4.7 Article

Hybrid mediated blood flow investigation for atherosclerotic bifurcated lesions with slip, convective and compliant wall impacts

Journal

Publisher

ELSEVIER IRELAND LTD
DOI: 10.1016/j.cmpb.2019.07.008

Keywords

Bifurcated artery; Slip effects; Blood flow; Atherosclerotic lesions; Convective boundary; Compliant walls; Hybrid nanoparticles

Funding

  1. higher education commission Pakistan [21-2464/SRGP/RD/HEC/2019]

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Objective: The present investigation is concerned with hybrid mediated blood flow model through atherosclerotic bifurcated artery with slip effects by considering the properties of compliant walls. Design/approach: In human body, the circulatory system is made up of a network of blood vessels that include the bifurcation therefore the influence of hybrid nanoparticles on parent artery with mild stenosis, at apex and in the region of daughter arteries (after being bifurcated) is observed. Blood streaming along the segment of vessel is considered to be Newtonian. The compliant nature of the atherosclerotic artery wall is also considered to create association with permeability aspects for the thickness of arterial wall. Property of heat transfer with convective impacts is taken into account to weaken the stenotic lesions. Through phase flow model approach, a mathematical model is develop with the phenomena of hybrid nanofluid. Findings: For theoretical research of designed equations experimentally determined values of nanoparticles and base fluid are used. Further, flow configurations of hemodynamics are figure out to analyze the blood flow through bifurcated stenotic artery. The comparison in parent and daughter artery is plotted for velocity profile. These patterns provide us a graphical way to recognize the importance of theoretical assistance of this model to biomedical field. At the end, it is concluded from graphical results that slip to the boundary reduces the resistance to flow for atherosclerotic bifurcated artery. Conclusions: In bifurcated artery, blood circulation is assumed due to difference of pressure between atherosclerotic and non-atherosclerotic portions. Slip impacts are more effective to reduce the hemodynamics effects of stenosis for bifurcated artery. Bifurcation angle reduces the shear stress for daughter artery whereas opposite behavior is observed for parent artery. Compliant wall parameters reduces the inner bolus size in stenotic region while number of bolus increases in bifurcated region. Reduction in the amplitude of shear stress for convective parameter is more prominent in the parent artery as compared to daughter artery. (C) 2019 Elsevier B.V. All rights reserved.

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