Article
Nutrition & Dietetics
Giulia Collatuzzo, Eva Negri, Claudio Pelucchi, Rossella Bonzi, Federica Turati, Charles S. Rabkin, Linda M. Liao, Rashmi Sinha, Domenico Palli, Monica Ferraroni, Lizbeth Lopez-Carrillo, Nuno Lunet, Samantha Morais, Demetrius Albanes, Stephanie J. Weinstein, Dominick Parisi, David Zaridze, Dmitry Maximovitch, Trinidad Dierssen-Sotos, Jose Juan Jimenez-Moleon, Jesus Vioque, Manoli Garcia de la Hera, Maria Paula Curado, Emmanuel Dias-Neto, Raul Ulises Hernandez-Ramirez, Malaquias Lopez-Cervantes, Mary H. Ward, Shoichiro Tsugane, Akihisa Hidaka, Areti Lagiou, Pagona Lagiou, Zuo-Feng Zhang, Antonia Trichopoulou, Anna Karakatsani, Maria Constanza Camargo, Carlo La Vecchia, Paolo Boffetta
Summary: A meta-analysis of 16 studies found no significant association between yoghurt consumption and gastric cancer risk.
Article
Nutrition & Dietetics
Sara Moazzen, Francisco O. Cortes-Ibanez, Bert van der Vegt, Behrooz Z. Alizadeh, Geertruida H. de Bock
Summary: The study found that high scores on the American Cancer Society (ACS) Index were significantly associated with a reduced risk of colorectal cancer, but high dietary index scores did not show strong beneficial effects on upper gastrointestinal cancer risk.
EUROPEAN JOURNAL OF NUTRITION
(2022)
Article
Gastroenterology & Hepatology
Samantha Morais, Adriana Costa, Gabriela Albuquerque, Natalia Araujo, Shoichiro Tsugane, Akihisa Hidaka, Gerson Shigueaki Hamada, Weimin Ye, Amelie Plymoth, Marcis Leja, Evita Gasenko, David Zaridze, Dmitry Maximovich, Reza Malekzadeh, Mohammad H. Derakhshan, Claudio Pelucchi, Eva Negri, M. Constanza Camargo, Maria Paula Curado, Jesus Vioque, Zuo-Feng Zhang, Carlo La Vecchia, Paolo Boffetta, Nuno Lunet
Summary: This study quantified the association between H. pylori infection and NCGC, finding a stronger link after reclassifying negative infection cases. Results were consistent across demographics, clinical features, and lifestyle factors, with a notable geographic variation in the association, especially in Asian studies.
Article
Oncology
Laura Alvarez-Alvarez, Facundo Vitelli-Storelli, Maria Rubin-Garcia, Nuria Aragones, Eva Ardanaz, Gemma Castano-Vinyals, Mireia Obon-Santacana, Trinidad Dierssen-Sotos, Dolores Salas-Trejo, Adonina Tardon, Jose Juan Jimenez Moleon, Juan Alguacil, Maria Dolores Chirlaque, Beatriz Perez-Gomez, Marina Pollan, Manolis Kogevinas, Vicente Martin
Summary: Adherence to a Mediterranean diet pattern is a protective factor for the risk of gastric cancer, with higher adherence associated with greater protection, particularly against non-cardia and intestinal types of gastric cancer.
Article
Oncology
Michele Sassano, Marco Mariani, Claudio Pelucchi, Martin Vicente, Marina Pinto-Carbo, Nuno Lunet, Samantha Morais, Carlo La Vecchia, Roberta Pastorino, Stefania Boccia
Summary: The study found that there is no clear association between chronic use of metformin and gastric cancer, indicating the need for further research.
CANCER EPIDEMIOLOGY
(2022)
Review
Food Science & Technology
Giovanna Muscogiuri, Luigi Barrea, Federica Campolo, Emilia Sbardella, Concetta Sciammarella, Maria Grazia Tarsitano, Filomena Bottiglieri, Annamaria Colao, Antongiulio Faggiano
Summary: Neuroendocrine neoplasms (NENs) are a heterogeneous group of neoplasms, and nutrition plays an important role in their management. Malnutrition negatively impacts on rates of complications, hospitalization, hospital stay, costs and mortality. Ketogenic diet (KD) is a promising approach as an adjuvant cancer therapy and can sensitize most cancers to standard treatment by exploiting the reprogramed metabolism of cancer cells.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Review
Nutrition & Dietetics
Emmanouil Bouras, Konstantinos K. Tsilidis, Marianthi Triggi, Antonios Siargkas, Michail Chourdakis, Anna-Bettina Haidich
Summary: In this Umbrella Review, the study provides an overview and evaluation of the associations of diet-related exposures with the risk of gastric cancer. The findings suggest that heavy alcohol consumption, salted fish consumption, high waist circumference, and unhealthy lifestyle choices are positively associated with gastric cancer, while maintaining a normal body weight and adopting a healthy lifestyle can reduce the risk. The quality of most meta-analyses included in the review is medium-to-high.
Article
Nutrition & Dietetics
Elena Boldo, Nerea Fernandez de Larrea, Marina Pollan, Vicente Martin, Mireia Obon-Santacana, Marcela Guevara, Gemma Castano-Vinyals, Jose Maria Canga, Beatriz Perez-Gomez, Ines Gomez-Acebo, Guillermo Fernandez-Tardon, Mercedes Vanaclocha-Espi, Rocio Olmedo-Requena, Juan Alguacil, Maria Dolores Chirlaque, Manolis Kogevinas, Nuria Aragones, Adela Castello
Summary: This study found that intake of red and processed meat increases the risk of gastric adenocarcinoma, especially for intestinal and non-cardia tumors. Individuals who prefer well done white or red meat have a higher risk of non-cardia and intestinal tumors compared to those who prefer rare/medium doneness. Stewing, griddling/barbequing, and oven baking are the cooking methods with the greatest effect on gastric adenocarcinoma.
Article
Medicine, General & Internal
James Webster, Darren C. Greenwood, Janet E. Cade
Summary: In the UK Women's Cohort Study, vegetarian women were found to have a higher risk of hip fracture compared to regular meat-eaters. Further research is recommended to confirm this finding in men and non-European populations and to explore the factors responsible for the observed risk difference.
Review
Oncology
Tiuri E. Kroese, Hanneke W. M. Van Laarhoven, Magnus Nilsson, Florian Lordick, Matthias Guckenberger, Jelle P. Ruurda, Domenico D'Ugo, Karin Haustermans, Eric Van Cutsem, Richard Van Hillegersberg, Peter S. N. Van Rossum
Summary: Local treatment may improve overall survival in patients with esophagogastric cancer and oligometastatic disease (OMD). The current literature defines OMD as the presence of metastases limited to one organ with no more than three lesions and the presence of an extra-regional lymph node station. Local treatment appears to be associated with improved OS compared to systemic therapy alone.
EUROPEAN JOURNAL OF CANCER
(2022)
Article
Oncology
Samantha Morais, Adriana Costa, Gabriela Albuquerque, Natalia Araujo, Claudio Pelucchi, Charles S. Rabkin, Linda M. Liao, Rashmi Sinha, Zuo-Feng Zhang, Jinfu Hu, Kenneth C. Johnson, Domenico Palli, Monica Ferraroni, Rossella Bonzi, Guo-Pei Yu, Lizbeth Lopez-Carrillo, Reza Malekzadeh, Shoichiro Tsugane, Akihisa Hidaka, Gerson Shigueaki Hamada, David Zaridze, Dmitry Maximovitch, Jesus Vioque, Manoli Garcia de la Hera, Victor Moreno, Mercedes Vanaclocha-Espi, Mary H. Ward, Mohammadreza Pakseresht, Raul Ulises Hernandez-Ramirez, Malaquias Lopez-Cervantes, Farhad Pourfarzi, Lina Mu, Robert C. Kurtz, Stefania Boccia, Roberta Pastorino, Areti Lagiou, Pagona Lagiou, Paolo Boffetta, M. Constanza Camargo, Maria Paula Curado, Eva Negri, Carlo La Vecchia, Nuno Lunet
Summary: Salty taste preference, always using table salt, and a greater intake of high-salt and salt-preserved foods are associated with an increased risk of gastric cancer. However, the association with total sodium intake was not significant. The results were consistent across various factors such as anatomic sites and Helicobacter pylori infection.
CANCER CAUSES & CONTROL
(2022)
Review
Food Science & Technology
Sara Moazzen, Kimberley J. W. van der Sloot, Geertruida H. de Bock, Behrooz Z. Alizadeh
Summary: The study found that high diet quality is associated with reduced risk of colorectal cancer, particularly with low Diet Inflammatory Index score and high Mediterranean Diet Score. However, concerns over inconsistency and imprecision led to the pooled results of all dietary indices being rated as low quality.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2021)
Article
Oncology
Hannah C. Puhr, Thorsten J. Reiter, Mohamed El-Mahrouk, Lena Saliternig, Peter Wolf, Maximilian J. Mair, Ariane Steindl, Matthias Paireder, Reza Asari, Sebastian F. Schoppmann, Anna S. Berghoff, Matthias Preusser, Ayseguel Ilhan-Mutlu
Summary: Thyroid hormones and their therapeutic interventions may be associated with the overall survival in patients with resectable gastroesophageal cancer. There is a tendency towards prolonged survival in hypothyroid patients and a significant positive correlation of thyroid hormone replacement therapy with the overall survival. The study suggests that thyroid disorders and their therapeutic interventions could serve as potential prognostic tools, warranting further prospective analyses.
Review
Nutrition & Dietetics
Lynsey N. Spillman, Angela M. Madden, Holly Richardson, Fumiaki Imamura, Danielle Jones, Marilyn Nash, Hong Kai Lim, Holly N. Hellawell, Kirsten L. Rennie, Linda Oude M. Griep, Michael Allison, Simon J. Griffin
Summary: Cardiovascular disease and its concurrent risk factors are common after liver transplant. Most of these risk factors can be improved through diet modification. This study aimed to review the literature on the nutritional intake of liver transplant recipients (LTR) and the factors influencing intake. The findings showed that LTR had a high-energy, low-quality diet with inadequate intake of fruits, vegetables, fiber, and adherence to cardiovascular disease prevention guidelines.
Review
Nutrition & Dietetics
Marta Correia, Ines Moreira, Sonia Cabral, Carolina Castro, Andreia Cruz, Bruno Magalhaes, Lucio Lara Santos, Susana Couto Irving
Summary: This systematic review identified three critical domains associated with nutritional status and clinical outcomes in gastric cancer patients undergoing neoadjuvant treatment. Body composition changes, particularly sarcopenia, were found to have a significant impact on treatment response and overall survival. However, the role of nutritional interventions during neoadjuvant chemotherapy has not been adequately explored.
Article
Oncology
Luca Giraldi, Jovana Stojanovic, Dario Arzani, Roberto Persiani, Jinfu Hu, Kenneth C. Johnson, Zuo-Feng Zhang, Monica Ferraroni, Domenico Palli, Guo-Pei Yu, Carlo La Vecchia, Claudio Pelucchi, Nuno Lunet, Ana Ferro, Reza Malekzadeh, Joshua Muscat, David Zaridze, Dmitry Maximovich, Nuria Aragones, Vicente Martin, Jesus Vioque, Eva M. Navarrete-Munoz, Mohammadreza Pakseresht, Eva Negri, Matteo Rota, Farhad Pourfarzi, Lina Mu, Robert C. Kurtz, Areti Lagiou, Pagona Lagiou, Roberta Pastorino, Stefania Boccia
Summary: This study aimed to examine the association between height and risk of gastric cancer. Through a large pooled analysis of case-control studies, the study found no significant association between adult height and gastric cancer.
EUROPEAN JOURNAL OF CANCER PREVENTION
(2023)
Review
Andrology
Sonia Cipriani, Elena Ricci, Francesca Chiaffarino, Giovanna Esposito, Michela Dalmartello, Carlo La Vecchia, Eva Negri, Fabio Parazzini
Summary: This study aims to evaluate the continuing trend of decreasing sperm count in Western European countries and USA. The results show no significant trends in sperm concentration in these regions.
Article
Oncology
M. Malvezzi, C. Santucci, P. Boffetta, G. Collatuzzo, F. Levi, C. La Vecchia, E. Negri
Summary: This study predicts cancer mortality figures for 2023 in the European Union, its five most populous countries, and the UK, with a focus on lung cancer. The results show that the decline in lung cancer mortality reflects advancements in tobacco control, and further efforts are needed to control overweight and obesity, alcohol consumption, infection, and related neoplasms, as well as improve screening, early diagnosis, and treatments. These efforts may achieve a 35% reduction in cancer mortality in the EU by 2035.
ANNALS OF ONCOLOGY
(2023)
Correction
Nutrition & Dietetics
Marta Rossi, Federica Turati, Panagiota Strikoudi, Monica Ferraroni, Maria Parpinel, Diego Serraino, Eva Negri, Carlo La Vecchia
BRITISH JOURNAL OF NUTRITION
(2023)
Article
Oncology
Harriet Rumgay, Marta Ortega-Ortega, Linda Sharp, Nuno Lunet, Isabelle Soerjomataram
Summary: More than 1.9 million people die from cancer each year in Europe. Alcohol use is a major modifiable risk factor for cancer and poses an economic burden on society. We estimated the cost of productivity lost due to premature death (under 65 years of age) from alcohol-attributable cancer in the European Union (EU) plus Iceland, Norway, Switzerland, and the United Kingdom (UK) in 2018.
CANCER EPIDEMIOLOGY
(2023)
Article
Nutrition & Dietetics
Michela Carola Speciani, Giorgio Gargari, Roberto Penagini, Massimiliano Mutignani, Monica Ferraroni, Arianna Natale, Michail Katsoulis, Marcello Cintolo, Pierfrancesco Leone, Aldo Airoldi, Maurizio Vecchi, Rossella Bonzi, Clorinda Ciafardini, Barbara Oreggia, Pietro Carnevali, Simone Guglielmetti, Patrizia Riso, Carlo La Vecchia, Marta Rossi
Summary: Garlic consumption is inversely associated with the risk of intestinal adenoma and colorectal cancer. This study found that medium/high garlic consumption is related to a decrease in the risk of colorectal cancer and is associated with changes in specific blood bacterial taxa.
EUROPEAN JOURNAL OF NUTRITION
(2023)
Article
Nutrition & Dietetics
Roberta De Vito, Federica Fiori, Monica Ferraroni, Silvia Cavalli, Roberto Caporali, Francesca Ingegnoli, Maria Parpinel, Valeria Edefonti
Summary: A recent Italian study found that higher consumption of olive oil and nuts may have a positive effect on disease activity in rheumatoid arthritis (RA), especially for patients with more severe or long-standing forms of the disease. Increasing intake of olive oil, olives, and nuts may be beneficial for improving disease activity in RA.
Article
Nutrition & Dietetics
Giulia Collatuzzo, Eva Negri, Claudio Pelucchi, Rossella Bonzi, Federica Turati, Charles S. Rabkin, Linda M. Liao, Rashmi Sinha, Domenico Palli, Monica Ferraroni, Lizbeth Lopez-Carrillo, Nuno Lunet, Samantha Morais, Demetrius Albanes, Stephanie J. Weinstein, Dominick Parisi, David Zaridze, Dmitry Maximovitch, Trinidad Dierssen-Sotos, Jose Juan Jimenez-Moleon, Jesus Vioque, Manoli Garcia de la Hera, Maria Paula Curado, Emmanuel Dias-Neto, Raul Ulises Hernandez-Ramirez, Malaquias Lopez-Cervantes, Mary H. Ward, Shoichiro Tsugane, Akihisa Hidaka, Areti Lagiou, Pagona Lagiou, Zuo-Feng Zhang, Antonia Trichopoulou, Anna Karakatsani, Maria Constanza Camargo, Carlo La Vecchia, Paolo Boffetta
Summary: A meta-analysis of 16 studies found no significant association between yoghurt consumption and gastric cancer risk.
Article
Oncology
Giulia Collatuzzo, Federica Turati, Matteo Malvezzi, Eva Negri, Carlo La Vecchia, Paolo Boffetta
Summary: This study estimated the number of cancers attributable to occupational carcinogens in Italy. By using a counterfactual scenario of no exposure and considering latency, the study calculated the attributable fraction of cancer. The most prevalent occupational carcinogens were found to be UV radiation, diesel exhaust, wood dust, and silica dust. The study highlighted the substantial burden of occupational cancers in Italy and the importance of surveillance of carcinogens in the workplace.
Article
Health Care Sciences & Services
Giovanna Esposito, Marta Rossi, Alessandro Favilli, Matteo Franchi, Giovanni Corrao, Fabio Parazzini, Carlo La Vecchia
Summary: We examined the impact of lockdown measures in Lombardy on obstetric and perinatal outcomes. Using healthcare databases, we compared births during the two lockdowns with births from corresponding periods in previous years. The proportion of low birth weight and preterm births decreased during the lockdowns, while induction of labor increased. There was no difference in stillbirth rate, but cesarean section was less frequent during the second lockdown.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Review
Obstetrics & Gynecology
Michela Dalmartello, Francesca Chiaffarino, Giovanna Esposito, Sonia Cipriani, Elena Ricci, Carlo La Vecchia, Fabio Parazzini, Luca Persani, Eva Negri
Summary: This review found that high maternal weight, primiparity, and early weight gain were associated with an increased risk of early breast onset/development, while preterm birth was associated with late breast onset/development. Results were inconsistent for smoking in pregnancy, maternal hypertensive disorders, breastfeeding, diabetes, and small for gestational age. No association was found for maternal age at delivery, alcohol drinking, and selected drug use during pregnancy, and low birth weight. This highlights the importance of studying the interconnections between pre/postnatal environmental exposures and their impact on puberty.
EARLY HUMAN DEVELOPMENT
(2023)
Article
Public, Environmental & Occupational Health
Margherita Pizzato, Matteo di Maso, Giulia Collatuzzo, Claudio Pelucchi, Federica Turati, Eva Negri, Carlo La Vecchia, Paolo Boffetta, Gianfranco Alicandro
Summary: This study quantifies the impact of educational inequalities on cancer mortality in Italy using data from the Italian 2011 census cohort. The results show that a substantial number of cancer deaths in Italy can be attributed to low levels of education, especially in men.
JOURNAL OF PUBLIC HEALTH
(2023)
Article
Cell Biology
Patricia Castro-Santos, Augusto Rojas-Martinez, Jose A. Riancho, Pablo Lapunzina, Carlos Flores, Angel Carracedo, Roberto Diaz-Pena, Scourge Cohort Group
Summary: We investigated the relationship between HLA polymorphisms and susceptibility to SARS-CoV-2 infection and disease severity. Genotyping data from 9373 COVID-19-positive cases and 5943 population controls were analyzed. The study found associations between HLA-B*14:02 and HLA-C*08:02 alleles with a lower risk of COVID-19 infection, and HLA-A*11:01 and HLA-C*04:01 alleles with disease severity.
Article
Oncology
Minkyo Song, Harindra Jayasekara, Claudio Pelucchi, Charles S. Rabkin, Kenneth C. Johnson, Jinfu Hu, Domenico Palli, Monica Ferraroni, Linda M. Liao, Rossella Bonzi, David Zaridze, Dmitry Maximovitch, Nuria Aragones, Vicente Martin, Gemma Castano-Vinyals, Marcela Guevara, Shoichiro Tsugane, Gerson Shigueaki Hamada, Akihisa Hidaka, Eva Negri, Mary H. Ward, Rashmi Sinha, Areti Lagiou, Pagona Lagiou, Paolo Boffetta, Maria Paula Curado, Nuno Lunet, Jesus Vioque, Zuo-Feng Zhang, Carlo La Vecchia, M. Constanza Camargo
Summary: This study aims to investigate and quantify the relationship between reproductive factors, menopausal hormone therapy (MHT), and gastric cancer risk in women. The results suggest a lower risk of gastric cancer in women with a longer duration of fertility and those who have used MHT after menopause.
CANCER CAUSES & CONTROL
(2023)
