Optogenetic and chemogenetic insights into the neurocircuitry of depression‐like behaviour: A systematic review

HCN2 Channels in Cholinergic Interneurons of Nucleus Accumbens Shell Regulate Depressive Behaviors

(2019) Jia Cheng et al.   NEURON

Different roles of distinct serotonergic pathways in anxiety-like behavior, antidepressant-like, and anti-impulsive effects

(2019) Yu Ohmura et al.   NEUROPHARMACOLOGY

Dorsal raphe projection inhibits the excitatory inputs on lateral habenula and alleviates depressive behaviors in rats

(2018) Hai Zhang et al.   Brain Structure & Function

Brain circuits mediating opposing effects on emotion and pain

(2018) You-Qing Cai et al.   JOURNAL OF NEUROSCIENCE

Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: a systematic review and network meta-analysis

(2018) Andrea Cipriani et al.   LANCET

Stimulation of entorhinal cortex–dentate gyrus circuitry is antidepressive

(2018) Sanghee Yun et al.   NATURE MEDICINE

Treatment resistant depression: A multi-scale, systems biology approach

(2018) Huda Akil et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

A neural pathway controlling motivation to exert effort

(2018) Christophe D. Proulx et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inability to suppress the stress-induced activation of the HPA axis during the peripartum period engenders deficits in postpartum behaviors in mice

(2018) Laverne Camille Melón et al.   PSYCHONEUROENDOCRINOLOGY

Alpha1 and beta3 adrenergic receptor-mediated mesolimbic homeostatic plasticity confers resilience to social stress in susceptible mice

(2018) Hongxing Zhang et al.   BIOLOGICAL PSYCHIATRY

Glutamine has antidepressive effects through increments of glutamate and glutamine levels and glutamatergic activity in the medial prefrontal cortex

(2018) Hyeonwi Son et al.   NEUROPHARMACOLOGY

SSRIs target prefrontal to raphe circuits during development modulating synaptic connectivity and emotional behavior

(2018) M. Soiza-Reilly et al.   MOLECULAR PSYCHIATRY

Wiring the depressed brain: optogenetic and chemogenetic circuit interrogation in animal models of depression

(2018) Jessie Muir et al.   NEUROPSYCHOPHARMACOLOGY

Manipulation of dorsal raphe serotonergic neurons modulates active coping to inescapable stress and anxiety-related behaviors in mice and rats

(2018) Naoya Nishitani et al.   NEUROPSYCHOPHARMACOLOGY

Mesopontine cholinergic inputs to midbrain dopamine neurons drive stress-induced depressive-like behaviors

(2018) Sebastian P. Fernandez et al.   Nature Communications

Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

(2017) Theo Vos et al.   LANCET

In Vivo Fiber Photometry Reveals Signature of Future Stress Susceptibility in Nucleus Accumbens

(2017) Jessie Muir et al.   NEUROPSYCHOPHARMACOLOGY

A standardization of the Novelty-Suppressed Feeding Test protocol in rats

(2017) Arantxa Blasco-Serra et al.   NEUROSCIENCE LETTERS

Limiting habenular hyperactivity ameliorates maternal separation-driven depressive-like symptoms

(2017) Anna Tchenio et al.   Nature Communications

Synaptic Regulation of a Thalamocortical Circuit Controls Depression-Related Behavior

(2017) Oliver H. Miller et al.   Cell Reports

Essential Role of Mesolimbic Brain-Derived Neurotrophic Factor in Chronic Social Stress–Induced Depressive Behaviors

(2016) Ja Wook Koo et al.   BIOLOGICAL PSYCHIATRY

DREADD in Parvalbumin Interneurons of the Dentate Gyrus Modulates Anxiety, Social Interaction and Memory Extinction

(2016) D. Zou et al.   CURRENT MOLECULAR MEDICINE

A Basal Forebrain Site Coordinates the Modulation of Endocrine and Behavioral Stress Responses via Divergent Neural Pathways

(2016) Shane B. Johnson et al.   JOURNAL OF NEUROSCIENCE

DREADDs for Neuroscientists

(2016) Bryan L. Roth   NEURON

An overview of maternal separation effects on behavioural outcomes in mice: Evidence from a four-stage methodological systematic review

(2016) Saulo G. Tractenberg et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

The Use of DREADDs to Deconstruct Behavior

(2016) Paul D. Whissell et al.   Frontiers in Genetics

Top-Down Control of Serotonin Systems by the Prefrontal Cortex: A Path toward Restored Socioemotional Function in Depression

(2015) Collin Challis et al.   ACS Chemical Neuroscience

Nucleus Accumbens Medium Spiny Neuron Subtypes Mediate Depression-Related Outcomes to Social Defeat Stress

(2015) T. Chase Francis et al.   BIOLOGICAL PSYCHIATRY

Depression of Excitatory Synapses onto Parvalbumin Interneurons in the Medial Prefrontal Cortex in Susceptibility to Stress

(2015) Z. Perova et al.   JOURNAL OF NEUROSCIENCE

Activation of a ventral hippocampus–medial prefrontal cortex pathway is both necessary and sufficient for an antidepressant response to ketamine

(2015) F R Carreno et al.   MOLECULAR PSYCHIATRY

Daytime spikes in dopaminergic activity drive rapid mood-cycling in mice

(2015) M M Sidor et al.   MOLECULAR PSYCHIATRY

Activating positive memory engrams suppresses depression-like behaviour

(2015) Steve Ramirez et al.   NATURE

Stress effects on the neural substrates of motivated behavior

(2015) Nick G Hollon et al.   NATURE NEUROSCIENCE

Optogenetics: 10 years of microbial opsins in neuroscience

(2015) Karl Deisseroth   NATURE NEUROSCIENCE

A New DREADD Facilitates the Multiplexed Chemogenetic Interrogation of Behavior

(2015) Eyal Vardy et al.   NEURON

Elucidation of The Behavioral Program and Neuronal Network Encoded by Dorsal Raphe Serotonergic Neurons

(2015) Daniel J Urban et al.   NEUROPSYCHOPHARMACOLOGY

The mediodorsal thalamus as a higher order thalamic relay nucleus important for learning and decision-making

(2015) Anna S. Mitchell   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Optogenetic stimulation of infralimbic PFC reproduces ketamine’s rapid and sustained antidepressant actions

(2015) Manabu Fuchikami et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The ventral pallidum: Subregion-specific functional anatomy and roles in motivated behaviors

(2015) David H. Root et al.   PROGRESS IN NEUROBIOLOGY

Ventral hippocampal afferents to the nucleus accumbens regulate susceptibility to depression

(2015) Rosemary C. Bagot et al.   Nature Communications

Activity of Raphé Serotonergic Neurons Controls Emotional Behaviors

(2015) Anne Teissier et al.   Cell Reports

Are child and adolescent mental health problems increasing in the 21st century? A systematic review

(2014) William Bor et al.   AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY

Conditional anterograde tracing reveals distinct targeting of individual serotonin cell groups (B5–B9) to the forebrain and brainstem

(2014) Aude Muzerelle et al.   Brain Structure & Function

Cyclin-Dependent Kinase 5 in the Ventral Tegmental Area Regulates Depression-Related Behaviors

(2014) P. Zhong et al.   JOURNAL OF NEUROSCIENCE

Prefrontal Cortical Circuit for Depression- and Anxiety-Related Behaviors Mediated by Cholecystokinin: Role of  FosB

(2014) V. Vialou et al.   JOURNAL OF NEUROSCIENCE

Postnatal Day 2 to 11 Constitutes a 5-HT-Sensitive Period Impacting Adult mPFC Function

(2014) T. J. Rebello et al.   JOURNAL OF NEUROSCIENCE

Noninvasive optical inhibition with a red-shifted microbial rhodopsin

(2014) Amy S Chuong et al.   NATURE NEUROSCIENCE

Reward processing by the lateral habenula in normal and depressive behaviors

(2014) Christophe D Proulx et al.   NATURE NEUROSCIENCE

Opposing Effects of Acute versus Chronic Blockade of Frontal Cortex Somatostatin-Positive Inhibitory Neurons on Behavioral Emotionality in Mice

(2014) Amelie Soumier et al.   NEUROPSYCHOPHARMACOLOGY

Optogenetics to study the circuits of fear- and depression-like behaviors: A critical analysis

(2014) Catherine Belzung et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Enhancing Depression Mechanisms in Midbrain Dopamine Neurons Achieves Homeostatic Resilience

(2014) A. K. Friedman et al.   SCIENCE

Optogenetic modulation of descending prefrontocortical inputs to the dorsal raphe bidirectionally bias socioaffective choices after social defeat

(2014) Collin Challis et al.   Frontiers in Behavioral Neuroscience

Recent advances in optogenetics and pharmacogenetics

(2013) Gary Aston-Jones et al.   BRAIN RESEARCH

DREADDs: novel tools for drug discovery and development

(2013) Hyeong-Min Lee et al.   DRUG DISCOVERY TODAY

Impaired periamygdaloid-cortex prodynorphin is characteristic of opiate addiction and depression

(2013) Sarah Ann R. Anderson et al.   JOURNAL OF CLINICAL INVESTIGATION

Cortical Control of Affective Networks

(2013) S. Kumar et al.   JOURNAL OF NEUROSCIENCE

Raphe GABAergic Neurons Mediate the Acquisition of Avoidance after Social Defeat

(2013) C. Challis et al.   JOURNAL OF NEUROSCIENCE

Global burden of disease attributable to mental and substance use disorders: findings from the Global Burden of Disease Study 2010

(2013) Harvey A Whiteford et al.   LANCET

Stress and CRF gate neural activation of BDNF in the mesolimbic reward pathway

(2013) Jessica J Walsh et al.   NATURE NEUROSCIENCE

Forebrain-specific deletion of Cdk5 in pyramidal neurons results in mania-like behavior and cognitive impairment

(2013) Susan C. Su et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Impaired Prefronto-Thalamic Functional Connectivity as a Key Feature of Treatment-Resistant Depression: A Combined MEG, PET and rTMS Study

(2013) Cheng-Ta Li et al.   PLoS One

From Optogenetic Technologies to Neuromodulation Therapies

(2013) J. C. Williams et al.   Science Translational Medicine

Brain-Derived Neurotrophic Factor Signaling and Subgenual Anterior Cingulate Cortex Dysfunction in Major Depressive Disorder

(2012) Adam Tripp et al.   AMERICAN JOURNAL OF PSYCHIATRY

Different stressors produce excitation or inhibition of mesolimbic dopamine neuron activity: response alteration by stress pre-exposure

(2012) Ornella Valenti et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Dopaminergic Mechanisms of Individual Differences in Human Effort-Based Decision-Making

(2012) M. T. Treadway et al.   JOURNAL OF NEUROSCIENCE

A prefrontal cortex–brainstem neuronal projection that controls response to behavioural challenge

(2012) Melissa R. Warden et al.   NATURE

Input-specific control of reward and aversion in the ventral tegmental area

(2012) Stephan Lammel et al.   NATURE

Dopamine neurons modulate neural encoding and expression of depression-related behaviour

(2012) Kay M. Tye et al.   NATURE

Rapid regulation of depression-related behaviours by control of midbrain dopamine neurons

(2012) Dipesh Chaudhury et al.   NATURE

The Logic of Inhibitory Connectivity in the Neocortex

(2012) Elodie Fino et al.   NEUROSCIENTIST

Chronic social defeat stress model: behavioral features, antidepressant action, and interaction with biological risk factors

(2012) E. Venzala et al.   PSYCHOPHARMACOLOGY

The Long-Term Health Consequences of Child Physical Abuse, Emotional Abuse, and Neglect: A Systematic Review and Meta-Analysis

(2012) Rosana E. Norman et al.   PLOS MEDICINE

Depression, Hypothalamic Pituitary Adrenal Axis, and Hippocampal and Entorhinal Cortex Volumes—The SMART Medea Study

(2011) Lotte Gerritsen et al.   BIOLOGICAL PSYCHIATRY

Increased Cdk5/p35 activity in the dentate gyrus mediates depressive-like behaviour in rats

(2011) Wei-Li Zhu et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

GABA-related transcripts in the dorsolateral prefrontal cortex in mood disorders

(2011) Etienne Sibille et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Negative Reward Signals from the Lateral Habenula to Dopamine Neurons Are Mediated by Rostromedial Tegmental Nucleus in Primates

(2011) S. Hong et al.   JOURNAL OF NEUROSCIENCE

Molecular evidence for BDNF- and GABA-related dysfunctions in the amygdala of female subjects with major depression

(2011) J-P Guilloux et al.   MOLECULAR PSYCHIATRY

A standardized protocol for repeated social defeat stress in mice

(2011) Sam A Golden et al.   Nature Protocols

Optogenetics in Neural Systems

(2011) Ofer Yizhar et al.   NEURON

Disentangling pleasure from incentive salience and learning signals in brain reward circuitry

(2011) K. S. Smith et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neural circuits underlying the pathophysiology of mood disorders

(2011) Joseph L. Price et al.   TRENDS IN COGNITIVE SCIENCES

Medial prefrontal cortex and the self in major depression

(2010) Cédric Lemogne et al.   JOURNAL OF AFFECTIVE DISORDERS

Antidepressant Effect of Optogenetic Stimulation of the Medial Prefrontal Cortex

(2010) H. E. Covington et al.   JOURNAL OF NEUROSCIENCE

Mesolimbic Dopamine Neurons in the Brain Reward Circuit Mediate Susceptibility to Social Defeat and Antidepressant Action

(2010) J.-L. Cao et al.   JOURNAL OF NEUROSCIENCE

Optogenetics

(2010) Karl Deisseroth   NATURE METHODS

ΔFosB in brain reward circuits mediates resilience to stress and antidepressant responses

(2010) Vincent Vialou et al.   NATURE NEUROSCIENCE

Optogenetic interrogation of neural circuits: technology for probing mammalian brain structures

(2010) Feng Zhang et al.   Nature Protocols

Are the Dorsal and Ventral Hippocampus Functionally Distinct Structures?

(2010) Michael S. Fanselow et al.   NEURON

Depression, rumination and the default network

(2010) Marc G. Berman et al.   Social Cognitive and Affective Neuroscience

Antidepressant-Like Effects of Medial Prefrontal Cortex Deep Brain Stimulation in Rats

(2009) Clement Hamani et al.   BIOLOGICAL PSYCHIATRY

Dynorphin, stress, and depression

(2009) Allison T. Knoll et al.   BRAIN RESEARCH

Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement

(2009) David Moher et al.   JOURNAL OF CLINICAL EPIDEMIOLOGY

Targeted electrode-based modulation of neural circuits for depression

(2009) Helen S. Mayberg   JOURNAL OF CLINICAL INVESTIGATION

The Rostromedial Tegmental Nucleus (RMTg), a GABAergic Afferent to Midbrain Dopamine Neurons, Encodes Aversive Stimuli and Inhibits Motor Responses

(2009) Thomas C. Jhou et al.   NEURON

Neurocircuitry of Mood Disorders

(2009) Joseph L Price et al.   NEUROPSYCHOPHARMACOLOGY

Prefrontal afferents to the dorsal raphe nucleus in the rat

(2008) Luciano Gonçalves et al.   BRAIN RESEARCH BULLETIN

The Anteroventral Bed Nucleus of the Stria Terminalis Differentially Regulates Hypothalamic-Pituitary-Adrenocortical Axis Responses to Acute and Chronic Stress

(2007) Dennis C. Choi et al.   ENDOCRINOLOGY