Efficacy and harms of long‐term opioid therapy in chronic non‐cancer pain: Systematic review and meta‐analysis of open‐label extension trials with a study duration ≥26 weeks

Efficacy and safety of controlled-release oxycodone for the management of moderate-to-severe chronic low back pain in Japan: results of an enriched enrollment randomized withdrawal study followed by an open-label extension study

(2019) Mikito Kawamata et al.   Journal of Pain Research

Association of Tramadol With All-Cause Mortality Among Patients With Osteoarthritis

(2019) Chao Zeng et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Opioid Crisis: No Easy Fix to Its Social and Economic Determinants

(2018) Nabarun Dasgupta et al.   AMERICAN JOURNAL OF PUBLIC HEALTH

Methodologic limitations of prescription opioid safety research and recommendations for improving the evidence base

(2018) Shabbar I. Ranapurwala et al.   PHARMACOEPIDEMIOLOGY AND DRUG SAFETY

Prescription opioid analgesic use in France: Trends and impact on morbidity-mortality

(2018) C. Chenaf et al.   EUROPEAN JOURNAL OF PAIN

Prevention and Treatment of Opioid Misuse and Addiction

(2018) Nora D. Volkow et al.   JAMA Psychiatry

Comparison of Opioid Prescribing Patterns in the United States and Japan: Primary Care Physicians' Attitudes and Perceptions

(2017) Eriko Onishi et al.   Journal of the American Board of Family Medicine

Are Prescription Opioids Driving the Opioid Crisis? Assumptions vs Facts

(2017) Mark Edmund Rose   PAIN MEDICINE

Long-term safety and analgesic efficacy of buprenorphine buccal film in patients with moderate-to-severe chronic pain requiring around-the-clock opioids

(2017) Martin Hale et al.   Journal of Pain Research

European Pain Federation position paper on appropriate opioid use in chronic pain management

(2016) T. O'Brien et al.   EUROPEAN JOURNAL OF PAIN

Prescription of Long-Acting Opioids and Mortality in Patients With Chronic Noncancer Pain

(2016) Wayne A. Ray et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

CDC Guideline for Prescribing Opioids for Chronic Pain—United States, 2016

(2016) Deborah Dowell et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

A Randomized, Double-Blind, Crossover Comparison of the Efficacy and Safety of Oral Controlled-Release Tramadol and Placebo in Patients with Painful Osteoarthritis

(2016) Carter Thorne et al.   Pain Research & Management

Controlled-Release Oxycodone and Naloxone in the Treatment of Chronic Low Back Pain: A Placebo-Controlled, Randomized Study

(2016) C Cloutier et al.   Pain Research & Management

The Effectiveness and Risks of Long-Term Opioid Therapy for Chronic Pain: A Systematic Review for a National Institutes of Health Pathways to Prevention Workshop

(2015) Roger Chou et al.   ANNALS OF INTERNAL MEDICINE

Long-term Safety and Efficacy of Tapentadol Extended Release Following up to 2 Years of Treatment in Patients With Moderate to Severe, Chronic Pain: Results of an Open-label Extension Trial

(2015) Robert Buynak et al.   CLINICAL THERAPEUTICS

Rates of opioid misuse, abuse, and addiction in chronic pain

(2015) Kevin E. Vowles et al.   PAIN

Long-term evaluation of combined prolonged-release oxycodone and naloxone in patients with moderate-to-severe chronic pain: pooled analysis of extension phases of two Phase III trials

(2014) M. Blagden et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Abuse liability measures for use in analgesic clinical trials in patients with pain: IMMPACT recommendations

(2013) Alec B. O’Connor et al.   PAIN

Opioid Dependence vs Addiction

(2012) Jane C. Ballantyne et al.   ARCHIVES OF INTERNAL MEDICINE

Sustained Safety and Efficacy of Once-Daily Hydromorphone Extended-Release (OROS®hydromorphone ER) Compared with Twice-Daily Oxycodone Controlled-Release Over 52 Weeks in Patients with Moderate to Severe Chronic Noncancer Pain

(2012) Ute Richarz et al.   Pain Practice

Risk factors for drug dependence among out-patients on opioid therapy in a large US health-care system

(2010) Joseph A. Boscarino et al.   ADDICTION

Buprenorphine transdermal system in adults with chronic low back pain: A randomized, double-blind, placebo-controlled crossover study, followed by an open-label extension phase

(2010) Allan Gordon et al.   CLINICAL THERAPEUTICS

Long-term efficacy and safety of combined prolonged-release oxycodone and naloxone in the management of non-cancer chronic pain

(2010) A. Sandner-Kiesling et al.   INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

“Evidence” in chronic pain – establishing best practice in the reporting of systematic reviews

(2010) Andrew R. Moore et al.   PAIN