Genetically engineered distal airway stem cell transplantation protects mice from pulmonary infection

Distal airway stem cells ameliorate bleomycin-induced pulmonary fibrosis in mice

(2019) Yun Shi et al.   Stem Cell Research & Therapy

Acidosis exacerbates in vivo IL-1-dependent inflammatory responses and neutrophil recruitment during pulmonary Pseudomonas aeruginosa infection

(2018) Iviana M. Torres et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Spatial-Temporal Lineage Restrictions of Embryonic p63 + Progenitors Establish Distinct Stem Cell Pools in Adult Airways

(2018) Ying Yang et al.   DEVELOPMENTAL CELL

Single-cell Wnt signaling niches maintain stemness of alveolar type 2 cells

(2018) Ahmad N. Nabhan et al.   SCIENCE

Regeneration of functional alveoli by adult human SOX9+ airway basal cell transplantation

(2018) Qiwang Ma et al.   Protein & Cell

Long-Term Culture of Distal Airway Epithelial Cells Allows Differentiation Towards Alveolar Epithelial Cells Suited for Influenza Virus Studies

(2018) Aki Imai-Matsushima et al.   EBioMedicine

Regeneration of the lung alveolus by an evolutionarily conserved epithelial progenitor

(2018) William J. Zacharias et al.   NATURE

Therapeutic T cell engineering

(2017) Michel Sadelain et al.   NATURE

Local lung hypoxia determines epithelial fate decisions during alveolar regeneration

(2017) Ying Xi et al.   NATURE CELL BIOLOGY

Regenerative potential of human airway stem cells in lung epithelial engineering

(2016) Sarah E. Gilpin et al.   BIOMATERIALS

Cathelicidins Have Direct Antiviral Activity against Respiratory Syncytial Virus In Vitro and Protective Function In Vivo in Mice and Humans

(2016) Silke M. Currie et al.   JOURNAL OF IMMUNOLOGY

Increased serum levels of LL37, HMGB1 and S100A9 during exacerbation in COPD patients

(2015) S. D. Pouwels et al.   EUROPEAN RESPIRATORY JOURNAL

p63+Krt5+ distal airway stem cells are essential for lung regeneration

(2014) Wei Zuo et al.   NATURE

Lineage-negative progenitors mobilize to regenerate lung epithelium after major injury

(2014) Andrew E. Vaughan et al.   NATURE

Fast and sensitive protein alignment using DIAMOND

(2014) Benjamin Buchfink et al.   NATURE METHODS

Cathelicidin Host Defence Peptide Augments Clearance of Pulmonary Pseudomonas aeruginosa Infection by Its Influence on Neutrophil Function In Vivo

(2014) Paula E. Beaumont et al.   PLoS One

Treatment with LL-37 is safe and effective in enhancing healing of hard-to-heal venous leg ulcers: a randomized, placebo-controlled clinical trial

(2014) Alvar Grönberg et al.   WOUND REPAIR AND REGENERATION

Type 2 alveolar cells are stem cells in adult lung

(2013) Christina E. Barkauskas et al.   JOURNAL OF CLINICAL INVESTIGATION

A comprehensive summary of LL-37, the factotum human cathelicidin peptide

(2012) Dieter Vandamme et al.   CELLULAR IMMUNOLOGY

Cathelicidin-Related Antimicrobial Peptide Is Required for Effective Lung Mucosal Immunity in Gram-Negative Bacterial Pneumonia

(2012) M. A. Kovach et al.   JOURNAL OF IMMUNOLOGY

An Official American Thoracic Society Workshop Report: Features and Measurements of Experimental Acute Lung Injury in Animals

(2011) Gustavo Matute-Bello et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Distal Airway Stem Cells Yield Alveoli In Vitro and during Lung Regeneration following H1N1 Influenza Infection

(2011) Pooja A. Kumar et al.   CELL

Designing antimicrobial peptides: form follows function

(2011) Christopher D. Fjell et al.   NATURE REVIEWS DRUG DISCOVERY

The Human Airway Epithelial Basal Cell Transcriptome

(2011) Neil R. Hackett et al.   PLoS One

Flagellin Stimulates Protective Lung Mucosal Immunity: Role of Cathelicidin-Related Antimicrobial Peptide

(2010) F.-s. Yu et al.   JOURNAL OF IMMUNOLOGY

Tissue-Engineered Lungs for in Vivo Implantation

(2010) T. H. Petersen et al.   SCIENCE

Potential of immunomodulatory host defense peptides as novel anti-infectives

(2009) Donna M. Easton et al.   TRENDS IN BIOTECHNOLOGY

The roles of cathelicidin LL-37 in immune defences and novel clinical applications

(2008) Anastasia Nijnik et al.   CURRENT OPINION IN HEMATOLOGY

Human Host Defense Peptide LL-37 Prevents Bacterial Biofilm Formation

(2008) J. Overhage et al.   INFECTION AND IMMUNITY