Cell therapy for central nervous system disorders: Current obstacles to progress

Electrical Stimulation Enhances Migratory Ability of Transplanted Bone Marrow Stromal Cells in a Rodent Ischemic Stroke Model

(2018) Jun Morimoto et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Stem cells and regenerative medicine for neural repair

(2018) Jun Takahashi   CURRENT OPINION IN BIOTECHNOLOGY

The Amelioration of Pain-related Behavior in Mice with Chronic Spinal Cord Injury Treated with Neural Stem/Progenitor Cell Transplantation Combined with Treadmill Training

(2018) Syoichi Tashiro et al.   JOURNAL OF NEUROTRAUMA

Autologous Induced Pluripotent Stem Cell-Derived Neurons to Treat Parkinson's Disease

(2018) Jeanne F. Loring   STEM CELLS AND DEVELOPMENT

Long-Term Potentiation Enhances Neuronal Differentiation in the Chronic Hypoperfusion Model of Rats

(2018) Hayato Takeuchi et al.   Frontiers in Aging Neuroscience

Cell encapsulation enhances antidepressant effect of the mesenchymal stem cells and counteracts depressive-like behavior of treatment-resistant depressed rats

(2018) Kyohei Kin et al.   MOLECULAR PSYCHIATRY

Best Practices for Translational Disease Modeling Using Human iPSC-Derived Neurons

(2018) Sandra J. Engle et al.   NEURON

An insight into non-integrative gene delivery approaches to generate transgene-free induced pluripotent stem cells

(2018) Krishna Kumar Haridhasapavalan et al.   GENE

Human iPS cell-derived dopaminergic neurons function in a primate Parkinson’s disease model

(2017) Tetsuhiro Kikuchi et al.   NATURE

Systemic administration of cell-free exosomes generated by human bone marrow derived mesenchymal stem cells cultured under 2D and 3D conditions improves functional recovery in rats after traumatic brain injury

(2017) Yanlu Zhang et al.   NEUROCHEMISTRY INTERNATIONAL

Human Neural Stem Cell Transplantation in Chronic Cervical Spinal Cord Injury: Functional Outcomes at 12 Months in a Phase II Clinical Trial

(2017) George M. Ghobrial et al.   NEUROSURGERY

Autologous Induced Stem-Cell–Derived Retinal Cells for Macular Degeneration

(2017) Michiko Mandai et al.   NEW ENGLAND JOURNAL OF MEDICINE

Growth factor therapy sequesters inflammation in affording neuroprotection in cerebrovascular diseases

(2016) Hung Nguyen et al.   Expert Review of Neurotherapeutics

Concise Review: Cell Therapies for Stroke and Traumatic Brain Injury: Targeting Microglia

(2016) Sean I. Savitz et al.   STEM CELLS

Fail-Safe Therapy by Gamma-Ray Irradiation Against Tumor Formation by Human-Induced Pluripotent Stem Cell-Derived Neural Progenitors

(2016) Mitsuko Katsukawa et al.   STEM CELLS AND DEVELOPMENT

Growth factor therapy sequesters inflammation in affording neuroprotection in cerebrovascular diseases

(2016) Hung Nguyen et al.   Expert Review of Neurotherapeutics

Increasing Dose of Autologous Bone Marrow Mononuclear Cells Transplantation Is Related to Stroke Outcome: Results from a Pooled Analysis of Two Clinical Trials

(2016) Francisco Moniche et al.   Stem Cells International

Transcriptional comparison of human induced and primary midbrain dopaminergic neurons

(2016) Ninuo Xia et al.   Scientific Reports

Endogenous neurogenesis following ischaemic brain injury: Insights for therapeutic strategies

(2014) Tobias D. Merson et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Developmental and degenerative modulation of brain-derived neurotrophic factor transcript variants in the mouse hippocampus

(2014) Jinwook Kim et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Intravenous Transplants of Human Adipose-Derived Stem Cell Protect the Brain from Traumatic Brain Injury-Induced Neurodegeneration and Motor and Cognitive Impairments: Cell Graft Biodistribution and Soluble Factors in Young and Aged Rats

(2014) N. Tajiri et al.   JOURNAL OF NEUROSCIENCE

Cognitive Symptom Management and Rehabilitation Therapy (CogSMART) for Veterans with traumatic brain injury: Pilot randomized controlled trial

(2014) Elizabeth W. Twamley et al.   JOURNAL OF REHABILITATION RESEARCH AND DEVELOPMENT

Reparative Therapy for Acute Ischemic Stroke with Allogeneic Mesenchymal Stem Cells from Adipose Tissue: A Safety Assessment

(2014) Exuperio Díez-Tejedor et al.   Journal of Stroke & Cerebrovascular Diseases

Participation After Multidisciplinary Rehabilitation for Moderate to Severe Traumatic Brain Injury in Adults: A Systematic Review

(2013) Michelle Brasure et al.   ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION

Factor structure of the Depression Anxiety Stress Scales in individuals with traumatic brain injury

(2013) Dana Wong et al.   BRAIN INJURY

Inhibition of CXCL12 Signaling Attenuates the Postischemic Immune Response and Improves Functional Recovery after Stroke

(2013) Karsten Ruscher et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Cotransplantation of human umbilical cord-derived mesenchymal stem cells and umbilical cord blood-derived CD34+ cells in a rabbit model of myocardial infarction

(2013) Tong Li et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Stem Cell Recruitment of Newly Formed Host Cells via a Successful Seduction? Filling the Gap between Neurogenic Niche and Injured Brain Site

(2013) Naoki Tajiri et al.   PLoS One

Neuroinflammation after traumatic brain injury: Opportunities for therapeutic intervention

(2012) Alok Kumar et al.   BRAIN BEHAVIOR AND IMMUNITY

Randomized controlled trials in adult traumatic brain injury

(2012) Juan Lu et al.   BRAIN INJURY

Clinical Achievements, Obstacles, Falsehoods, and Future Directions of Cell-Based Neurorestoratology

(2012) Hongyun Huang et al.   CELL TRANSPLANTATION

Hypoxic preconditioning enhances the therapeutic potential of the secretome from cultured human mesenchymal stem cells in experimental traumatic brain injury

(2012) Ching-Ping Chang et al.   CLINICAL SCIENCE

Treatment of Traumatic Brain Injury Using Zinc-Finger Protein Gene Therapy Targeting VEGF-A

(2012) Ishita Siddiq et al.   JOURNAL OF NEUROTRAUMA

Umbilical cord blood mononuclear cell transplantation for neonatal hypoxic–ischemic encephalopathy

(2012) Pedro M. Pimentel-Coelho et al.   PEDIATRIC RESEARCH

Activation of latent precursors in the hippocampus is dependent on long-term potentiation

(2012) M Kameda et al.   Translational Psychiatry

Assessment of Neuroprotective Effects of Human Umbilical Cord Blood Mononuclear Cell Subpopulations In Vitro and in Vivo

(2011) Johannes Boltze et al.   CELL TRANSPLANTATION

N-cadherin Determines Individual Variations in the Therapeutic Efficacy of Human Umbilical Cord Blood-derived Mesenchymal Stem Cells in a Rat Model of Myocardial Infarction

(2011) Eun Ju Lee et al.   MOLECULAR THERAPY

A more efficient method to generate integration-free human iPS cells

(2011) Keisuke Okita et al.   NATURE METHODS

Adult Neurogenesis in the Mammalian Brain: Significant Answers and Significant Questions

(2011) Guo-li Ming et al.   NEURON

Growth factors in ischemic stroke

(2010) S. Lanfranconi et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Direct conversion of fibroblasts to functional neurons by defined factors

(2010) Thomas Vierbuchen et al.   NATURE

The Impact of Levodopa on Quality of Life in Patients With Parkinson Disease

(2010) Kapil D. Sethi   NEUROLOGIST

The potential of neural stem cells to repair stroke-induced brain damage

(2009) Yi Ping Liu et al.   ACTA NEUROPATHOLOGICA

Exercise exerts neuroprotective effects on Parkinson's disease model of rats

(2009) Naoki Tajiri et al.   BRAIN RESEARCH

Stimulating neuroregeneration as a therapeutic drug approach for traumatic brain injury

(2009) Bernhard K Mueller et al.   BRITISH JOURNAL OF PHARMACOLOGY

Therapeutic Effects of Human Mesenchymal Stem Cells on Traumatic Brain Injury in Rats: Secretion of Neurotrophic Factors and Inhibition of Apoptosis

(2009) Hwa-Jung Kim et al.   JOURNAL OF NEUROTRAUMA

Electrical Stimulation of the Cerebral Cortex Exerts Antiapoptotic, Angiogenic, and Anti-Inflammatory Effects in Ischemic Stroke Rats Through Phosphoinositide 3-Kinase/Akt Signaling Pathway

(2009) Tanefumi Baba et al.   STROKE

Human Cord Blood Mononuclear Cells Decrease Cytokines and Inflammatory Cells in Acute Myocardial Infarction

(2008) Robert J. Henning et al.   STEM CELLS AND DEVELOPMENT