Hydrophobic interactions between polymeric carrier and palmitic acid-conjugated siRNA improve PEGylated polyplex stability and enhance in vivo pharmacokinetics and tumor gene silencing

Title
Hydrophobic interactions between polymeric carrier and palmitic acid-conjugated siRNA improve PEGylated polyplex stability and enhance in vivo pharmacokinetics and tumor gene silencing
Authors
Keywords
RNA interference, PEGylated polyplexes, Pharmacokinetics, Hydrophobicity, Breast cancer, Tumor targeting
Journal
BIOMATERIALS
Volume 97, Issue -, Pages 122-132
Publisher
Elsevier BV
Online
2016-04-29
DOI
10.1016/j.biomaterials.2016.04.017

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