Article
Chemistry, Analytical
Marius Andrei Olariu, Tudor Alexandru Filip, Catalina Anisoara Peptu, Ina Turcan
Summary: This paper reports the functionality of dielectrophoresis (DEP) for manipulating multi-walled carbon nanotubes (MWCNTs) on printed interdigitated electrodes. The success of DEP manipulation and suitable signal frequencies for avoiding parasitic effects were demonstrated. The time-dependent effect and voltage contribution in MWCNTs bridge formation were discussed.
Article
Mechanics
Ye Tao, Weiyu Liu, Zhenyou Ge, Bobin Yao, Yukun Ren
Summary: This paper proposes a unique method called insulator-decorated bipolar electrochemistry(IDBE) for large-scale separation of bioparticles in microchannels using AC dielectrophoresis (DEP). By extending the range of DEP force field, the IDBE method enables highly efficient separation of live and dead yeast cells in a microchip.
Article
Computer Science, Information Systems
Alia Mohammed Shaker Alblooshi, Fadi Alnaimat, Bobby Mathew
Summary: This paper presents a mathematical model of a dielectrophoretic microdevice with planar corrugated electrodes for focusing micro-particles in a micro-scale flow passage. The model considers various phenomena influencing particle focusing and parametric study reveals the dependence of performance metrics on geometric and operating parameters. The model allows for determining desired performance metrics based on constraints and is validated using experimental data.
Article
Biochemical Research Methods
Kazuma Yoda, Yoshiyasu Ichikawa, Masahiro Motosuke
Summary: This paper presents a newly developed high-throughput measurement device for determining the dielectric properties of cancer cells. The device utilizes continuous-flow electrorotation to measure the rotational behavior of cells, resulting in a significant improvement in throughput compared to conventional devices.
Article
Automation & Control Systems
Xueliang Zhang, Julong Yuan, Qianfa Deng, Xu Wang, Yingyuan Luo
Summary: The key to the high-speed abrasive flow composite polishing method is based on the dielectrophoresis effect, which can significantly improve polishing efficiency and reduce polishing time, showing important application potential for compound polishing.
INTERNATIONAL JOURNAL OF ADVANCED MANUFACTURING TECHNOLOGY
(2022)
Article
Chemistry, Analytical
Yameng Liu, Mark A. Hayes
Summary: Proteins are complex and difficult to analyze, but dielectrophoresis can be used to characterize and concentrate them. Forces exerted on different proteins are larger than predicted by traditional theory, leading to more effective separation and concentration.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Felix Pfisterer, Neus Godino, Tobias Gerling, Michael Kirschbaum
Summary: In this study, a microfluidic flow protocol for selective electroporation of predefined target cells identified in real-time by high-quality microscopic image analysis was presented. This method allows selective poration of target cells while non-target cells remain unaffected in heterogeneous cell samples.
Review
Chemistry, Multidisciplinary
A. Tanwar, H. A. Gandhi, D. Kushwaha, J. Bhattacharya
Summary: Biosensors are important tools for detecting and quantitatively analyzing biomolecules and chemical compounds. Microelectrode arrays (MEAs) are widely used biosensing devices that detect changes in current, impedance, and potential. This review discusses different MEAs and the techniques used for their fabrication, as well as recent applications.
MATERIALS TODAY CHEMISTRY
(2022)
Article
Chemistry, Analytical
Mohammad K. D. Manshadi, Amin Mansoorifar, Jung-Chih Chiao, Ali Beskok
Summary: This study introduces inexpensive, rapid, sensitive, and quantifiable impedance-based immunosensors to evaluate the concentration of neutralizing antibodies (NAb) against the coronavirus. The sensor detection mechanism is mainly based on the diffusion of biomolecules onto the electrode surface. The results demonstrate that the sensor is capable of detecting NAb in the range of 45 ng/mL to 185 ng/mL. Due to its fast test results and lower costs, this sensor can be used to assess NAb in people's blood serum before receiving further COVID vaccine doses.
ANALYTICAL CHEMISTRY
(2023)
Article
Physics, Applied
Minh-Thang Hoang, Nishant Deshmukh, Amar T. Mohabir, Leonard C. Feldman, Michael A. Filler, Jerry W. Shan
Summary: Doped semiconductor nanowires are important for next-generation electronic colloidal materials. This study quantitatively measures the permanent dipoles of pn nanowires and investigates their origin, showing that they originate from non-uniform surface-charge distributions rather than internal charges at the p-n junction. This understanding has relevance to the manipulation, assembly, characterization, and separation of nanowire electronics by electric fields.
APPLIED PHYSICS LETTERS
(2023)
Article
Chemistry, Multidisciplinary
Hanfei Li, Fei Han, Lulu Wang, Laixin Huang, Oluwarotimi Williams Samuel, Hang Zhao, Ruijie Xie, Ping Wang, Qiong Tian, Qingsong Li, Yang Zhao, Mei Yu, Jing Sun, Ruofan Yang, Xiaomeng Zhou, Fei Li, Guanglin Li, Yi Lu, Peizhi Guo, Zhiyuan Liu
Summary: A hybrid strategy is reported to prepare ultra-narrow multi-channel stretchable microelectrodes without using photolithography or laser-assisting etching. A 10 μm x 10 μm monitoring window is fabricated with enhanced interfacial impedance by the special rough surface. The stretchable microelectrodes can detect electrophysiological signals of single cells in vitro and collect electrophysiological signals more precisely in vivo.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Mechanics
Raul Fernandez-Mateo, Hywel Morgan, Antonio Ramos, Pablo Garcia-Sanchez
Summary: We experimentally investigate the repulsion between charged microscopic particles and the channel walls during electrophoresis in microfluidic devices. This repulsion is primarily caused by hydrodynamic interactions arising from flow vortices induced by the slip velocity on the particle surface due to the electric field. Measurement of wall-particle separation allows us to infer the maximum slip velocity on the particle surface, including very small velocities that are otherwise difficult to directly measure. The data at low electric field amplitudes agree with theoretical predictions based on Concentration Polarization Electro-osmosis (CPEO), but the predictions of CPEO theory break down for higher electric fields. Furthermore, we show that strong electric fields can disrupt the quadrupolar flow structures, leading to a weaker wall repulsion.
Article
Engineering, Electrical & Electronic
Yun-Sheng Chan, Ting-Ting Hsu, Yi-Po Chen, Hsu-Min Wu, Yun-Ming Wang, Chen-Yi Lee
Summary: This brief introduces a lab-on-a-chip for cancer cell manipulation and separation. The chip utilizes a programmable microelectrode dot array with 115,200 sub-microelectrodes to generate a traveling wave electric field. Experimental results demonstrate that the chip can manipulate MDA-MB-231 cells and HELA cells at high speeds under low applied voltage.
IEEE TRANSACTIONS ON CIRCUITS AND SYSTEMS II-EXPRESS BRIEFS
(2022)
Article
Engineering, Biomedical
Jongcheon Lim, Calvin D. Eiber, Anina Sun, Amanda Maples, Terry L. Powley, Matthew P. Ward, Hyowon Lee
Summary: This study compared the neural stimulation performance of fractal microelectrodes and circle microelectrodes, finding that fractal microelectrodes require 52% less energy to activate C-fibers compared to circle microelectrodes. This is the first demonstration of the geometric advantage of fractal microelectrodes for vagus nerve stimulation in vivo.
ADVANCED HEALTHCARE MATERIALS
(2023)
Article
Electrochemistry
Chao Tan, Haocheng Yin, Victoria Brooks, Prabhu U. Arumugam, Shabnam Siddiqui
Summary: This study presents a systematic investigation of the application of electrochemically roughened platinum microelectrodes for glutamate detection. The experimental results show that the treated microelectrodes have increased surface roughness and electroactive area, decreased charge transfer resistance, and improved selectivity and sensitivity. An impedance model is proposed to explain the microstructural and electrochemical property changes of the roughened microelectrodes. This research provides a foundation for designing enhanced biosensors for neurotransmitter detection.
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
(2022)
