Review
Agriculture, Dairy & Animal Science
Zitai Guo, Shengtao Gao, Jialiang Ouyang, Lu Ma, Dengpan Bu
Summary: Heat stress negatively affects milk protein synthesis in dairy cows, potentially by reducing appetite and dry matter intake, leading to oxidative stress and regulating apoptosis, reducing mammary epithelial cell numbers, and influencing endocrine function. Further research is needed to fully understand the mechanisms involved.
Article
Biochemistry & Molecular Biology
Xiuying Jiang, Xiangning Xu, Bicheng Wang, Ke Song, Jiaqi Zhang, Ye Chen, Ying Tian, Jing Weng, Yuanjing Liang, Wei Ma
Summary: 2-Methoxyestradiol (2-ME2), a metabolite of 17 beta-estradiol, is being studied as an antitumor agent. This study found that while 2-ME2 levels remain stable in the ovaries of aging mice, it declines in the serum. Exposure to 2-ME2 affects the meiotic maturation of mouse oocytes, leading to abnormal spindle structure and chromosome alignment. The study suggests that the impairment of oocyte maturation caused by 2-ME2 exposure is due to mitochondrial imbalance, oxidative stress, and apoptosis.
CHEMICO-BIOLOGICAL INTERACTIONS
(2023)
Review
Agriculture, Dairy & Animal Science
Eleni Dovolou, Themistoklis Giannoulis, Ioannis Nanas, Georgios S. Amiridis
Summary: Global warming poses a significant threat to the dairy sector, affecting both tropical and temperate regions. High temperatures compromise the welfare and fertility of dairy cows, leading to economic losses for farmers. Dairy cows employ various adaptive mechanisms to cope with heat stress, but the disruption of hormone secretion has long-lasting effects on fertility. Mitigation measures can restore milk production, but summer fertility records remain low due to the multifaceted nature of sustaining high fertility and proper reproductive processes.
Article
Agriculture, Dairy & Animal Science
Fernando Lopez-Gatius, Irina Garcia-Ispierto
Summary: This paper provides a clinical overview of luteal deficiency and its association with low fertility in dairy cows. Low plasma P4 concentrations during the luteal phase post-AI are linked to lower conception rates. Treatments with P4, GnRH, or hCG post-AI can improve fertility in certain conditions.
Article
Agriculture, Dairy & Animal Science
R. Rearte, S. G. Corva, R. L. de la Sota, I. M. Lacau-Mengido, M. J. Giuliodori
Summary: Poor udder health status has a negative impact on milk yield and reproductive performance in dairy cows. This study found that somatic cell count (SCC) is negatively associated with daily milk yield and the odds for conception in grazing dairy cows.
JOURNAL OF DAIRY SCIENCE
(2022)
Article
Environmental Sciences
Kang-Na Wei, Xin-Jie Wang, Zhao-Cheng Zeng, Ruo-Ting Gu, Shu-Zi Deng, Jiang Jiang, Chang-Long Xu, Wei Li, Hai-Long Wang
Summary: The study revealed the toxic effects of PFOS on mouse oocyte maturation, including reduced polar body extrusion rate and symmetrical cell division. PFOS caused abnormal cytoskeleton in oocytes, inhibited meiotic progression, and disrupted oocyte quality and histone modifications.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Review
Biochemistry & Molecular Biology
Roberto Gualtieri, Guruprasad Kalthur, Vincenza Barbato, Maddalena Di Nardo, Satish Kumar Adiga, Riccardo Talevi
Summary: Mitochondria play a crucial role in cell metabolism and ATP synthesis, while also being responsible for generating ROS and maintaining calcium homeostasis. Dysfunction in mitochondria can lead to oxidative stress, affecting cell function. Assisted reproductive technologies and cryopreservation may compromise mitochondrial function, impacting reproductive outcomes by affecting sperm and oocyte quality and fertilization dynamics.
Review
Agriculture, Dairy & Animal Science
M. L. Rhoads
Summary: Heat stress has severe consequences for agricultural production, and its impact is exacerbated by global warming. Climate change is predicted to lead to reproductive problems, decreased milk production, and overall productivity losses. Development of technologies and management strategies to improve animal production capacity and efficiency during heat stress is urgently needed.
Article
Agricultural Engineering
Jinghui Li, Vinod Narayanan, Ermias Kebreab, Serdal Dikmen, James G. Fadel
Summary: A dynamic model was developed to predict the thermal balance of Holstein dairy cattle, showing sensitivity to heat production, surface area, respiration, and sweating parameters. The model accurately simulated body temperatures under typical summer conditions in California, providing insights for the use of cooling strategies in dairy facilities.
BIOSYSTEMS ENGINEERING
(2021)
Article
Environmental Sciences
Hui-Li Wang, Guang-Dong Xing, Yong Qian, Xue-Feng Sun, Ji-Feng Zhong, Kun-Lin Chen
Summary: The study showed that Dihydromyricetin (DMY) can protect dairy cow mammary epithelial cells against heat stress-induced injury by preventing oxidative stress and balancing mitochondrial fission and fusion. This finding provides evidence for DMY as a potential therapeutic drug for treating heat stress-induced mammary gland injury and mastitis.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Article
Cell Biology
Dong Niu, Kun-Lin Chen, Yi Wang, Xiao-Qing Li, Lu Liu, Xiang Ma, Xing Duan
Summary: It has been found that exposure to HES can adversely affect oocyte quality, resulting in impaired oocyte maturation and abnormalities in mitochondrial function. Mitochondrial dysfunction and disruption in mitochondrial fission and fusion dynamics are believed to be major contributors to the reduced oocyte quality after HES exposure.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Article
Agriculture, Dairy & Animal Science
J. S. M. van der Laan, P. L. A. M. Vos, B. H. P. van den Borne, H. Aardema, T. van Werven
Summary: The study revealed that prostaglandins were the most commonly used reproductive hormone in Dutch dairy cows, followed by GnRH and progesterone. Participation in veterinary herd health management programs and the use of technologies like pedometers and automatic milking systems were associated with increased reproductive hormone use. Farms with automatic milking systems tended to use more reproductive hormones compared to those with conventional milking systems.
JOURNAL OF DAIRY SCIENCE
(2021)
Article
Environmental Sciences
Jian-Zhou Shang, Shi-Ru Li, Xiao-Qing Li, Yu-Ting Zhou, Xiang Ma, Lu Liu, Dong Niu, Xing Duan
Summary: Exposure to Simazine reduces oocyte maturation competence and embryonic developmental capacity, disrupts microtubule stability and actin polymerization, leading to mitochondrial dysfunction and apoptosis.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2022)
Article
Environmental Sciences
Chun-Hua Xing, Yue Wang, Jing-Cai Liu, Zhen-Nan Pan, Hao-Lin Zhang, Shao-Chen Sun, Yu Zhang
Summary: Sudan I, an industrial dye illegally used in food, poses toxic effects on mouse oocytes by disrupting spindle organization and inducing mitochondrial dysfunction. Melatonin supplementation can protect against Sudan I-induced meiotic deteriorations.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Article
Biotechnology & Applied Microbiology
Guangsheng Li, Xingtan Yu, Ananda B. Portela Fontoura, Awais Javaid, Victor Sainz de la Maza-Escola, Nia S. Salandy, Susan L. Fubini, Ester Grilli, Joseph. W. McFadden, Jingyue Ellie Duan
Summary: Through liver transcriptome analysis, we found 483 differentially expressed genes in her heat-stressed cows, especially significant downregulation of protein encoded genes in mitochondria. Furthermore, gene ontology enrichment analysis revealed an upregulation of protein folding pathway and a downregulation of oxidative phosphorylation pathway. This study provides important insights into the impact of heat stress on dairy cow health and productivity.
Article
Agriculture, Dairy & Animal Science
Roberta Ferreira Leite, Joao Diego de Agostini Losano, Giulia Kiyomi Vechiato Kawai, Bruno Rui, Ken Kawaoka Nagai, Vivian Cardoso Castiglioni, Adriano Felipe Perez Siqueira, Mayra Elena Ortiz D'Avila Assumpcao, Pietro Sampaio Baruselli, Marcilio Nichi
Summary: This study used conventional and functional techniques to evaluate sperm samples from bulls with known fertility history, revealing associations between mitochondrial dysfunctions, oxidative stress, and damage to sperm structures in lesser fertility bulls. Greater fertility bulls demonstrated better sperm quality and indicators of functional cell structures. The importance of evaluating and correlating different sperm functions to understand the effects of distinct parameters on sperm fertilization capacity was highlighted.
ANIMAL REPRODUCTION SCIENCE
(2022)
Article
Agriculture, Dairy & Animal Science
R. B. Paiano, L. Z. Moreno, V. T. M. Gomes, B. M. Parra, M. R. Barbosa, M. I. Z. Sato, J. Bonilla, G. Pugliesi, P. S. Baruselli, A. M. Moreno
Summary: This study aimed to identify the main bacteria related to clinical and subclinical endometritis in dairy cows in Brazilian herds. The results revealed that specific bacterial infections were associated with these diseases, and the composition of bacteria varied among different groups.
JOURNAL OF DAIRY SCIENCE
(2022)
Review
Developmental Biology
Pietro S. Baruselli, Carlos A. Rodrigues, Roberta M. Ferreira, Jose Nelio S. Sales, Flavia M. Elliff, Laisa G. Silva, Mariana P. Viziack, Luana Factor, Michael J. D'Occhio
Summary: The combination of genomic selection and in vitro embryo production (IVEP) using oocytes from heifer calves offers a powerful technology platform to reduce generation intervals and increase genetic gains in cattle. While heifer calves exhibit a good follicular response to FSH stimulation and oocyte retrieval through ovum pick-up (OPU), the efficiency of OPU/IVEP remains lower compared to peripubertal heifers and cows. Indicus cattle tend to have more follicles and achieve a better outcome in IVEP compared to taurus cattle. Ongoing optimization is needed to fully realize the potential of OPU/IVEP in young donors.
REPRODUCTION FERTILITY AND DEVELOPMENT
(2022)
Article
Biology
Vanessa Cristina de Oliveira, Kelly Cristine Santos Roballo, Clesio Gomes Mariano Junior, Sarah Ingrid Pinto Santos, Fabiana Fernandes Bressan, Marcos Roberto Chiaratti, Elena J. Tucker, Erica E. Davis, Jean-Paul Concordet, Carlos Eduardo Ambrosio
Summary: This study investigated the effects of CRISPR-Cas9 gene editing of TFAM in HEK293T cells on mtDNA copy number. The findings suggest that editing TFAM can decrease mtDNA copy number and interfere with mitochondrial stability and maintenance.
Article
Agriculture, Dairy & Animal Science
Bismarck M. Santiago, Welder A. Baldassini, Marcos R. Chiaratti, Anand K. Pandey, Juliana A. Torrecilhas, Rodrigo N. S. Torres, Richard Ribeiro, Dante P. D. Lanna, Guilherme L. Pereira, Rogerio A. Curi, Luis Artur L. Chardulo, Otavio R. Machado Neto
Summary: This study analyzed the impact of castration on the expression of genes in skeletal muscles and the quality of beef. Results showed that castrated steers had increased expression of genes related to fat metabolism compared to intact bulls. This led to higher intramuscular fat content and different fatty acid profiles in the beef produced by steers and bulls. Despite a 180-day feeding period, crossbred bulls did not exhibit substantial increases in intramuscular fat or improved fatty acid profile compared to steers.
Article
Agriculture, Dairy & Animal Science
Renan Braga Paiano, Jeannine Bonilla, Guilherme Pugliesi, Andrea Micke Moreno, Pietro Sampaio Baruselli
Summary: Clinical endometritis (CE) and subclinical endometritis (SE) are two uterine diseases that can affect milk production and fertility in dairy cows during the puerperium period. This study found that cows with CE and SE had lower conception rates and milk production, but no effect on milk production during 305 DIM. Furthermore, cows with CE and SE but negative bacteria isolation did not have impaired reproductive performance and milk production during the postpartum period.
REPRODUCTION IN DOMESTIC ANIMALS
(2023)
Article
Reproductive Biology
Angelica C. dos Santos, Daniel C. Joaquim, Ricardo P. Nociti, Carolina H. Macabelli, Rafael V. Sampaio, Aline S. Oliveira, Maico O. Pita, Robinson A. M. de Oliveira, Juliano C. da Silveira, Flavio V. Meirelles, Osnir Y. Watanabe, Yeda F. Watanabe, Marcos R. Chiaratti
Summary: Micro-vibration treatment during in vitro embryo culture improves the cryoresistance of bovine embryos, but it may also lead to epigenetic and transcriptional abnormalities.
Article
Reproductive Biology
Renan B. Paiano, Ricardo L. M. de Sousa, Jeannine Bonilla, Luisa Z. Moreno, Evandro D. F. de Souza, Pietro S. Baruselli, Andrea M. Moreno
Summary: Clinical endometritis in dairy cows has negative effects on fertility and milk production, and causes additional treatment costs. This study evaluated the antibacterial activity of cinnamon, oregano, and thyme essential oils, alone and in combination, against bovine uterine pathogens. Cinnamon essential oil showed the lowest Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) values. The study suggests that cinnamon essential oil has promising antimicrobial activity and could be explored as an alternative treatment for clinical endometritis in dairy cows.
Article
Biochemistry & Molecular Biology
German Dario Ramirez-Zamudio, Maria Julia Generoso Ganga, Guilherme Luis Pereira, Ricardo Perecin Nociti, Marcos Roberto Chiaratti, Reinaldo Fernandes Cooke, Luis Artur Loyola Chardulo, Welder Angelo Baldassini, Otavio Rodrigues Machado-Neto, Rogerio Abdallah Curi
Summary: The aim of this study was to analyze the effects of different diets on adipogenesis and lipogenesis in calves. It was found that calves receiving creep feeding had higher intramuscular fat content and marbling score compared to those without creep feeding. Differentially expressed genes related to fatty acid metabolism, cholesterol biosynthesis, and insulin sensitivity were identified.
Article
Biochemical Research Methods
Bismarck Santiago, Welder Baldassini, Otavio Machado Neto, Luis Artur Chardulo, Rodrigo Torres, Guilherme Pereira, Rogerio Curi, Marcos Roberto Chiaratti, Pedro Padilha, Laura Alessandroni, Mohammed Gagaoua
Summary: This study investigated the skeletal muscle proteome of crossbred bulls and steers to explain the differences in carcass and meat quality traits. The results showed that steers had better meat quality, while bulls had higher carcass fatness. The proteomic analysis revealed differences in protein expression related to energy metabolism, catabolic processes, oxidative stress, and muscle contraction.
JOURNAL OF PROTEOMICS
(2023)
Article
Multidisciplinary Sciences
Luciano A. Gonzalez, Julia G. S. Carvalho, Bruno C. Kuinchtner, Anthony C. Dona, Pietro S. Baruselli, Michael J. D'Occhio
Summary: H-1 NMR-based metabolomics was used to study the effect of abrupt weaning on the blood metabolome of beef calves. The study found that calves experienced acute stress in the first 2 days after weaning, with changes in behavior and increased cortisol levels. Long-term metabolic changes were also observed, including increased carbohydrate metabolism and decreased lipid metabolism.
SCIENTIFIC REPORTS
(2023)
Article
Agriculture, Dairy & Animal Science
Joedson Dantas Goncalves, Jose Bento Sterman Ferraz, Flavio Vieira Meirelles, Ricardo Perecin Nociti, Maria Emilia Franco Oliveira
Summary: Our study compared the mechanisms of cervical dilation in sheep and cows in different phases of the reproductive cycle. We found differences in gene expression between the follicular and luteal phases in both species. The PI3K/Akt pathway was identified as an important mechanism in cervical relaxation.
Review
Agriculture, Dairy & Animal Science
Pietro S. Baruselli, Nelcio A. T. de Carvalho, Bianca Gasparrini, Giuseppe Campanile, Michael J. D'Occhio
Summary: The domestic buffalo, also known as water buffalo, is a globally significant livestock species. It includes two sub-species, the River buffalo and the Swamp buffalo. The River buffalo is a primary source of milk and meat in South Asia and supports high-value food production in Europe and the Americas. The Swamp buffalo is important for draft work and food in Southeast Asia and East Asia. The use of assisted reproduction, such as artificial insemination and embryo technologies, is becoming increasingly important for genetic improvement in buffaloes.
Article
Agriculture, Dairy & Animal Science
Bruna Lima Chechin Catussi, Claudiney de Melo, Laisa Garcia da Silva, Lais Angelo de Abreu, William Koury Filho, Raysildo Barbosa Lobo, Michael John D'Occhio, Pietro Sampaio Baruselli
Summary: This study evaluated the effects of nutrition and genetic selection for early puberty on the reproductive response of Nelore heifers. The results showed that improved nutrition and high genetic group had higher pregnancy rate and embryo production compared to moderate nutrition and low genetic group.
Meeting Abstract
Agriculture, Dairy & Animal Science
R. Sartori, N. P. Folchini, D. Demetrio, P. S. Baruselli
JOURNAL OF DAIRY SCIENCE
(2022)