Naïve human pluripotent stem cells respond to Wnt, Nodal and LIF signalling to produce expandable naïve extra-embryonic endoderm

Transcriptional Heterogeneity in Naive and Primed Human Pluripotent Stem Cells at Single-Cell Resolution

(2019) Tobias Messmer et al.   Cell Reports

A single-cell molecular map of mouse gastrulation and early organogenesis

(2019) Blanca Pijuan-Sala et al.   NATURE

Human Pluripotency Is Initiated and Preserved by a Unique Subset of Founder Cells

(2019) Mio Nakanishi et al.   CELL

Molecular recording of mammalian embryogenesis

(2019) Michelle M. Chan et al.   NATURE

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

The endoderm: a divergent cell lineage with many commonalities

(2019) Sonja Nowotschin et al.   DEVELOPMENT

Molecular architecture of lineage allocation and tissue organization in early mouse embryo

(2019) Guangdun Peng et al.   NATURE

Single-Cell RNA-Seq Reveals Dynamic Early Embryonic-like Programs during Chemical Reprogramming

(2018) Ting Zhao et al.   Cell Stem Cell

Correction: Integrated analysis of single-cell embryo data yields a unified transcriptome signature for the human pre-implantation epiblast (doi: 10.1242/dev.158501)

(2018) Giuliano G. Stirparo et al.   DEVELOPMENT

Genetic Control of Early Cell Lineages in the Mammalian Embryo

(2018) Janet Rossant   Annual Review of Genetics

Single cell transcriptome analysis of human, marmoset and mouse embryos reveals common and divergent features of preimplantation development

(2018) Thorsten Boroviak et al.   DEVELOPMENT

Insulin fine-tunes self-renewal pathways governing naive pluripotency and extra-embryonic endoderm

(2017) Kathryn G. V. Anderson et al.   NATURE CELL BIOLOGY

Efficient Generation of Glucose-Responsive Beta Cells from Isolated GP2 + Human Pancreatic Progenitors

(2017) Jacqueline Ameri et al.   Cell Reports

Single-cell transcriptome of early embryos and cultured embryonic stem cells of cynomolgus monkeys

(2017) Tomonori Nakamura et al.   Scientific Data

MultiQC: summarize analysis results for multiple tools and samples in a single report

(2016) Philip Ewels et al.   BIOINFORMATICS

Single-Cell RNA-Seq Reveals Lineage and X Chromosome Dynamics in Human Preimplantation Embryos

(2016) Sophie Petropoulos et al.   CELL

A developmental coordinate of pluripotency among mice, monkeys and humans

(2016) Tomonori Nakamura et al.   NATURE

Embryonic Stem Cell Culture Conditions Support Distinct States Associated with Different Developmental Stages and Potency

(2016) Javier Martin Gonzalez et al.   Stem Cell Reports

OSKM Induce Extraembryonic Endoderm Stem Cells in Parallel to Induced Pluripotent Stem Cells

(2016) Anthony Parenti et al.   Stem Cell Reports

Naive Pluripotent Stem Cells Derived Directly from Isolated Cells of the Human Inner Cell Mass

(2016) Ge Guo et al.   Stem Cell Reports

Resetting Transcription Factor Control Circuitry toward Ground-State Pluripotency in Human

(2015) Yasuhiro Takashima et al.   CELL

LIF supports primitive endoderm expansion during pre-implantation development

(2015) Sophie M. Morgani et al.   DEVELOPMENT

Defining the three cell lineages of the human blastocyst by single-cell RNA-seq

(2015) P. Blakeley et al.   DEVELOPMENT

Gata6 potently initiates reprograming of pluripotent and differentiated cells to extraembryonic endoderm stem cells

(2015) Sissy E. Wamaitha et al.   GENES & DEVELOPMENT

ExAtlas: An interactive online tool for meta-analysis of gene expression data

(2015) Alexei A. Sharov et al.   Journal of Bioinformatics and Computational Biology

Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency

(2014) Thorold W. Theunissen et al.   Cell Stem Cell

GATA6 Levels Modulate Primitive Endoderm Cell Fate Choice and Timing in the Mouse Blastocyst

(2014) Nadine Schrode et al.   DEVELOPMENTAL CELL

Derivation of naive human embryonic stem cells

(2014) C. B. Ware et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Erk Signaling Suppresses Embryonic Stem Cell Self-Renewal to Specify Endoderm

(2014) William B. Hamilton et al.   Cell Reports

Induction of a Human Pluripotent State with Distinct Regulatory Circuitry that Resembles Preimplantation Epiblast

(2013) Yun-Shen Chan et al.   Cell Stem Cell

Atypical protein kinase C couples cell sorting with primitive endoderm maturation in the mouse blastocyst

(2013) N. Saiz et al.   DEVELOPMENT

Derivation of novel human ground state naive pluripotent stem cells

(2013) Ohad Gafni et al.   NATURE

Derivation of extraembryonic endoderm stem (XEN) cells from mouse embryos and embryonic stem cells

(2013) Kathy K Niakan et al.   Nature Protocols

Single-cell RNA-Seq profiling of human preimplantation embryos and embryonic stem cells

(2013) Liying Yan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Self-Renewing Endodermal Progenitor Lines Generated from Human Pluripotent Stem Cells

(2012) Xin Cheng et al.   Cell Stem Cell

The roles of FGF and MAP kinase signaling in the segregation of the epiblast and hypoblast cell lineages in bovine and human embryos

(2012) E. W. Kuijk et al.   DEVELOPMENT

Pluripotency in the Embryo and in Culture

(2012) J. Nichols et al.   Cold Spring Harbor Perspectives in Biology

BMP signaling induces visceral endoderm differentiation of XEN cells and parietal endoderm

(2011) Agnieszka Paca et al.   DEVELOPMENTAL BIOLOGY

BMP4 signaling directs primitive endoderm-derived XEN cells to an extraembryonic visceral endoderm identity

(2011) Jérôme Artus et al.   DEVELOPMENTAL BIOLOGY

Human hypoblast formation is not dependent on FGF signalling

(2011) Mila Roode et al.   DEVELOPMENTAL BIOLOGY

“Click” Conjugation of Peptide on the Surface of Polymeric Nanoparticles for Targeting Tumor Angiogenesis

(2011) Stéphanie Deshayes et al.   PHARMACEUTICAL RESEARCH

Protein Kinase C Mediated Extraembryonic Endoderm Differentiation of Human Embryonic Stem Cells

(2011) Xuezhu Feng et al.   STEM CELLS

A role for PDGF signaling in expansion of the extra-embryonic endoderm lineage of the mouse blastocyst

(2010) J. Artus et al.   DEVELOPMENT

FGF signal-dependent segregation of primitive endoderm and epiblast in the mouse blastocyst

(2010) Y. Yamanaka et al.   DEVELOPMENT

Functional Heterogeneity of Embryonic Stem Cells Revealed through Translational Amplification of an Early Endodermal Transcript

(2010) Maurice A. Canham et al.   PLOS BIOLOGY

Naive and Primed Pluripotent States

(2009) Jennifer Nichols et al.   Cell Stem Cell

The transcriptional foundation of pluripotency

(2009) I. Chambers et al.   DEVELOPMENT

Anterior Definitive Endoderm from ESCs Reveals a Role for FGF Signaling

(2008) Gillian M. Morrison et al.   Cell Stem Cell

Establishment of Endoderm Progenitors by SOX Transcription Factor Expression in Human Embryonic Stem Cells

(2008) Cheryle A. Séguin et al.   Cell Stem Cell

The Endoderm of the Mouse Embryo Arises by Dynamic Widespread Intercalation of Embryonic and Extraembryonic Lineages

(2008) Gloria S. Kwon et al.   DEVELOPMENTAL CELL

The ground state of embryonic stem cell self-renewal

(2008) Qi-Long Ying et al.   NATURE

Dynamic expression of Lrp2 pathway members reveals progressive epithelial differentiation of primitive endoderm in mouse blastocyst

(2007) François Gerbe et al.   DEVELOPMENTAL BIOLOGY