Article
Environmental Sciences
Kumari Vandana Singh, Rakesh Arya, Jay Prakash Nirala, Debasis Sahu, Ranjan Kumar Nanda, Paulraj Rajamani
Summary: This study reveals the deregulation of hippocampus proteome upon exposure to mobile phone radiation, which may influence the healthy functioning of the brain.
ENVIRONMENTAL TOXICOLOGY
(2022)
Review
Health Care Sciences & Services
Xinxi Cao, Yangyang Cheng, Chenjie Xu, Yabing Hou, Hongxi Yang, Shu Li, Ying Gao, Peng Jia, Yaogang Wang
Summary: Improper use of mobile phones increases the risk of accidents and chronic disorders. This study found that long-term use of mobile phones is associated with higher accident risk and various health issues such as neoplasms, eye diseases, mental health disorders, and headaches. Proper and reasonable use of mobile phones is essential for minimizing these risks.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2022)
Review
Endocrinology & Metabolism
Jun Hirayama, Atsuhiko Hattori, Akihisa Takahashi, Yukihiro Furusawa, Yoshiaki Tabuchi, Masahiro Shibata, Aiko Nagamatsu, Sachiko Yano, Yusuke Maruyama, Hajime Matsubara, Toshio Sekiguchi, Nobuo Suzuki
Summary: Exposure to the space environment has numerous adverse effects on astronauts, including bone loss, sleep disorders, circadian rhythm disruption, cardiovascular and metabolic dysfunction, and impaired immune function. Melatonin, a hormone regulating various physiological functions, appears to play a crucial role in mitigating these effects and protecting against space radiation.
JOURNAL OF PINEAL RESEARCH
(2023)
Article
Biology
Xuewei Fan, Zeqing Chen, Wenqi Li, Haokuan Qin, Shijie Huang, Zhicheng Lu, Yinghua Li, Muqing Liu
Summary: This study found that blue and red cutaneous exposure had no significant effect on central rhythm oscillation, while intraocular irradiation could significantly change the central clock of mice. The impact of blue light was stronger than red light, suggesting that intraocular nonvisual channels still play a dominant role in rhythmic regulation.
CHRONOBIOLOGY INTERNATIONAL
(2021)
Article
Health Care Sciences & Services
Hanneke Poort, Annelise Ryan, Katelyn MacDougall, Paige Malinowski, Anna MacDonald, Zach Markin, William Pirl, Joseph Greer, Karen Fasciano
Summary: The study aimed to evaluate the feasibility and acceptability of a smartphone app called iaya designed to create an engaged community for young adult patients to learn emotional coping skills. Results showed that although the app was deemed acceptable by patients, it did not meet the a priori feasibility criteria as a stand-alone intervention.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2021)
Review
Biochemistry & Molecular Biology
Ting Gao, Yixuan Li, Xiaoyu Wang, Fazheng Ren
Summary: Sunlight has adverse effects on the skin, including hyperpigmentation, collagen degradation, fibrosis, and even skin cancer. This article focuses on the negative impact of sunlight on the skin, not only in terms of photoaging but also its influence on the skin's circadian rhythm.
Article
Psychiatry
Hong Yang, Kun Yang, Lu Zhang, Ni Yang, Ying-Xiu Mei, Ya-Li Zheng, Yan He, Yan-Ju Gong, Wei-Jun Ding
Summary: This study aims to detect circadian rhythm disorders in patients with mobile phone addiction and investigate the effects of acupuncture. The results showed that acupuncture significantly alleviated sleep disorders and restored circadian rhythm.
FRONTIERS IN PSYCHIATRY
(2023)
Article
Endocrinology & Metabolism
Aurea S. Blancas-Velazquez, Tenna Bering, Signe Bille, Martin F. Rath
Summary: This study aims to investigate the role of clock genes on pineal gland endocrine function, particularly on the enzyme Aanat involved in melatonin synthesis. It was found that rhythmic clock gene expression in the pineal gland largely depends on the suprachiasmatic nucleus (SCN) and pineal cells house a slave oscillator controlled by adrenergic signaling. Histological analysis revealed that clock genes are expressed in pinealocytes and colocalize with Aanat transcripts, suggesting their involvement in cellular melatonin production. Knockdown of the clock gene Clock led to an overexpression of Aanat in pinealocytes, indicating that SCN-dependent rhythmic expression of Clock gene regulates the daily profile of Aanat expression.
JOURNAL OF PINEAL RESEARCH
(2023)
Article
Environmental Sciences
Ranjeet Kumar, Pravin S. Deshmukh, Sonal Sharma, Basu Dev Banerjee
Summary: This study evaluated the dose-dependent and frequency-dependent epigenetic modulation in the hippocampus of Wistar rats exposed to RF-MW at different frequencies and absorption rates for varying durations. The results showed significant alterations in global DNA and histone methylation in the hippocampus with increasing frequency and duration of microwave exposure, indicating a potential impact on gene expression.
ENVIRONMENTAL RESEARCH
(2021)
Article
Ergonomics
Beau Mostyn Sullivan, Amanda M. George, Patricia M. Brown
Summary: The study found that lower premeditation and higher positive urgency from impulsivity facets significantly predicted various MWD behaviors, while higher mobile phone involvement was a stronger predictor of MWD. There were significant indirect effects of positive and negative urgency on MWD behaviors through mobile phone involvement.
ACCIDENT ANALYSIS AND PREVENTION
(2021)
Article
Health Care Sciences & Services
Pelin Ozluk, Rebecca Cobb, Alyson Hoots, Malgorzata Sylwestrzak
Summary: This study evaluates the effectiveness of the mobile app ianacare in improving caregivers' support system, time use, productivity, and health and well-being. The results show that the app is associated with positive changes in various caregiver outcomes, such as increased assistance from personal support networks and reduced time off work for caregiving tasks.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2022)
Article
Multidisciplinary Sciences
Rui F. O. Silva, Brigida R. Pinho, Nuno M. Monteiro, Miguel M. Santos, Jorge M. A. Oliveira
Summary: Behavioral studies are crucial for understanding normal and disrupted biological mechanisms. The development of a versatile software called Rtivity allows researchers to analyze behavioral patterns, biological rhythms, stimulus responses, and survival in diverse animal species.
SCIENTIFIC REPORTS
(2022)
Review
Engineering, Electrical & Electronic
Reyhaneh Ayardulabi, Erfan Khamespanah, Sarv Abbasinia, Hamide Ehtesabi
Summary: Detection of specific cells and molecules in remote and resource-limited areas is challenging, leading to an increased demand for Point-Of-Care (POC) systems. Smartphones have emerged as a practical solution for this issue due to their image-capturing and processing capabilities. Smartphone-based microscopes have been utilized in medical diagnosis, food pathogen identification, and biomolecule detection, with or without external attachments. The studies discussed in the article are categorized based on the type of biological samples tested and platforms used for examination and quantification.
SENSORS AND ACTUATORS A-PHYSICAL
(2021)
Review
Pharmacology & Pharmacy
Shuhui Jia, Xuantong Guo, Zuxin Chen, Shupeng Li, Xin-an Liu
Summary: Given the devastating social and health consequences of drug addiction and the limitations of current treatments, a new strategy involving correcting abnormal circadian rhythms and improving sleep quality may be beneficial in the treatment of drug addiction. Melatonin, a circadian hormone with various neuroprotective and pharmacological effects, has shown potential as an intervention for substance use disorders. This review discusses the roles of melatonin at different levels and its potential applications in drug addiction.
PHARMACOLOGICAL RESEARCH
(2022)
Article
Biology
Imam Hasan, Tanjina Amin, Md. Rafiqul Alam, Mohammad Rafiqul Islam
Summary: The study found that exposure to fourth-generation cell phone radiation may affect blood hemostasis and inflammation of mice's kidney and testis tissue.
SAUDI JOURNAL OF BIOLOGICAL SCIENCES
(2021)
Article
Zoology
Sayaka Komada, Yuichi Kamae, Mitsumasa Koyanagi, Kousuke Tatewaki, Ehab Hassaneen, A. S. M. Saifullah, Taishi Yoshii, Akihisa Terakita, Kenji Tomioka
ZOOLOGICAL LETTERS
(2015)
Article
Biology
Mohamed A. Elsaey, Alaa El-Din Sallam, Ehab Hassaneen, Mohamad S. Zaghloul
BIOLOGICAL RHYTHM RESEARCH
(2016)
Article
Environmental Sciences
Elham M. Ali, Hanan M. Khairy
ENVIRONMENTAL POLLUTION
(2016)
Article
Biochemistry & Molecular Biology
Amira A. H. Ali, Federica Tundo-Lavalle, Soha A. Hassan, Martina Pfeffer, Anna Stahr, Charlotte von Gall
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2020)
Article
Oncology
Soha A. Hassan, Christian Schmithals, Maike von Harten, Albrecht Piiper, Horst-Werner Korf, Charlotte von Gall
Summary: The study demonstrated time-dependent changes in proliferation and DNA damage in HCC and HL, as well as time-of-day dependent expression of clock genes in ex vivo samples. These findings support the concept of chronotherapy for HCC and suggest OSC as a useful tool for testing novel cancer therapies.
INTERNATIONAL JOURNAL OF CANCER
(2021)
Article
Endocrinology & Metabolism
Soha A. Hassan, Amira A. H. Ali, Mona Yassine, Dennis Sohn, Martina Pfeffer, Reiner U. Jaenicke, Horst-Werner Korf, Charlotte von Gall
Summary: This study investigated the relationship between locomotor activity rhythm, corticosterone levels, hepatocellular carcinoma (HCC) development, and radiotherapy treatment in a mouse model, revealing that phenobarbital treatment may weaken corticosterone levels and destabilize activity rhythms, while tumors may cause increased corticosterone levels and decreased activity. Radiation therapy resulted in further elevation of corticosterone levels and disruption of activity rhythms, suggesting that early light phase might be the optimal time to apply radiotherapy to minimize side effects.
JOURNAL OF PINEAL RESEARCH
(2021)
Article
Biochemistry & Molecular Biology
Amira A. H. Ali, Laila Abdel-Hafiz, Federica Tundo-Lavalle, Soha A. Hassan, Charlotte von Gall
Summary: The P2Y(2) receptor plays a crucial role in the proliferation of neuronal precursor cells as well as in hippocampus-dependent working memory and olfactory function, as indicated by reduced NPC proliferation and impaired performance in working memory and olfactory tasks in P2Y2(-/-) mice.
Article
Oncology
Soha A. Hassan, Amira A. H. Ali, Dennis Sohn, Ulrich Floegel, Reiner U. Jaenicke, Horst-Werner Korf, Charlotte von Gall
Summary: This study found that irradiation at ZT20 is the optimal time point for treating hepatocellular carcinoma in mice, increasing treatment efficacy and reducing side effects on non-tumoral liver. Irradiation at other time points also affected clock gene expression, but the impact was minimal at ZT20.
Article
Cell Biology
Mona Yassine, Soha A. Hassan, Simon Sommer, Lea Aylin Yuecel, Hanna Bellert, Johanna Hallenberger, Dennis Sohn, Horst-Werner Korf, Charlotte von Gall, Amira A. H. Ali
Summary: Chronic liver diseases, including hepatocellular carcinoma (HCC), cause chronic inflammation that affects the brain through the liver-brain axis, leading to changes in neurotransmission and cognition. However, the impact of HCC on the hippocampus, a key brain region for learning and memory, is not well understood. Additionally, radiotherapy used to treat HCC can have severe side effects that negatively impact patients' quality of life. Therefore, it is crucial to design optimal strategies, such as chronotherapy, to improve the effectiveness and reduce the side effects of HCC treatment.
Article
Fisheries
Elham M. Ali, Naglaa Zanaty, Islam Abou El-Magd
Summary: This research uses remote sensing data and digital image processing techniques to monitor marine fisheries in Egypt. It has developed a model to determine optimal fishing zones for Sardinella aurita fisheries and detect similar zones for other economically important fish species. The study highlights the importance of using satellite data to develop sustainable management strategies for fisheries resources.
Correction
Oncology
Soha A. Hassan, Christian Schmithals, Maike von Harten, Albrecht Piiper, Horst-Werner Korf, Charlotte von Gall
INTERNATIONAL JOURNAL OF CANCER
(2022)
Article
Environmental Sciences
Hesham Kassem, Ehab Hassaneen, Alaa El-Din Sallam
CATRINA-THE INTERNATIONAL JOURNAL OF ENVIRONMENTAL SCIENCES
(2015)