Review
Oncology
Ying Wu, Meilin Zhu, Yiming Liu, Xinyue Cao, Guojin Zhang, Longlin Yin
Summary: This study investigated the association between microvascular invasion (MVI) and the peritumoral imaging features of gadolinium ethoxybenzyl DTPA-enhanced magnetic resonance imaging (Gd-EOB-DTPA-enhanced MRI) in hepatocellular carcinoma (HCC). The results showed that the peritumoral imaging features had high specificity but low sensitivity in predicting hepatic MVI, indicating that it can be used as a noninvasive, excluded diagnosis.
FRONTIERS IN ONCOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yixing Yu, Yanfen Fan, Ximing Wang, Mo Zhu, Mengjie Hu, Cen Shi, Chunhong Hu
Summary: The study developed a Gd-EOB-DTPA-enhanced MRI radiomics model for preoperative prediction of VETC and patient prognosis in hepatocellular cancer (HCC). The peritumoral radiomics model showed higher AUC than intratumoral model and was an independent predictor of early recurrence and progression-free survival (PFS). The radiomics models may be useful in preoperatively predicting VETC and patient prognosis.
EUROPEAN RADIOLOGY
(2022)
Article
Oncology
Yanfen Fan, Yixing Yu, Ximing Wang, Mengjie Hu, Mingzhan Du, Lingchuan Guo, Shifang Sun, Chunhong Hu
Summary: This study utilized texture analysis based on GdEOB-DTPA-enhanced MRI to identify VETC-positive HCC, finding specific texture features that were significantly associated with VETC-positive HCC and could effectively differentiate this type of tumor.
JOURNAL OF HEPATOCELLULAR CARCINOMA
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Jie Cheng, Xiaofeng Li, Limei Wang, Fengxi Chen, Yiman Li, Guojiao Zuo, Mi Pei, Huarong Zhang, Linze Yu, Chen Liu, Jian Wang, Qi Han, Ping Cai, Xiaoming Li
Summary: This study compared the performance of Gd-EOB-DTPA MRI and CT in differentiating MTM-HCC from non-MTM-HCC. The results showed that Gd-EOB-DTPA MRI outperformed CT in both the training and external validation cohorts. A nomogram incorporating AFP, PT-INR, and MRI features demonstrated high diagnostic performance for MTM-HCC in the external validation cohort. Intratumor necrosis or ischemia was found to be an independent indicator for poor prognosis.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2023)
Article
Oncology
Ziwei Liu, Shaomin Yang, Xinjie Chen, Chun Luo, Jieying Feng, Haixiong Chen, Fusheng Ouyang, Rong Zhang, Xiaohong Li, Wei Liu, Baoliang Guo, Qiugen Hu
Summary: T1rt-Pre and T1rt-20min showed strong positive correlation with Ki-67 expression in HCC, and the nomogram based on Gd-EOB-DTPA enhanced MRI combined with T1 mapping effectively predicted high Ki-67 expression in HCC with good concordance indices in the training and validation cohorts.
FRONTIERS IN ONCOLOGY
(2022)
Review
Radiology, Nuclear Medicine & Medical Imaging
Tae-Hyung Kim, Sungmin Woo, Sangwon Han, Chong Hyun Suh, Richard Kinh Gian Do, Jeong Min Lee
Summary: This systematic review and meta-analysis aimed to identify the risk factors for hypervascularization in hepatocellular carcinoma patients with hepatobiliary phase hypointense nodules without arterial phase hyperenhancement. The results showed that nodules with baseline size greater than 10 mm, T2 hyperintensity, restricted diffusion, and previous history of hepatocellular carcinoma had a higher risk of hypervascularization.
ACADEMIC RADIOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Zhaoqi Shi, Wenli Cai, Xu Feng, Jingwei Cai, Yuelong Liang, Junjie Xu, Junhao Zhen, Xiao Liang
Summary: This study aimed to evaluate the effectiveness of radiomics analysis based on Gd-EOB-DTPA enhanced hepatic MRI for functional liver reserve assessment in HCC patients. The results showed that radiomics analysis can be used to assess functional liver reserve and effectively identify patients with ICG R15<10%.
ACADEMIC RADIOLOGY
(2022)
Article
Gastroenterology & Hepatology
Han-Dan Zhang, Xiao-Ming Li, Yu-Han Zhang, Fang Hu, Liang Tan, Fang Wang, Yang Jing, Da-Jing Guo, Yang Xu, Xian-Ling Hu, Chen Liu, Jian Wang
Summary: This study established and compared the efficacy of the clinicoradiological model, radiomics model, and clinicoradiological-radiomics hybrid model in predicting the microvascular invasion of hepatocellular carcinoma using Gd-EOB-DTPA enhanced MRI. The results showed that the hybrid model provided the best prediction results.
JOURNAL OF CLINICAL AND TRANSLATIONAL HEPATOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yanfen Fan, Yixing Yu, Ximing Wang, Mengjie Hu, Chunhong Hu
Summary: This study investigated the use of radiomics models derived from enhanced MRI images to predict Ki-67 expression in hepatocellular carcinoma. The arterial phase radiomics model showed better predictive performance, with the combined model including AP Rad-score and serum AFP levels improving the predictive accuracy further. The findings suggest that a combined model based on enhanced MRI can accurately predict Ki-67 expression in HCC preoperatively.
BMC MEDICAL IMAGING
(2021)
Article
Oncology
Wolf Baeumler, Philipp Wiggermann, Lukas Luerken, Marco Dollinger, Christian Stroszczynski, Lukas P. Beyer, Andreas Schicho
Summary: The study investigated local tumor progression after IRE treatment of HCC and found MR imaging features helpful in identifying re-grown viable tumors. LTP was mainly detected in the peripheral ablation zone, with T2 BLADE and diffusion sequences aiding detection in the peripheral zone, while T1 p.v. and T1 d.p. showed the highest sensitivity in the central zone.
Review
Radiology, Nuclear Medicine & Medical Imaging
Tae-Hyung Kim, Jeong Min Lee, Dong Ho Lee, Ijin Joo, Sae-Jin Park, Jung Hee Yoon
Summary: This study compared the local tumor progression (LTP) of percutaneous no-touch radiofrequency ablation (NtRFA) with conventional radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC) <= 5 cm through a systematic review and meta-analysis. The results showed that NtRFA had a lower LTP rate of 6% compared to conventional RFA.
EUROPEAN RADIOLOGY
(2023)
Article
Oncology
Chengming Qu, Qiang Wang, Changfeng Li, Qiao Xie, Ping Cai, Xiaochu Yan, Ernesto Sparrelid, Leida Zhang, Kuansheng Ma, Torkel B. Brismar
Summary: The aim of this study is to establish and validate a radiomics-based model using preoperative Gd-EOB-DTPA-enhanced MRI to predict microvascular invasion (MVI) in patients with hepatocellular carcinoma <= 5 cm.
FRONTIERS IN ONCOLOGY
(2022)
Review
Oncology
Tian-Run Lv, Hai-Jie Hu, Parbatraj Regmi, Fei Liu, Fu-Yu Li
Summary: Sarcomatoid hepatocellular carcinoma (SHCC) is a rare subtype of primary liver malignancies. Compared to conventional hepatocellular carcinoma (HCC), SHCC has worse prognosis and exhibits more aggressive behavior.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
(2022)
Review
Oncology
Berend R. Beumer, Stefan Buettner, Boris Galjart, Jeroen L. A. van Vugt, Robert A. de Man, Jan N. M. IJzermans, Bas Groot Koerkamp
Summary: This study evaluated prognostic models for Hepatocellular Carcinoma (HCC) and set a benchmark for future models incorporating novel biomarkers. The results showed that six validated models demonstrated good performance for predicting survival after resection of HCC.
Review
Surgery
Seong Wook Shin, Keun Soo Ahn, Sang Woo Kim, Tae-Seok Kim, Yong Hoon Kim, Koo Jeong Kang
Summary: This study found that liver resection (LR) is more effective than local ablation therapies (such as RFA, MWA, and RFA plus TACE) in treating HCC within the Milan criteria. Specifically, LR has better 5-year recurrence-free survival and lower local recurrence rates compared to local ablation therapies.
Review
Radiology, Nuclear Medicine & Medical Imaging
Tae-Hyung Kim, Sungmin Woo, Sangwon Han, Chong Hyun Suh, Richard Kinh Gian Do, Jeong Min Lee
Summary: This systematic review and meta-analysis aimed to identify the risk factors for hypervascularization in hepatocellular carcinoma patients with hepatobiliary phase hypointense nodules without arterial phase hyperenhancement. The results showed that nodules with baseline size greater than 10 mm, T2 hyperintensity, restricted diffusion, and previous history of hepatocellular carcinoma had a higher risk of hypervascularization.
ACADEMIC RADIOLOGY
(2022)
Article
Oncology
Sungmin Woo, Abdallah Araji, Mohammad Ali El Amine, Natalie Gangai, Elizabeth Acquafredda, Anita P. Price, Tanya M. Trippett, Hedvig Hricak, Hebert Alberto Vargas, Gerald G. Behr
Summary: A retrospective analysis was conducted on 261 pediatric cancer patients over a 5-year period to assess the modalities and findings of ER imaging. Positive ER imaging, common complaints related to chest and fever, and their association with inpatient admission and poorer survival were identified.
Review
Radiology, Nuclear Medicine & Medical Imaging
Tae-Hyung Kim, Sungmin Woo, Ijin Joo, Mustafa R. Bashir, Mi-Suk Park, Lauren M. B. Burke, Mishal Mendiratta-Lala, Richard K. G. Do
Summary: The LI-RADS TR algorithm demonstrates moderate sensitivity and high specificity for detecting incomplete necrosis after LRT, with arterial phase hyperenhancement being the dominant criterion. Washout contributes to the results to a meaningful extent, while enhancement similar to pretreatment may have a negligible contribution. The type of LRT may affect the algorithm's performance.
ABDOMINAL RADIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Sungmin Woo, Soleen Ghafoor, Anton S. Becker, Hedvig Hricak, Alvin C. Goh, Hebert Alberto Vargas
Summary: In patients with intradiverticular bladder tumors (IDBT), several MRI features were significantly associated with overall survival. Utilizing all available clinicopathological and imaging information may improve estimation of prognosis.
ACADEMIC RADIOLOGY
(2022)
Article
Oncology
Sungmin Woo, Chong Hyun Suh, Andreas G. Wibmer, Anton S. Becker, Min Yuen Teo, Mithat Gonen, Hedvig Hricak, Howard Scher, Michael J. Morris, Hebert Alberto Vargas
Summary: This study assessed the correlation between imaging-based intermediate endpoints (IBIEs) and overall survival in patients with metastatic castration-resistant prostate cancer. The overall correlation was good, with trials using radiographic progression-free survival showing higher correlation than those using a composite IBIE.
CLINICAL GENITOURINARY CANCER
(2022)
Review
Radiology, Nuclear Medicine & Medical Imaging
Ho Young Park, Chong Hyun Suh, Sungmin Woo, Pyeong Hwa Kim, Kyung Won Kim
Summary: This study evaluated the completeness of reporting in systematic reviews and meta-analyses published in the Korean Journal of Radiology using the PRISMA 2020 guidelines. The findings revealed that several items in the PRISMA 2020 checklist were overlooked in these articles. The authors suggest the use of a double-checklist to improve the quality of systematic reviews and meta-analyses.
KOREAN JOURNAL OF RADIOLOGY
(2022)
Article
Oncology
Sungmin Woo, Soleen Ghafoor, Jeeban P. Das, Natalie Gangai, Alvin C. Goh, Herbert Alberto Vargas
Summary: This study aimed to evaluate the MRI features of plasmacytoid urothelial carcinomas (PUC) of the bladder and their association with patient survival. The results showed that PUCs are typically large, diffuse tumors with features of extravesical extension (EVE) and pelvic peritoneal spread (PPS) on MRI, and these features are associated with survival.
UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS
(2022)
Article
Oncology
Lisa Marie Ruppert, Erica Dayan Cohn, Niamh M. Keegan, Abigail Bacharach, Sungmin Woo, Theresa Gillis, Howard I. Scher
Summary: Nonmalignant etiologies significantly contribute to back pain in patients with metastatic prostate cancer.
JCO ONCOLOGY PRACTICE
(2022)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Hebert Alberto Vargas, Sungmin Woo
Article
Oncology
Jeeban P. Das, Sungmin Woo, Soleen Ghafoor, P. I. Causa Andrieu, Gary A. Ulaner, Timothy F. Donahue, Alvin C. Goh, H. Alberto Vargas
Summary: This study evaluated the value of MRI in primary and recurrent UrC, showing high concordance between MRI Mayo stage and pathology, as well as in the detection of local recurrences.
UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Bernadette Z. Y. Wong, Pamela I. Causa Andrieu, Yukio Sonoda, Dennis S. Chi, Emeline M. Aviki, Hebert A. Vargas, Sungmin Woo
Summary: MRI and clinical features can differentiate malignant and benign O-RADS MRI score 4 adnexal masses. O-RADS MRI 4 lesions can be sub-stratified into high and low risk subgroups based on solid tissue characteristics and CA-125 levels.
EUROPEAN JOURNAL OF RADIOLOGY
(2023)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Sungmin Woo, Hebert A. Vargas
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2023)
Article
Oncology
Sungmin Woo, Anton S. Becker, Jeeban P. Das, Soleen Ghafoor, Yuki Arita, Nicole Benfante, Natalie Gangai, Min Yuen Teo, Alvin C. Goh, Hebert A. Vargas
Summary: BP-MRI is more accurate than MP-MRI in identifying residual disease after NAC in MIBC patients. A negative BP-MRI is associated with better outcomes and provides complementary information to pathological assessment of cystectomy specimens.
Article
Radiology, Nuclear Medicine & Medical Imaging
Monica Cheng, Pamela Causa Andrieu, Tae-Hyung Kim, Natalie Gangai, Yukio Sonoda, Hedvig Hricak, Yulia Lakhman, Hebert A. Vargas, Sungmin Woo
Summary: This retrospective study aimed to improve the O-RADS MRI scoring for fat-containing adnexal masses by investigating methods for quantifying solid tissue volume and fat distribution and evaluating their associations with malignancy.
ABDOMINAL RADIOLOGY
(2023)
Review
Radiology, Nuclear Medicine & Medical Imaging
Maria Clara Fernandes, Onur Yildirim, Sungmin Woo, Hebert Alberto Vargas, Hedvig Hricak
Summary: MRI plays an increasingly important role in the management of prostate cancer, aiding in accurate detection, staging, risk stratification, guided biopsy, treatment planning, and assessment of local recurrence and metastatic disease. Recent advancements in radiomics and artificial intelligence are being tested to improve detection and provide potential prognostic markers.
MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE
(2022)