Comparative Proteomics Analysis of Human Liver Microsomes and S9 Fractions

Quantification of Proteins Involved in Drug Metabolism and Disposition in the Human Liver Using Label-Free Global Proteomics

(2019) Narciso Couto et al.   MOLECULAR PHARMACEUTICS

Label-free absolute protein quantification with data-independent acquisition

(2019) Bing He et al.   Journal of Proteomics

Toward a Consensus on Applying Quantitative Liquid Chromatography‐Tandem Mass Spectrometry Proteomics in Translational Pharmacology Research: A White Paper

(2019) Bhagwat Prasad et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Comparison of protein expression between human livers and the hepatic cell lines HepG2, Hep3B, and Huh7 using SWATH and MRM-HR proteomics: Focusing on drug-metabolizing enzymes

(2018) Jian Shi et al.   Drug Metabolism and Pharmacokinetics

Toward an understanding of the protein interaction network of the human liver

(2017) Jian Wang et al.   Molecular Systems Biology

SLC transporters as therapeutic targets: emerging opportunities

(2015) Lawrence Lin et al.   NATURE REVIEWS DRUG DISCOVERY

CES1 genetic variation affects the activation of angiotensin-converting enzyme inhibitors

(2015) X Wang et al.   PHARMACOGENOMICS JOURNAL

SWATH enables precise label-free quantification on proteome scale

(2015) Qiang Huang et al.   PROTEOMICS

Absolute protein quantification of clinically relevant cytochrome P450 enzymes and UDP-glucuronosyltransferases by mass spectrometry-based targeted proteomics

(2014) C. Gröer et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

A “Proteomic Ruler” for Protein Copy Number and Concentration Estimation without Spike-in Standards

(2014) Jacek R. Wiśniewski et al.   MOLECULAR & CELLULAR PROTEOMICS

MicroRNAs as regulators of drug transporters, drug-metabolizing enzymes, and tight junctions: Implication for intestinal barrier function

(2014) Kenji Ikemura et al.   PHARMACOLOGY & THERAPEUTICS

Quantitative analysis of cytochrome P450 isoforms in human liver microsomes by the combination of proteomics and chemical probe-based assay

(2014) Xidong Liu et al.   PROTEOMICS

Targeted Quantitative Proteomics for the Analysis of 14 UGT1As and -2Bs in Human Liver Using NanoUPLC–MS/MS with Selected Reaction Monitoring

(2013) John K. Fallon et al.   JOURNAL OF PROTEOME RESEARCH

An old method facing a new challenge: Re-visiting housekeeping proteins as internal reference control for neuroscience research

(2013) Rena Li et al.   LIFE SCIENCES

Erratum: Corrigendum: Global quantification of mammalian gene expression control

(2013) Björn Schwanhäusser et al.   NATURE

Molecular architecture of the chick vestibular hair bundle

(2013) Jung-Bum Shin et al.   NATURE NEUROSCIENCE

Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation

(2013) Ulrich M. Zanger et al.   PHARMACOLOGY & THERAPEUTICS

Nuclear receptors in the multidrug resistance through the regulation of drug-metabolizing enzymes and drug transporters

(2012) Yakun Chen et al.   BIOCHEMICAL PHARMACOLOGY

The Emerging Role of Human Esterases

(2012) Tatsuki Fukami et al.   Drug Metabolism and Pharmacokinetics

Choosing a stable housekeeping gene and protein is essential in generating valid gene and protein expression results

(2011) M Sullivan-Gunn et al.   BRITISH JOURNAL OF CANCER

Global quantification of mammalian gene expression control

(2011) Björn Schwanhäusser et al.   NATURE

Sex Differences in UDP-Glucuronosyltransferase 2B17 Expression and Activity

(2010) C. J. Gallagher et al.   DRUG METABOLISM AND DISPOSITION

Simultaneous Absolute Quantification of 11 Cytochrome P450 Isoforms in Human Liver Microsomes by Liquid Chromatography Tandem Mass Spectrometry with In Silico Target Peptide Selection

(2010) Hirotaka Kawakami et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Expression of common housekeeping genes is affected by disease in human hepatitis C virus-infected liver

(2010) Mario Congiu et al.   LIVER INTERNATIONAL

Role of Human Liver Microsomes in In Vitro Metabolism of Drugs—A Review

(2009) Sepuri Asha et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

The APEX Quantitative Proteomics Tool: Generating protein quantitation estimates from LC-MS/MS proteomics results

(2008) John C Braisted et al.   BMC BIOINFORMATICS

Absolute SILAC for Accurate Quantitation of Proteins in Complex Mixtures Down to the Attomole Level

(2008) Stefan Hanke et al.   JOURNAL OF PROTEOME RESEARCH