The role of Müller cell glucocorticoid signaling in diabetic retinopathy

The agonistic TSPO ligand XBD173 attenuates the glial response thereby protecting inner retinal neurons in a murine model of retinal ischemia

(2019) Kristin Mages et al.   Journal of Neuroinflammation

Molecular Classification and Comparative Taxonomics of Foveal and Peripheral Cells in Primate Retina

(2019) Yi-Rong Peng et al.   CELL

Gene Therapy Leaves a Vicious Cycle

(2019) Reena Goswami et al.   Frontiers in Oncology

Safety and Long-Term Efficacy of AAV4 Gene Therapy in Patients with RPE65 Leber Congenital Amaurosis

(2018) Guylène Le Meur et al.   MOLECULAR THERAPY

Glucocorticoid receptor signaling in the eye

(2018) Rania S. Sulaiman et al.   STEROIDS

TRPC proteins contribute to development of diabetic retinopathy and regulate glyoxalase 1 activity and methylglyoxal accumulation

(2018) Robin Sachdeva et al.   Molecular Metabolism

Gene therapy for diabetic retinopathy: Are we ready to make the leap from bench to bedside?

(2017) Jiang-Hui Wang et al.   PHARMACOLOGY & THERAPEUTICS

Hair corticosterone measurement in mouse models of type 1 and type 2 diabetes mellitus

(2017) Rebecca L. Erickson et al.   PHYSIOLOGY & BEHAVIOR

Müller cells and diabetic retinopathy

(2017) Brandon A. Coughlin et al.   VISION RESEARCH

Neurodegeneration and Neuroinflammation in Diabetic Retinopathy: Potential Approaches to Delay Neuronal Loss

(2016) Joanna Kad|ubowska et al.   Current Neuropharmacology

STAT3 signaling in immunity

(2016) Emily J. Hillmer et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Dicarbonyls and glyoxalase in disease mechanisms and clinical therapeutics

(2016) Naila Rabbani et al.   GLYCOCONJUGATE JOURNAL

Endothelial STAT3 Activation Increases Vascular Leakage Through Downregulating Tight Junction Proteins: Implications for Diabetic Retinopathy

(2016) Jang-Hyuk Yun et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Corticosteroids

(2016) Sivapriya Ramamoorthy et al.   RHEUMATIC DISEASE CLINICS OF NORTH AMERICA

TGF-β and the TGF-β Family: Context-Dependent Roles in Cell and Tissue Physiology

(2016) Masato Morikawa et al.   Cold Spring Harbor Perspectives in Biology

Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets

(2015) Evan Z. Macosko et al.   CELL

Activation of glucocorticoid receptors in Müller glia is protective to retinal neurons and suppresses microglial reactivity

(2015) Donika Gallina et al.   EXPERIMENTAL NEUROLOGY

Glucocorticoids: Structure, Signaling and Molecular Mechanisms in the Treatment of Diabetic Retinopathy and Diabetic Macular Edema

(2014) X. Zhang et al.   CURRENT MOLECULAR MEDICINE

Glucocorticoid receptors in the retina, Muller glia and the formation of Muller glia-derived progenitors

(2014) D. Gallina et al.   DEVELOPMENT

New treatments for diabetic retinopathy

(2014) A. Das et al.   DIABETES OBESITY & METABOLISM

Comprehensive Overview of the Structure and Regulation of the Glucocorticoid Receptor

(2014) Sofie Vandevyver et al.   ENDOCRINE REVIEWS

Müller glial cells inhibit proliferation of retinal endothelial cells via TGF-β2 and Smad signaling

(2014) Yousef Yafai et al.   GLIA

Effect of glucocorticoids on neuronal and vascular pathology in a transgenic model of selective Müller cell ablation

(2014) Weiyong Shen et al.   GLIA

Diabetic macular edema: new concepts in patho-physiology and treatment

(2014) Xinyuan Zhang et al.   Cell and Bioscience

Oxidative stress in angiogenesis and vascular disease

(2013) Y.-W. Kim et al.   BLOOD

New functions of Müller cells

(2013) Andreas Reichenbach et al.   GLIA

Mechanisms of Diabetic Complications

(2013) Josephine M. Forbes et al.   PHYSIOLOGICAL REVIEWS

Protective Effects of Adeno-associated Virus Mediated Brain-derived Neurotrophic Factor Expression on Retinal Ganglion Cells in Diabetic Rats

(2012) Yan Gong et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Global Prevalence and Major Risk Factors of Diabetic Retinopathy

(2012) J. W. Y. Yau et al.   DIABETES CARE

Update on animal models of diabetic retinopathy: from molecular approaches to mice and higher mammals

(2012) R. Robinson et al.   Disease Models & Mechanisms

Turning a blind eye to anti-VEGF toxicities

(2012) Susan E. Quaggin   JOURNAL OF CLINICAL INVESTIGATION

Conditional Muller Cell Ablation Causes Independent Neuronal and Vascular Pathologies in a Novel Transgenic Model

(2012) W. Shen et al.   JOURNAL OF NEUROSCIENCE

The Stat3/GR Interaction Code: Predictive Value of Direct/Indirect DNA Recruitment for Transcription Outcome

(2012) David Langlais et al.   MOLECULAR CELL

Long-Term Retinal PEDF Overexpression Prevents Neovascularization in a Murine Adult Model of Retinopathy

(2012) Virginia Haurigot et al.   PLoS One

Role of transcriptional coregulator GRIP1 in the anti-inflammatory actions of glucocorticoids

(2012) Y. Chinenov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AGEs, RAGE, and Diabetic Retinopathy

(2011) Hongliang Zong et al.   Current Diabetes Reports

Differential Roles of Hyperglycemia and Hypoinsulinemia in Diabetes Induced Retinal Cell Death: Evidence for Retinal Insulin Resistance

(2011) Patrice E. Fort et al.   PLoS One

Oxidative Stress and Diabetic Complications

(2010) Ferdinando Giacco et al.   CIRCULATION RESEARCH

Cortisol Exerts bi-phasic Regulation of Inflammation in Humans

(2010) Mark P. Yeager et al.   Dose-Response

Involvement of oxidative stress and mitochondrial dysfunction in the osmotic swelling of retinal glial cells from diabetic rats

(2010) Katja Krügel et al.   EXPERIMENTAL EYE RESEARCH

Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies

(2010) The Emerging Risk Factors Collaboration   LANCET

The role of vitamin E and oxidative stress in diabetes complications

(2010) Robert Pazdro et al.   MECHANISMS OF AGEING AND DEVELOPMENT

The Transforming Growth Factor-  Pathway Is a Common Target of Drugs That Prevent Experimental Diabetic Retinopathy

(2009) C. Gerhardinger et al.   DIABETES

Effect of Glycemic Exposure on the Risk of Microvascular Complications in the Diabetes Control and Complications Trial--Revisited

(2008) J. M. Lachin et al.   DIABETES

Purinergic receptor activation inhibits osmotic glial cell swelling in the diabetic rat retina

(2008) Antje Wurm et al.   EXPERIMENTAL EYE RESEARCH

Novel anti-VEGF chimeric molecules delivered by AAV vectors for inhibition of retinal neovascularization

(2008) P Pechan et al.   GENE THERAPY

Inhibition of retinal neovascularization by gene transfer of small interfering RNA targeting HIF-1α and VEGF

(2008) Jian Jiang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Effect of Gene Therapy on Visual Function in Leber's Congenital Amaurosis

(2008) James W.B. Bainbridge et al.   NEW ENGLAND JOURNAL OF MEDICINE

Oxidative stress and diabetic retinopathy: Pathophysiological mechanisms and treatment perspectives

(2008) Sally A. Madsen-Bouterse et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS