TREATMENT REVIEWS

Pembrolizumab versus investigator-choice chemotherapy for ipilimumab-refractory melanoma (KEYNOTE-002): a randomised, controlled, phase 2 trial

(2015) Antoni Ribas et al.   LANCET ONCOLOGY

Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): a randomised, controlled, open-label, phase 3 trial

(2015) Jeffrey S Weber et al.   LANCET ONCOLOGY

Nivolumab in Previously Untreated Melanoma without BRAF Mutation

(2015) Caroline Robert et al.   NEW ENGLAND JOURNAL OF MEDICINE

Nivolumab and Ipilimumab versus Ipilimumab in Untreated Melanoma

(2015) Michael A. Postow et al.   NEW ENGLAND JOURNAL OF MEDICINE

Pembrolizumab versus Ipilimumab in Advanced Melanoma

(2015) Caroline Robert et al.   NEW ENGLAND JOURNAL OF MEDICINE

Effects of hyperthermia on DNA repair pathways: one treatment to inhibit them all

(2015) Arlene L. Oei et al.   Radiation Oncology

Expanding the use of monoclonal antibody therapy of cancer by using ionising radiation to upregulate antibody targets

(2014) M M Wattenberg et al.   BRITISH JOURNAL OF CANCER

Local tumour hyperthermia as immunotherapy for metastatic cancer

(2014) Seiko Toraya-Brown et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

MPDL3280A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancer

(2014) Thomas Powles et al.   NATURE

Hyperthermia, Radiation and Chemotherapy: The Role of Heat in Multidisciplinary Cancer Care

(2014) Mark Hurwitz et al.   SEMINARS IN ONCOLOGY

Temperature Matters! And Why It Should Matter to Tumor Immunologists

(2013) E. A. Repasky et al.   Cancer Immunology Research

Mild Elevation of Body Temperature Reduces Tumor Interstitial Fluid Pressure and Hypoxia and Enhances Efficacy of Radiotherapy in Murine Tumor Models

(2011) A. Sen et al.   CANCER RESEARCH

Long-term outcomes of a randomized controlled trial comparing thermochemotherapy with mitomycin-C alone as adjuvant treatment for non-muscle-invasive bladder cancer (NMIBC)

(2010) Renzo Colombo et al.   BJU INTERNATIONAL

A phase I/II study of neoadjuvant liposomal doxorubicin, paclitaxel, and hyperthermia in locally advanced breast cancer

(2010) Zeljko Vujaskovic et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

(2010) F. Stephen Hodi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Fractionated but Not Single-Dose Radiotherapy Induces an Immune-Mediated Abscopal Effect when Combined with Anti-CTLA-4 Antibody

(2009) M. Z. Dewan et al.   CLINICAL CANCER RESEARCH

Platinum-Based Chemotherapy plus Cetuximab in Head and Neck Cancer

(2008) Jan B. Vermorken et al.   NEW ENGLAND JOURNAL OF MEDICINE