Journal
CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS
Volume 19, Issue 11, Pages -Publisher
SPRINGER
DOI: 10.1007/s11910-019-1000-5
Keywords
Multiple sclerosis; African-Americans; Progression; Disease severity
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Purpose of Review Multiple sclerosis (MS) is an autoimmune disease of the central nervous system that affects nearly 1 million people in the USA and has the potential to profoundly affect physical ability and income potential at a young age. Since a landmark paper was published in 2014, few studies have looked at differences in MS disease characteristics between African-American and Caucasian patients. Recent Findings African-American patients often have a more severe MS disease course, as well as biomarker data which can portend a worse prognosis. While the sample sizes are usually quite small, subgroup analyses of African-American patients have been performed to evaluate efficacy of disease-modifying treatments as compared with the entire study population, made up of primarily Caucasians. Summary In an era where we strive for personalized medicine, understanding racial differences in MS may help us better treat African-American patients in the future.
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