Review
Biochemistry & Molecular Biology
Christina Kannigadu, David. D. N'Da
Summary: Curcumin, a natural compound, has been used in traditional Asian medicine for centuries and shows promising biological and pharmacological activities. Despite being investigated for its potential in treating various diseases, including infectious ones, curcumin is still in clinical trials. Recent research focuses on the discovery, synthesis, mechanisms of action, and pharmacological effects of curcumin and its derivatives as potential agents for infectious disease treatment.
CURRENT MEDICINAL CHEMISTRY
(2021)
Review
Infectious Diseases
Firzan Nainu, Ayu Masyita, Muh. Akbar Bahar, Muhammad Raihan, Shajuthi Rahman Prova, Saikat Mitra, Talha Bin Emran, Jesus Simal-Gandara
Summary: Bee products have been traditionally used for treating various disorders, including cancer and microbial-related diseases. Compounds found in bee products show potential in anticancer, antibacterial, antiviral, and antiparasitic activity, making them promising for cancer and infectious disease management.
Review
Chemistry, Inorganic & Nuclear
Claudio Pettinari, Riccardo Pettinari, Corrado Di Nicola, Alessia Tombesi, Stefania Scuri, Fabio Marchetti
Summary: This article discusses the recent advances in antimicrobial MOFs, covering various aspects of their biomedical applications. It outlines the potential offered by MOFs and composite materials containing MOFs in the field of antimicrobial materials, along with describing the key parameters in the design and production of antimicrobial MOFs.
COORDINATION CHEMISTRY REVIEWS
(2021)
Review
Chemistry, Medicinal
Jimin Xu, Yu Xue, Andrew A. Bolinger, Jun Li, Mingxiang Zhou, Haiying Chen, Hongmin Li, Jia Zhou
Summary: Since ancient times, human beings have been fighting against viral infections. The ongoing coronavirus disease 2019 pandemic is one of the most severe public health emergencies in human history, emphasizing the urgent need for broad-spectrum antiviral agents. Salicylamide derivatives, such as niclosamide and nitazoxanide, have shown inhibitory effects against a wide range of RNA and DNA viruses, including flavivirus, influenza A virus, and coronavirus. Clinical trials have demonstrated the effectiveness of nitazoxanide against various viral infections, such as rotavirus and norovirus-induced diarrhea, uncomplicated influenza A and B, hepatitis B, and hepatitis C. This review summarizes the broad antiviral activities of salicylamide derivatives, their clinical progress, potential targets or mechanisms against different viral infections, and highlights their therapeutic potential in combating current and emerging viral infections.
MEDICINAL RESEARCH REVIEWS
(2023)
Review
Food Science & Technology
Felix Zulhendri, Kavita Chandrasekaran, Magdalena Kowacz, Munir Ravalia, Krishna Kripal, James Fearnley, Conrad O. Perera
Summary: Propolis is a complex phytocompound with antiviral, antibacterial, antifungal, and antiparasitic properties. It acts by disrupting the pathogens' ability to invade host cells and inhibiting their replication and metabolic processes. Additionally, propolis functions as an immunomodulator, upregulating innate immunity and maintaining cellular antioxidant status.
Review
Biology
Nelly Rivera-Yanez, C. Rebeca Rivera-Yanez, Glustein Pozo-Molina, Claudia F. Mendez-Catala, Julia Reyes-Reali, Maria I. Mendoza-Ramos, Adolfo R. Mendez-Cruz, Oscar Nieto-Yanez
Summary: Propolis, a beekeeping product with a complex chemical composition, has shown promising effects in treating infectious diseases. However, challenges remain in assessing its effects in clinical studies for safe and effective use.
Review
Agriculture, Multidisciplinary
Fazlurrahman Khan, Nazia Tabassum, Nilushi Indika Bamunuarachchi, Young-Mog Kim
Summary: Phloroglucinol and its derivatives have been widely used to treat microbial infections and exhibit diverse biological activities. With the increasing resistance of microorganisms to antimicrobial drugs, the synthesis of more phloroglucinol derivatives is crucial to meet the growing demand. This review provides an overview of the application of phloroglucinol and its derivatives in antibacterial action and explores their potential future perspectives.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2022)
Review
Biochemistry & Molecular Biology
Meijie Xu, Ziwei Huang, Wangjie Zhu, Yuanyuan Liu, Xuelian Bai, Huawei Zhang
Summary: Fungal microbes, particularly Fusarium spp., have been identified as a prolific source of secondary metabolites (SMs) with diverse chemical structures and broad-spectrum antimicrobial properties. A thorough literature search and data analysis revealed the discovery of 185 antimicrobial natural products derived from Fusarium strains by the end of 2022. These substances exhibit various antimicrobial effects, including antibacterial, antifungal, antiviral, and antiparasitic activities. Furthermore, suggestions for future research on efficient discovery of novel bioactive SMs from Fusarium strains are proposed.
Review
Pharmacology & Pharmacy
Xinwei Zhang, Si Chen, Xue Li, Liying Zhang, Linzhu Ren
Summary: Flavonoids are natural substances with phenolic structures that have antioxidant, anti-inflammatory, anticancer, and antiviral activities. This review summarizes the recent progress in understanding the antiviral mechanisms of flavonoids against porcine viruses, highlighting their potential for controlling porcine virus infection and developing pig feed additives.
Review
Biochemistry & Molecular Biology
Zihao Zhu, Shujuan Zhao, Changhong Wang
Summary: This paper reviews the antibacterial, antifungal, antiviral, and antiparasitic activities of Peganum harmala, aiming to contribute to research on medicinal applications of P. harmala and provide a reference in the field of antimicrobial while also providing a basis for the development of natural antimicrobial agents for the treatment of infectious diseases.
Article
Biochemistry & Molecular Biology
Gustavo Souza dos Santos, Maria Valdeline Sousa Teixeira, Leandro da Costa Clementino, Pericles Abreu Gama-Filho, Luiz Miguel Pereira, Thaiz Rodrigues Teixeira, Niege Aracari Jacometti Cardoso Furtado, Marcia Aparecida da Silva Graminha, Ana Patricia Yatsuda, Pio Colepicolo Neto, Ru Angelie Edrada-Ebel, Hosana Maria Debonsi
Summary: In this study, bioactive compounds of Phaeurus antarcticus were investigated using GC-MS analysis and multivariate analysis. The results showed that P. antarcticus exhibited antibacterial and antiparasitic activities, possibly through interactions with Heme proteins.
CHEMISTRY & BIODIVERSITY
(2023)
Article
Multidisciplinary Sciences
Peipei Cui, Mingjiang Cai, Yanan Meng, Yan Yang, Hongjian Song, Yuxiu Liu, Qingmin Wang
Summary: In this study, a series of echinopsine derivatives containing acylhydrazone moieties were designed, synthesized, and evaluated for their biological activities. The compounds showed good antiviral activity against tobacco mosaic virus, as well as insecticidal and fungicidal activities.
SCIENTIFIC REPORTS
(2022)
Review
Polymer Science
Md Abdul Wahab, Li Luming, Md Abdul Matin, Mohammad Rezaul Karim, Mohammad Omer Aijaz, Hamad Fahad Alharbi, Ahmed Abdala, Rezwanul Haque
Summary: Silver has become a potent agent for effective antibacterial applications in nanostructured materials. Silver nanoparticles play a major role in various industries and are prepared using methods that reduce toxicity. Basic structural parameters like size, shape, and chemical composition significantly impact the antimicrobial activities, highlighting the importance of designing appropriate formulations.
Review
Pharmacology & Pharmacy
Ying-Qi Wu, Tong Tong
Summary: Curcumae Rhizoma, the dried rhizome of Curcuma longa L., is widely grown in tropical south and southwest Asia. It has been used to treat dermatoses, infections, stress, and depression. In China, it has been made into pharmaceutical preparations with proven antioxidant, anti-inflammatory, and anti-cancer effects. It has shown potential in treating various diseases, including cancer, infectious-, autoimmune-, neurological-, and cardiovascular diseases, as well as diabetes. Additionally, it has been researched for its anti-infective effects against COVID-19, influenza virus, hepatitis B virus, human immunodeficiency virus, and human papilloma virus.
FRONTIERS IN PHARMACOLOGY
(2023)
Review
Chemistry, Multidisciplinary
Johana Zuniga-Miranda, Julio Guerra, Alexander Mueller, Arianna Mayorga-Ramos, Saskya E. Carrera-Pacheco, Carlos Barba-Ostria, Jorge Heredia-Moya, Linda P. Guaman
Summary: The inappropriate use of antimicrobial agents has led to the rise of antimicrobial resistance, posing a global health threat. Nanotechnology provides a potential solution through the synthesis of nanoparticles with antimicrobial activity, such as iron oxide nanoparticles. This review highlights key findings in the green synthesis of iron oxide nanoparticles using bacteria, fungi, plants, and organic waste, discusses challenges encountered in green synthesis with diverse organisms and materials, and explores the applications of these nanoparticles as promising antibacterial, antifungal, antiparasitic, and antiviral agents.
Article
Chemistry, Physical
Greta G. Zambo, Jonas F. Schlagintweit, Robert M. Reich, Fritz E. Kuehn
Summary: The development of selective oxidation processes for hydrocarbons is an important area of research in catalysis. Making these processes environmentally friendly is a challenge. N-heterocyclic carbenes (NHCs) have attracted attention for their ability to stabilize transition metals in high oxidation states, which are key intermediates in oxidation catalysis. This review summarizes recent applications of 3d transition metal NHC complexes in oxidation catalysis and highlights advances in catalytic oxidation of important substrates such as alkenes, alkanes, aromatics, alcohols, and amines until the end of 2021. It also discusses the activation of molecular oxygen using first row transition metal NHC complexes as a green and abundant oxidant.
CATALYSIS SCIENCE & TECHNOLOGY
(2022)
Review
Radiology, Nuclear Medicine & Medical Imaging
Maria Cristina Oliveira, Joao D. G. Correia
Summary: Despite our increased understanding of the molecular basis of carcinogenesis, the eradication of cancer remains difficult due to factors such as molecular heterogeneity and late-stage diagnosis. Radioimmunotherapy (RIT), which combines specific antibodies with therapeutic radionuclides, offers a potential solution by delivering high doses of radiation to cancer cells while sparing normal cells.
CLINICAL AND TRANSLATIONAL IMAGING
(2022)
Article
Chemistry, Multidisciplinary
Yangming Ding, Tenglong Guo, Zhewei Li, Bo Zhang, Fritz E. Kuhn, Chang Liu, Jian Zhang, Dezhu Xu, Ming Lei, Tao Zhang, Changzhi Li
Summary: A one-pot cascade reaction was developed for the synthesis of quinoline from beta-O-4 model compounds, achieving high yields. The reaction pathway involves selective cleavage of C-O bonds, dehydrogenation, aldol condensation, and C-N bond formation.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Multidisciplinary Sciences
Bo Zhang, Tenglong Guo, Zhewei Li, Fritz E. Kuhn, Ming Lei, Zongbao K. Zhao, Jianliang Xiao, Jian Zhang, Dezhu Xu, Tao Zhang, Changzhi Li
Summary: This study reports a novel method for synthesizing heterocyclic aromatic compounds from lignin, which is of great importance for expanding the product portfolio derived from biomass. The method is transition-metal free and sustainable, making it applicable for pharmaceutical synthesis.
NATURE COMMUNICATIONS
(2022)
Article
Chemistry, Inorganic & Nuclear
Mohammad Kaikhosravi, Alexander D. Boeth, Michael J. Sauer, Robert M. Reich, Fritz E. Kuehn
Summary: The heterobimetallic N-heterocyclic dicarbene (NHDC) rhodium ruthenium complex was synthesized via transmetallation and tested as a catalyst in the transfer hydrogenation reaction of acetophenone. The complex exhibited high turnover frequency and good catalytic performance.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2022)
Editorial Material
Chemistry, Applied
Bo Zhang, Fritz E. Kuehn
JOURNAL OF ENERGY CHEMISTRY
(2023)
Article
Multidisciplinary Sciences
Ana S. Andre, Joana N. R. Dias, Sandra Aguiar, Sara Nogueira, Pedro Bule, Joana Ines Carvalho, Joao P. M. Antonio, Marco Cavaco, Vera Neves, Soraia Oliveira, Goncalo Vicente, Belmira Carrapico, Berta Sao Braz, Barbara Ruetgen, Lurdes Gano, Joao D. G. Correia, Miguel Castanho, Joao Goncalves, Pedro M. P. Gois, Solange Gil, Luis Tavares, Frederico Aires-da-Silva
Summary: Antibody-drug conjugates (ADCs) are a rapidly growing therapeutic class in oncology, but they face significant engineering challenges. To develop more stable and effective ADCs, researchers explored the potential of rabbit-derived VL-single-domain antibody scaffolds (sdAbs) to selectively conjugate a payload to Cys80.
SCIENTIFIC REPORTS
(2023)
Article
Chemistry, Physical
Tim P. Schlachta, Greta G. Zambo, Michael J. Sauer, Isabelle Rueter, Carla A. Hoefer, Serhiy Demeshko, Franc Meyer, Fritz E. Kuehn
Summary: A comparative study was conducted to investigate the influence of electronic variations on the catalytic performance of three iron(II) NHC epoxidation catalysts. Different ligands were used to prepare the complexes, which were characterized using various methods. The results showed that a lower electron density at the iron atom led to a decline in epoxidation activity, while a more electron rich iron center did not necessarily result in higher activity due to reduced catalyst stability. Addition of Lewis acids significantly improved both activity and stability of the catalysts.
JOURNAL OF CATALYSIS
(2023)
Review
Chemistry, Multidisciplinary
Tim P. P. Schlachta, Fritz E. E. Kuehn
Summary: Cyclic iron tetracarbenes are a class of macrocyclic iron N-heterocyclic carbene (NHC) complexes, inspired by heme analogs but with different electronic properties. The modification of their ligand framework allows control over the structural and electronic properties of the complexes. These iron tetracarbene complexes exhibit unique reactivity, involving the isolation of uncommon iron(iii) and iron(iv) species. They have been successfully applied in various catalytic reactions, such as C-H activation, CO2 reduction, aziridination, and epoxidation. This review provides insights for researchers to evaluate the properties of their complexes and optimize catalyst properties through ligand design.
CHEMICAL SOCIETY REVIEWS
(2023)
Article
Chemistry, Inorganic & Nuclear
Leon F. Richter, Fernanda Marques, Joao D. G. Correia, Alexander Poethig, Fritz E. Kuehn
Summary: The synthesis of a homoleptic azide-functionalised Au(I) bis-1,2,3-triazole-5-ylidene complex is reported, demonstrating the efficient modification ability and steric shielding superiority of the presented triazole ligand framework in click-chemistry protocols. The complex exhibits high antiproliferative activity in A2780 and MCF-7 human cancer cells.
DALTON TRANSACTIONS
(2023)
Meeting Abstract
Biochemistry & Molecular Biology
Marco Cavaco, Javier Velle, Ruben D. M. Silva, Joao D. G. Correia, Miguel A. R. B. Castanho, David Andreu, Vera Neves
JOURNAL OF PEPTIDE SCIENCE
(2022)
Meeting Abstract
Biochemistry & Molecular Biology
Ana Salome Veiga, Iris Cadima-Couto, Alexandra Tauzin, Joao M. Freire, Tiago N. Figueira, Ruben D. M. Silva, Clara Perez-Peinado, Catarina Cunha-Santos, Ines Bartolo, Nuno Taveira, Lurdes Gano, Joao D. G. Correia, Joao Goncalves, Fabrizio Mammano, David Andreu, Miguel A. R. B. Castanho
JOURNAL OF PEPTIDE SCIENCE
(2022)
Article
Chemistry, Inorganic & Nuclear
Greta G. Zambo, Johannes Mayr, Michael J. Sauer, Tim P. Schlachta, Robert M. Reich, Fritz E. Kuehn
Summary: The synthesis and characterization of a novel macrocyclic and abnormally coordinating, mesoionic N-heterocyclic carbene iron complex are reported. The complex exhibits strong sigma-donor ability of the carbene moieties, indicating efficient catalytic activity in oxidation reactions. Initial tests on the epoxidation of cis-cyclooctene validate the assumption.
DALTON TRANSACTIONS
(2022)
Article
Chemistry, Physical
Alexander D. Boeth, Michael J. Sauer, Walter Baratta, Fritz E. Kuehn
Summary: The bis-abnormal N-heterocyclic carbene (aNHC) ruthenium complexes showed high catalytic activity in transfer hydrogenation and Oppenauer-type oxidation reactions. The order of reactivity was found to be influenced by steric effects.
CATALYSIS SCIENCE & TECHNOLOGY
(2022)
Article
Virology
Francesca Caccuri, Vera Neves, Lurdes Gano, Joao D. G. Correia, Maria Cristina Oliveira, Pietro Mazzuca, Arnaldo Caruso, Miguel Castanho
Summary: Human immunodeficiency virus type 1 (HIV-1)-associated neurocognitive disorder (HAND) is a significant neurological manifestation in HIV-1-infected patients. This study demonstrates the ability of the HIV-1 matrix protein p17 to cross the blood-brain barrier (BBB) and reach the central nervous system (CNS), supporting its direct role in neuronal dysfunction in HAND.
JOURNAL OF VIROLOGY
(2022)
Review
Chemistry, Inorganic & Nuclear
Pegah Hajivand, Johannes Carolus Jansen, Emilio Pardo, Donatella Armentano, Teresa F. Mastropietro, Amirreza Azadmehr
Summary: VOCs in human breath can be used as biomarkers for diseases, and MOFs have been extensively studied as gas sensors for VOCs. This review provides a comprehensive summary of the latest MOF-derived composites used as VOCs biomarkers' sensors, and discusses the structural and functional characteristics of MOFs, sensing properties, and the potential of bio-MOFs in VOCs sensing.
COORDINATION CHEMISTRY REVIEWS
(2024)
Review
Chemistry, Inorganic & Nuclear
Seoyoon Song, Deborah Lee, Lucia C. Dalle Ore, Sungjun Kwak, Lifeng Kang, Hyung Kyo Kim, Noah Malmstadt, Sun Min Kim, Tae-Joon Jeon
Summary: This paper introduces the latest advancements in photoactivable liposomes in drug delivery, highlighting their advantages in precise control over drug release and targeted delivery, as well as the fine control over release kinetics achieved through the manipulation of light-responsive components. Additionally, the paper emphasizes the design considerations of physicochemical properties and light-related constituents.
COORDINATION CHEMISTRY REVIEWS
(2024)
Review
Chemistry, Inorganic & Nuclear
Shudi Liu, Liangwei Zhang, Heejeong Kim, Jinyu Sun, Juyoung Yoon
Summary: Chromium is a strategic and critical transition metal element with extensive applications. Efficient detection methods, such as fluorescence and colorimetry, have been developed for monitoring its concentrations. However, existing reviews on fluorescent probes for chromium lack comprehensive coverage. This review aims to consolidate information and promote the development of novel fluorescent probes for chromium detection.
COORDINATION CHEMISTRY REVIEWS
(2024)
Review
Chemistry, Inorganic & Nuclear
Rehab H. Elattar, Samah F. El-Malla, Amira H. Kamal, Fotouh R. Mansour
Summary: Metal complexes have strong analysis potential and can be used to measure analytes lacking essential chemical properties. Their analytical methods based on different mechanisms offer superior performance.
COORDINATION CHEMISTRY REVIEWS
(2024)
Review
Chemistry, Inorganic & Nuclear
Nem Singh, Miae Won, Yunjie Xu, Changyu Yoon, Jiyoung Yoo, Mingle Li, Heemin Kang, Jong Seung Kim
Summary: Hypoxia is a common occurrence in the tumor microenvironment and poses challenges for cancer treatment. The introduction of covalent organic frameworks (COFs) offers promising prospects for addressing hypoxia-related issues. This article explores the role of COFs in enhancing oxygen delivery, generating reactive oxygen species, optimizing drug delivery, and enabling hypoxia-specific imaging, as well as outlining their applications in various hypoxia-targeting therapeutic modalities.
COORDINATION CHEMISTRY REVIEWS
(2024)
Review
Chemistry, Inorganic & Nuclear
Priyadarshi Roy Chowdhury, Himani Medhi, Krishna G. Bhattacharyya, Chaudhery Mustansar Hussain
Summary: This review critically analyzes the production of waste-derived layered double hydroxides (LDH) and their utility in electrochemical water splitting for the generation of green hydrogen as sustainable energy. It highlights the importance of waste-derived LDH and discusses the challenges and future directions in this field.
COORDINATION CHEMISTRY REVIEWS
(2024)
Review
Chemistry, Inorganic & Nuclear
Rajamanickam Sivakumar, Nae Yoon Lee
Summary: This article reviews the progress in imaging reactive oxygen, nitrogen, and sulfur species (RONSS) using luminescent metal complex-based probes. This technology is selective and sensitive, which is of great significance for studying the impact of RONSS in cells and tissues and preventing diseases.
COORDINATION CHEMISTRY REVIEWS
(2024)
Review
Chemistry, Inorganic & Nuclear
Xinyang Li, Binbin Ding, Pan Zheng, Ping'an Ma, Jun Lin
Summary: The main goal of immunotherapy is to enhance the response and cytotoxicity of tumor-specific T cells by turning cold tumors into hot tumors. However, metabolic reprogramming in the tumor microenvironment can depress the cytotoxicity of T cells and hinder the effectiveness of immunotherapy. This review discusses the role of metabolic reprogramming in the interplay between cancer cells and immune cells in the tumor microenvironment and explores the use of nanomaterials to modulate metabolic pathways and improve immunotherapy outcomes.
COORDINATION CHEMISTRY REVIEWS
(2024)
Review
Chemistry, Inorganic & Nuclear
Kingsley Poon, Abhishek Gupta, William S. Price, Hala Zreiqat, Gurvinder Singh
Summary: Progress in the development of manganese oxide nanoparticles (MONPs) has provided an alternative for early-stage diagnosis of life-threatening diseases and therapeutic delivery of drugs and genes. The synthesis and characterization of MONPs have enabled the production of multi-functional targeted nanoparticles in various sizes and shapes. The integration of diagnosis and therapeutic capabilities within a single entity, known as nanotheranostics, is promising for real-time monitoring of disease progression and evaluating therapeutic treatment efficacy.
COORDINATION CHEMISTRY REVIEWS
(2024)
Review
Chemistry, Inorganic & Nuclear
Reza Abedi-Firoozjah, Hadiseh Ebdali, Mahya Soltani, Parastoo Abdolahi-Fard, Mahshid Heydari, Elham Assadpour, Maryam Azizi-Lalabadi, Fuyuan Zhang, Seid Mahdi Jafari
Summary: With the increasing awareness of food safety, there is a growing demand for efficient and affordable sensing methods for the detection of pathogens and toxins in food products. Nanosensors offer promising solutions with their quick and reliable detection capabilities, although challenges remain in their fabrication and practical application.
COORDINATION CHEMISTRY REVIEWS
(2024)
Review
Chemistry, Inorganic & Nuclear
Demei Sun, Xuesong Feng, Xinyuan Zhu, Youfu Wang, Jinghui Yang
Summary: Metal organic cages (MOCs) with precise and tunable nano structures show great potential in cancer therapy. Their diverse functions and ultrasmall size make them excellent nanoagents for different anticancer strategies, demonstrating outstanding anticancer performances.
COORDINATION CHEMISTRY REVIEWS
(2024)
Review
Chemistry, Inorganic & Nuclear
Li Li, Yang-Tao Yu, Ning-Ning Zhang, Shu-Hao Li, Jian-Ge Zeng, Yang Hua, Hong Zhang
Summary: This article summarizes recent advances in POM-based hybrid photochromic materials (PCHPMs), including structure types, new photochromic mechanisms, and applications. It can provide valuable guidance for researchers investigating POM-based hybrid photochromic materials.
COORDINATION CHEMISTRY REVIEWS
(2024)
Review
Chemistry, Inorganic & Nuclear
Chien Ing Yeo, Clariss Hui Peng Goh, Edward R. T. Tiekink, Jactty Chew
Summary: This review article provides an overview of the antibacterial activity of gold complexes, with a focus on gold(I) and gold(III) complexes. It also summarizes the repurposing of Auranofin for antibacterial purposes and the associated mechanism(s) of action.
COORDINATION CHEMISTRY REVIEWS
(2024)
Review
Chemistry, Inorganic & Nuclear
Sangharaj Diyali, Nilankar Diyali, Bhaskar Biswas
Summary: This study discusses the recent progress in the design and development of catalysts, focusing on the factors influencing overpotential, catalytic rate, and stability, as well as the mechanisms of the hydrogen evolution reaction in acidic and alkaline media. Moreover, it outlines the challenges in future design of robust and active electrocatalysts.
COORDINATION CHEMISTRY REVIEWS
(2024)
Review
Chemistry, Inorganic & Nuclear
Shaik Gouse Peera, Rahul S. Menon, Sumanta Kumar Das, Akram Alfantazi, K. Karuppasamy, Chao Liu, Akhila Kumar Sahu
Summary: Doped carbon materials, especially F-doped carbon catalysts, have gained significant attention as metal-free catalysts for oxygen reduction reactions and as corrosion-resistant supports for Pt and non-Pt nanoparticles. F-doped carbon materials possess unique properties and greatly improve the activity and durability of the ORR compared to N-doped carbon materials. The high electronegativity of F-doping can efficiently modify the electronic band structure of carbon materials, favoring the ORR. This review systematically discusses the effect of F-doping/F co-doping on the electrocatalytic reduction of O2 in acidic and alkaline conditions, the stability and durability of fuel cell catalysts, and provides guidelines for working with F-doped carbons. Future research directions on F-doped carbons are also proposed to bridge the gap between laboratory-scale assessments and commercial applications.
COORDINATION CHEMISTRY REVIEWS
(2024)
