Article
Chemistry, Applied
Qiming Wang, Yuwan Tang, Yaxuan Yang, Lin Lei, Xiaojuan Lei, Jichun Zhao, Yuhao Zhang, Lin Li, Qiang Wang, Jian Ming
Summary: The study found that CaCl2 concentration affects the morphology and structure of zein/FA complex, forming rough-surfaced spherical particles at 0.5mol/L concentration. Fourier transform infrared analysis showed changes in composition content, while molecular dynamics simulation revealed that FA interacts with zein mainly through hydrogen bonds and hydrophobic force.
Article
Chemistry, Applied
Qiming Wang, Yuwan Tang, Yaxuan Yang, Lin Lei, Xiaojuan Lei, Jichun Zhao, Yuhao Zhang, Lin Li, Qiang Wang, Jian Ming
Summary: This study investigates the interaction between ferulic acid (FA) and zein under different pH conditions, and reveals that pH alteration can affect the binding affinity of zein to FA, resulting in structural changes and increased antioxidant activity of zein. The study provides valuable insights for future research on food proteins stability and bioavailability of nutriceuticals.
FOOD HYDROCOLLOIDS
(2022)
Article
Materials Science, Biomaterials
Medha Surendranath, Rekha M. Ramesan, Prakash Nair, Ramesh Parameswaran
Summary: Thiolated polymers, specifically thiolated zein protein, demonstrated potential for mucoadhesive drug delivery. Through thiolation and purification optimization, a thiolated zein/polyethylene oxide (PEO) blend was developed and electrospun into fibrous matrices. The thiol modification improved the mechanical properties and adhesion in the rabbit intestinal mucosa. Non-cytotoxicity of the fabricated matrices with and without drug was confirmed through various in vitro cytotoxicity evaluations. Drug release studies showed that the thiolated zein/PEO matrix followed the Korsmeyer Peppas model of release, and permeation studies demonstrated its competence for transmucosal drug delivery.
JOURNAL OF MATERIALS CHEMISTRY B
(2023)
Article
Food Science & Technology
Negin Hashemi, Martin Kroyer Rasmussen, Emmanouil D. Tsochatzis, Milena Corredig
Summary: This study investigates the digestion and absorption process of curcumin in the gastrointestinal tract using in vitro models. The results show that curcumin loaded in zein nanoparticles can improve its bioavailability, and zein nanoparticles with sodium caseinate have inhibitory effects on cell proliferation.
JOURNAL OF FUNCTIONAL FOODS
(2023)
Article
Pharmacology & Pharmacy
Telma A. Jacinto, Breno Oliveira, Sonia P. Miguel, Maximiano P. Ribeiro, Paula Coutinho
Summary: This study utilized flash nanoprecipitation technique to produce zein and hyaluronic acid nanoparticles loaded with ciprofloxacin, and evaluated their potential for ocular drug delivery. The results showed that ZeinCPX_HA NPs had suitable particle size and polydispersity index, and maintained stability through the freeze-drying and resuspension process. Moreover, the nanoparticles exhibited good biocompatibility and sustained release of ciprofloxacin.
Article
Biochemistry & Molecular Biology
Zhiming Gao, Gaiting Chen, Wei Lu, Yuehan Wu, Bing Hu, Longquan Xu, Yapeng Fang, Katsuyoshi Nishinari, Glyn O. Phillips
Summary: This research compared the main zein fractions and found differences in their formation, surface adsorption, and emulsifying properties of anti-solvent-induced particles. The gamma-zein fraction displayed superior interfacial properties and emulsifying capabilities, making it a potential new application strategy for zein.
Article
Medicine, Research & Experimental
Parichehr Hassanzadeh, Elham Arbabi, Fatemeh Rostami
Summary: Nanotechnology-based approaches are utilized to enhance the pharmacological properties of the phenolic compound ferulic acid, demonstrating therapeutic potential in acute pancreatitis by targeted delivery.
Article
Agriculture, Dairy & Animal Science
Xiaoling Chen, Youxia Wang, Daiwen Chen, Bing Yu, Zhiqing Huang
Summary: The study found that dietary supplementation of 0.05% and 0.45% ferulic acid significantly increased intestinal antioxidant capacity and intestinal barrier function in weaned piglets.
ANIMAL BIOTECHNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Hye-Jeong Hwang, So Rok Lee, Ju-Gyeong Yoon, Hye-Ri Moon, Jingnan Zhang, Eunmi Park, Su-In Yoon, Jin Ah Cho
Summary: The intestinal epithelial barrier is crucial for defense against toxins and bacteria. Ferulic acid has anti-inflammatory properties and protects intestinal tight junctions.
Article
Chemistry, Applied
Teng Song, Zhiyu Xiong, Tong Shi, Li Yuan, Ruichang Gao
Summary: The study found that glutamic acid and zein combined in the form of noncovalent bonds, altering the characteristics of zein. Glutamic acid induced colloidal particle aggregation, altering the distribution of droplets in the emulsion and increasing protein adsorption on oil droplet surfaces. Hydrophobic and electrostatic interactions were the main driving forces for colloidal particle formation, as determined by force analysis and zeta potential changes.
Article
Agriculture, Dairy & Animal Science
Xiaoyu Yin, Wuyun Liu, Hao Chen, Chelimuge Qi, Hongsong Chen, Huaxin Niu, Jingfeng Yang, Kevin W. H. Kwok, Wu Dong
Summary: Ferulic acid (FA) is a common ingredient in Chinese herbal medicine that has been found to promote growth and improve meat quality in animals, particularly in the skeletal muscles. It enhances feed assimilation, increases muscle fiber width, and regulates gut cell and microbiota composition. The gene expression changes induced by FA are beneficial for fatty acid metabolism and reduction of fat deposition.
JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION
(2022)
Article
Food Science & Technology
Xiao Liang, Kaixin Cao, Wan Li, Xiaoqiang Li, David Julian McClements, Kun Hu
Summary: This research successfully loaded tannic acid into zein nanoparticles and coated them with anionic pectin, forming core-shell nanoparticles. The nanoparticles showed resistance to flocculation under various conditions, preserved the antioxidant capacity of tannic acid, and released the compound primarily in the small intestine. These findings suggest that pectin-coated zein nanoparticles could be effective encapsulation and delivery systems for hydrophilic polyphenols.
FOOD RESEARCH INTERNATIONAL
(2021)
Article
Agricultural Engineering
Jing-Jing Zhu, Xiao-Nan Huang, Tao Yang, Chuan-He Tang, Shou-Wei Yin, Xiao-Jiang Jia, Xiao-Quan Yang
Summary: In this study, zein-based topical vehicles were constructed for the first time to address skin photoaging. The nanoparticles co-assembled zein with hyaluronic acid to encapsulate hydrophobic tetra-hydrocurcumin (THC), significantly improving its solubility in water. The topical delivery systems showed effectiveness in UVB-induced cell and animal photoaging models and had the potential to develop innovative nanocosmetics containing anti-photoaging ingredient.
INDUSTRIAL CROPS AND PRODUCTS
(2022)
Article
Pharmacology & Pharmacy
Yan Qi, Wenzhao Liu, Xuefang Yan, Chen Zhang, Chunmei Zhang, Lingxin Liu, Xuehui Zheng, Mengying Suo, Yun Ti, Mei Ni, Meng Zhang, Peili Bu
Summary: In this study, we investigated the effects of Tongxinluo on atherosclerosis in rabbits and found that it improved plaque stability, reduced inflammation, and modulated gut microbiota and metabolism. These findings suggest that Tongxinluo may have potential therapeutic benefits in treating atherosclerosis.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Qi Zhang, Dong Li, Shuang Guan, Dan Liu, Jing Wang, Guihua Xing, Liling Yue, Defu Cai
Summary: Polysialic acid (PSA) modified zein nanoparticles were developed for targeted delivery of honokiol (HNK) to enhance drug delivery efficiency and specific biodistribution at tumor sites. Animal experiments confirmed the favorable antitumor efficacy and biosafety of PSA-Zein-HNK, suggesting its potential as an efficient tumor-targeted drug delivery strategy for breast cancer treatment.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Review
Pharmacology & Pharmacy
Catarina Pacheco, Ana Baiao, Tao Ding, Wenguo Cui, Bruno Sarmento
Summary: The systemic use of chemotherapy for cancer treatment is limited by its toxicity. Drug delivery systems (DDSs) have been designed to avoid systemic toxicity by protecting drugs and controlling drug release. However, the approval of tailored DDSs for clinical use is minimal due to the need for improvement in safety and in vivo activity.
ADVANCED DRUG DELIVERY REVIEWS
(2023)
Article
Instruments & Instrumentation
Fatima Hameedat, Soraia Pinto, Joana Marques, Sofia Dias, Bruno Sarmento
Summary: Peptides have great potential for treating chronic conditions and there are more than 80 peptides available in the global market. However, most of the marketed peptide drugs are administered intravenously or subcutaneously due to their fast degradation and limited absorption through non-invasive routes. In this study, candidate protein delivery systems for pulmonary administration of peptides were developed and characterized. The targeted PEGylated zein nanoparticles (ZNPs) showed promising results in enhancing insulin permeability and are suitable as peptide carriers for pulmonary delivery.
DRUG DELIVERY AND TRANSLATIONAL RESEARCH
(2023)
Article
Instruments & Instrumentation
Paulo Faria, Catarina Pacheco, Rui Pedro Moura, Bruno Sarmento, Claudia Martins
Summary: Brain diseases pose a significant social and economic burden, and their complexity makes single-drug therapies insufficient. Nanomedicine, with its ability to target the brain and deliver multiple cargos, shows promise in overcoming therapeutic resistance. This review explores the mechanisms of therapeutic resistance in brain diseases, the use of multifunctional nanomedicines to tackle multiple aspects of the disease microenvironment, and the promising therapeutic responses achieved by cutting-edge multifunctional nanomedicines.
DRUG DELIVERY AND TRANSLATIONAL RESEARCH
(2023)
Review
Pharmacology & Pharmacy
Lais de Almeida Campos, Margani Taise Fin, Kelvin Sousa Santos, Marcos William de Lima Gualque, Ana Karla Lima Freire Cabral, Najeh Maissar Khalil, Ana Marisa Fusco-Almeida, Rubiana Mara Mainardes, Maria Jose Soares Mendes-Giannini
Summary: Invasive fungal infections have become a significant cause of mortality and morbidity worldwide. The current treatment options are limited due to low bioavailability and toxicity. Voriconazole is widely used to treat various fungal infections, but its non-linear pharmacokinetics and individual variations in metabolism can lead to supratherapeutic doses and increased toxicity. Recent research has explored the use of nanotechnology-based drug delivery systems to improve the delivery of voriconazole. These systems have shown promising results in enhancing drug permeation and deposition in target tissues, allowing for controlled and sustained release in different administration routes. Overall, nanotechnology-based drug delivery systems offer a more effective and safer alternative for treating fungal infections.
Article
Pharmacology & Pharmacy
Suzana Carvalho, Maria Jose Silveira, Mariana Domingues, Barbara Ferreira, Catarina Leite Pereira, Maria Palmira Gremiao, Bruno Sarmento
Summary: This study proposes a multicellular spheroid model of colorectal cancer (CRC) for screening the antiangiogenic potential of novel nanomedicines. The developed model consists of HCT116 cells, human pulmonary microvascular endothelial cell (HPMEC), fibroblasts, and macrophages. It exhibits intrinsic CRC features and shows that Gellan gum/chitosan nanoparticles encapsulating BVZ have superior antiangiogenic properties compared to free BVZ.
ADVANCED THERAPEUTICS
(2023)
Article
Nanoscience & Nanotechnology
Amir Soleimany, Sepideh Khoee, Sofia Dias, Bruno Sarmento
Summary: In this study, a new nanohybrid consisting of thiolated chitosan-coated gold nanostars (AuNS-TCS) as the photothermal agent and riboflavin-conjugated N,S-doped graphene quantum dot (Rf-N,S-GQD) as the two-photon photosensitizer (TP-PS) was developed. The nanohybrid exhibited combined TP-PDT/PTT when a low-power, single-pulsed laser irradiation was applied. The study demonstrates a successful single-laser-triggered, synergistic combined TP-PDT/PTT based on a plasmonic metal/QD hybrid, with potential for future investigation in clinical settings.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Applied
Diana Pinto, Andreia Almeida, Anallely Lopez-Yerena, Soraia Pinto, Bruno Sarmento, Rosa Lamuela-Raventos, Anna Vallverdu-Queralt, Cristina Delerue-Matos, Francisca Rodrigues
Summary: This study demonstrates the in-vivo antioxidant properties of chestnut shell extract, as well as its protective effects against hemolysis and elevated blood glucose and lipids levels. Additionally, the study provides new insights on the metabolomic profiling of polyphenols.
Review
Environmental Sciences
Maria Joao Bessa, Bruno Sarmento, Marta Oliveira, Francisca Rodrigues
Summary: Firefighters are exposed to health-relevant pollutants released during fires, and in vitro studies using human cell models have shown decreased viability, increased oxidative stress, elevated pro-inflammatory cytokines levels, and increased cell death frequencies. However, more research is needed to understand the toxicity mechanisms initiated by firefighting activities and establish occupational exposure limits for firefighters.
JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS
(2023)
Article
Instruments & Instrumentation
Priscila Zimath, Soraia Pinto, Sofia Dias, Alex Rafacho, Bruno Sarmento
Summary: This study loaded MF into zein NPs and evaluated the potential advantages of oral delivery and the application in treating intestinal inflammatory diseases.
DRUG DELIVERY AND TRANSLATIONAL RESEARCH
(2023)
Review
Pharmacology & Pharmacy
Diana Rafael, Marcelo Guerrero, Adolfo Marican, Diego Arango, Bruno Sarmento, Roser Ferrer, Esteban F. Duran-Lara, Simon J. Clark, Simo Schwartz
Summary: Slow-release delivery systems are crucial for long-term sustained treatments of retinal diseases. Hydrogels, especially temperature-responsive hydrogels, have been studied as promising delivery vehicles for intravitreal injection of retinal therapies.
Article
Engineering, Biomedical
Francisca Diniz, Sofia Lamas, Hugo Osorio, Paulo Aguiar, Daniela Freitas, Fatima Gartner, Bruno Sarmento, Celso A. Reis, Joana Gomes
Summary: This study demonstrates the potential of using nanoparticles targeting STn for delivering FRT as a therapeutic approach in gastric cancer. The nanoparticles effectively reduced tumor growth, cell proliferation, and tumor necrosis in vivo.
ACTA BIOMATERIALIA
(2023)
Article
Engineering, Biomedical
Qimanguli Saiding, Yiyao Chen, Juan Wang, Catarina Leite Pereira, Bruno Sarmento, Wenguo Cui, Xinliang Chen
Summary: Hernia reconstruction is a frequently performed surgical procedure that has been greatly improved by plastic surgery techniques. Surgical meshes are commonly used for abdominal wall hernia repair, but there are still challenges in mesh design and complications. This review provides a comprehensive summary of hernia surgical mesh development, including commercial meshes, prosthetic materials, and engineered prosthetics. The review also outlines future research directions for successful hernia repair solutions.
MATERIALS TODAY BIO
(2023)
Article
Chemistry, Medicinal
Cecilia Cristelo, Rute Nunes, Soraia Pinto, Joana Moreira Marques, Francisco Miguel Gama, Bruno Sarmento
Summary: This study successfully loaded the LLKKK18 peptide onto PLGA nanoparticles and demonstrated the targeted delivery to beta cells, as well as the promotion of insulin release and increase in beta cell mass. This research provides insights for new therapeutic approaches in T1D treatment.
ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE
(2023)
Review
Pharmacology & Pharmacy
Andrea Cunha, Patricia M. A. Silva, Bruno Sarmento, Odilia Queiros
Summary: The Warburg effect is a metabolic shift that leads to acidification of the tumor microenvironment and increased drug resistance. The metabolic differences between cancer and normal cells provide a strategy for new therapies, and nanodrug delivery systems can overcome multidrug resistance.
Review
Chemistry, Multidisciplinary
Ana Margarida Carvalho, Ruchi Bansal, Cristina C. Barrias, Bruno Sarmento
Summary: Biomaterials are crucial for creating in vitro models of human liver fibrosis, as they allow for a more accurate replication of cell-matrix interactions. These models can provide insights into the development and treatment of liver disease.
ADVANCED MATERIALS
(2023)
Article
Biochemistry & Molecular Biology
Wei-Han Hui, Yen-Lin Chen, Shu-Wei Chang
Summary: Crosslinking affects the mechanical behavior and tissue metabolism of collagen-based tissues. Aging and diabetes alter the crosslinking type and density, thus changing tissue properties. High-connectivity enzymatic crosslinking and advanced-glycation end-products result in uniform deformation under daily activity, while low-connectivity enzymatic crosslinking does not. High-connectivity model displays more sliding, while AGEs induce instability in structures near the binding sites.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yao-Bin Ma, Xiao-Qiu Zhou, Wei-Dan Jiang, Pei Wu, Yang Liu, Shu-Wei Li, Ling Tang, Lu Zhang, Hai-Feng Mi, Lin Feng
Summary: Tea polyphenols (TPs) are an inexpensive feed additive that can protect the gill function of fish against Flavobacterium columnare (F. columnare) through various mechanisms, including suppression of oxidative stress, apoptosis, and inflammation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yan-Jia Guo, Jing-Ru Pang, Yu Zhang, Zhong-Rui Li, Xiao-Lin Zi, Hong-Min Liu, Ning Wang, Li-Juan Zhao, Ya Gao, Bo Wang, Piet Herdewijn, Cheng-Yun Jin, Ying Liu, Yi-Chao Zheng
Summary: This study identifies the conjugation of NEDD8 to LSD1 and its impact on GC cells, revealing the significance of LSD1 neddylation in GC.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Geum-Jae Jeong, Fazlurrahman Khan, Nazia Tabassum, Young-Mog Kim
Summary: Vibrio species are motile gram-negative bacteria commonly found in aquatic environments. They can adapt to environmental fluctuations and develop protective mechanisms against host immune systems. Different types of sigma and anti-sigma factors play important roles in regulating gene expression and virulence in Vibrio species.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Zahra Mohammadbagheri, Behrooz Movahedi, Shaghayegh Saeedi, Abbas Rahmati
Summary: In this study, a reusable biobased composite hydrogel was successfully synthesized and used for the removal of Tl(I) from aqueous solutions. The hydrogel exhibited high adsorption capacity and thermal stability, and the adsorption process was found to be thermodynamically spontaneous. The results demonstrated that the hydrogel can be reused multiple times without significant loss of its adsorption capacity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Iqra Batool, Muhammad Imran, Ayesha Anwar, Farhan Ahmed Khan, Afrah E. Mohammed, Ashwag Shami, Hafiz Iqbal
Summary: Enzyme immobilization on ZnO/SnO2 and ZnO/SnO2/SA nanocomposites was studied, and the catalytic and biochemical characteristics of the immobilized enzyme were investigated. The results showed that ZnO/SnO2 and ZnO/SnO2/SA nanostructures are suitable carriers for enzyme immobilization.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Elias Mosaffa, Dhruvi Patel, Nasim Amiri Ramsheh, Rishikumar Indravadan Patel, Atanu Banerjee, Hossein Ghafuri
Summary: In this study, a unique 3D bead structure of adsorbent, composed of bacterial cellulose microfilaments reinforced chitosan adorned with melamine 2D plates, was synthesized for anionic dye removal. The adsorbent showed high specific surface area and abundant functional groups, resulting in exceptional adsorption capacity. The characteristics and optimal conditions of the adsorbent were assessed and analyzed.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Carolina Gismene, Jorge Enrique Hernandez Gonzalez, Marilia de Freitas Calmon, Andrey Fabricio Ziem Nascimento, Angela Rocio Nino Santisteban, Felipe Antunes Calil, Alana Della Torre da Silva, Paula Rahal, Rejane Maira Goes, Raghuvir Krishnaswamy Arni, Ricardo Barros Mariutti
Summary: Mammaliicoccus sciuri, a bacterium of clinical and veterinary relevance, expresses the virulence factor Exfoliative Toxin C (ExhC), which binds specifically to desmoglein-1 (Dsg1) and plays a role in tissue integrity. This study investigates the necrotic activity of ExhC and identifies a variant lacking necrotic potential but retaining enzymatic activity through mutagenesis experiments and crystal structure determination.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Bibhas K. Bhunia, Ashutosh Bandyopadhyay, Souradeep Dey, Biman B. Mandal
Summary: Intervertebral disc degeneration is a major cause of chronic low back pain and disability. Researchers have developed a bioactive silk-based hybrid hydrogel system functionalized with decellularized human Wharton's jelly extracellular matrix as bioactive cues. The hydrogels mimic the rheological and mechanical properties of the native nucleus pulposus tissue and support cell viability, proliferation, and tissue maturation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Qun Zhang, Yonggan Yan, Zhao Li, Jing Du, Kai Zhang, Liguo Zhang, Ting Wang, Alberto Bianco, Shaohua Ge, Baojin Ma
Summary: A new crosslinking strategy has been devised to construct injectable sodium alginate hydrogels, which can be regulated for injectability and have great potential in biomedical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Seong Eun Hong, Ji-Soo Lee, Hyeon Gyu Lee
Summary: The potential of multi-layer nanoemulsions for improving the cellular uptake, antioxidant activity, and in vitro bioaccessibility of alpha-tocopherol was examined. The results showed that the multi-layer nanoemulsions significantly enhanced the cellular uptake and antioxidant activity of alpha-tocopherol compared to free coumarin 6. Furthermore, the use of chitosan and dextran sulfate as wall materials in the multi-layer nanoemulsions led to even higher cellular uptake, in vitro bioaccessibility, and antioxidant activity of alpha-tocopherol.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jingjing Yu, Yanhui Zhang, Ruoning Zhang, Yanxiang Gao, Like Mao
Summary: High internal phase emulsions (HIPEs) based on beeswax (BW) oleogels and octenyl succinic acid starch (OSA starch) were prepared by a simple one-step method. The results showed that oleogelation improved the stability and encapsulation capability of the HIPEs, which is significant for the development of novel healthy food.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Bi-Feng Yao, Xiu-Ju Luo, Jun Peng
Summary: The balanced and continuous fission and fusion of mitochondria, regulated by OPA1, are important for maintaining mitochondrial dynamics in cardiovascular disorders. Understanding the role of OPA1 in mitochondrial fusion can provide insights into the pathogenesis of cardiovascular diseases.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Gokul Paramasivam, Anandhavelu Sanmugam, Vishnu Vardhan Palem, Murugan Sevanan, Ananda Babu Sairam, Nachiappan Nachiappan, Buhyun Youn, Jung Sub Lee, Muthuchamy Nallal, Kang Hyun Park
Summary: Nanomaterials are being used to deliver therapeutic agents in living systems. Different nanotechnological applications such as immunosensors, immune assays, and drug delivery are being implemented using nanotechnology. Genomics plays a crucial role in selecting appropriate drugs for personalized cancer therapy. It helps in analyzing gene and protein expression, disease classification, and designing disease models. Delivering drugs to specific areas using nanoparticles is a challenging issue.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jing Li, Wei Wang, Han Wu, Feng Peng, Hui Gao, Ying Guan
Summary: In this study, CMH-based CPF films were prepared and their thermal and barrier properties were successfully regulated. The tensile strength and water vapor barrier property of CPF films were significantly improved, making them promising for food packaging applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)