Review
Respiratory System
Jennifer D. D. Duke, Janani Reisenauer
Summary: Robotic bronchoscopy has advanced the detection and diagnosis of pulmonary nodules by providing improved navigation and maneuverability. This review highlights the technological advancements and future directions in the field of interventional pulmonary for the treatment of lung cancer through robotic bronchoscopy.
EXPERT REVIEW OF RESPIRATORY MEDICINE
(2023)
Review
Oncology
Samuel T. Freyaldenhoven, Hisashi Tsukada
Summary: The diagnosis of small lung lesions by electromagnetic navigational bronchoscopy is less effective compared to CT guided percutaneous transthoracic needle lung biopsy. Robotic bronchoscopy is a promising new technology that may revolutionize the diagnosis of small lung lesions. Real-time tools such as electromagnetic navigation, radial-endobronchial ultrasound, and cone beam CT have the potential to further improve the diagnostic yield rate.
JOURNAL OF SURGICAL ONCOLOGY
(2023)
Article
Oncology
Barak Pertzov, Evgeni Gershman, Shimon Izhakian, Moshe Heching, Shai Moshe Amor, Dror Rosengarten, Mordechai Reuven Kramer
Summary: This study evaluated the diagnostic yield and safety among patients undergoing peripheral pulmonary nodule biopsy with the LungVision system. The system showed good feasibility and safety, with a diagnostic yield of 81.8% overall and 72.2% for lesions smaller than 20 mm. Cryobiopsy with the system showed added diagnostic value, with malignant cells detected in tissue that was not found with other sampling tools. No major complications were reported, except for one patient who required chest tube treatment for pneumothorax.
Article
Surgery
Rachael Palumbo, Zoona Sarwar, Kenneth E. Stewart, Tabitha Garwe, J. Matthew Reinersman
Summary: This study explores the thoracic surgeon's experience in implementing an electromagnetic navigational bronchoscopy program for lung nodule evaluation. Factors such as nodule size, distance to the pleura, and bronchus sign were found to be important in successful navigation and diagnostic biopsy of nodules.
JOURNAL OF SURGICAL RESEARCH
(2022)
Review
Biology
Maxwell J. J. Diddams, Hans J. J. Lee
Summary: Robotic bronchoscopy (RB) improves access to smaller and peripheral lung lesions, while staging the mediastinum. However, the diagnostic yields in real-world RB studies have not fully matched pre-clinical findings. Nevertheless, RB technology has great potential for lung-cancer diagnosis and treatment. This article reviews the challenges with RB and compares three RB systems.
Article
Respiratory System
Bryan S. Benn, Arthur O. Romero, Mendy Lum, Ganesh Krishna
Summary: Robotic-assisted navigation bronchoscopy (RANB) combined with cone beam CT (CBCT) increases the sensitivity for malignancy and overall diagnostic accuracy of lung nodule biopsies, with a tissue diagnosis obtained in 83% of biopsied nodules, including 65% malignancies. Combining these modalities has the potential to shift the diagnostic approach to pulmonary nodules, with 85% sensitivity for malignancy and 86% diagnostic yield achieved.
Article
Oncology
Fawad Aleem Chaudry, Maureen Thivierge-Southidara, Juan Carlos Molina, Samid M. Farooqui, Syed Talal Hussain, Moishe Libermen
Summary: With the increasing incidence of finding lung nodules since the advent of lung cancer screening, this study compared the diagnostic accuracy and safety profile of two commonly used techniques: Electromagnetic navigational bronchoscopy (ENB) and CT-guided transthoracic needle aspiration (TTNA). The study found that CT-guided TTNA had a higher diagnostic accuracy but also a higher rate of complications compared to ENB.
Article
Critical Care Medicine
Or Kalchiem-Dekel, James G. Connolly, I-Hsin Lin, Bryan C. Husta, Prasad S. Adusumilli, Jason A. Beattie, Darren J. Buonocore, Joseph Dycoco, Paige Fuentes, David R. Jones, Robert P. Lee, Bernard J. Park, Gaetano Rocco, Mohit Chawla, Matthew J. Bott
Summary: This study provides comprehensive evidence on the feasibility and diagnostic yield of shape-sensing robotic-assisted bronchoscopy (ssRAB) in sampling pulmonary parenchymal lesions. ssRAB represents a significant advancement in accessing and sampling challenging lesions, while maintaining a high level of safety. Lesion size appears to be a major predictor for diagnostic procedures.
Review
Medicine, General & Internal
Abhishek Kumar, Jose D. Caceres, Siddharthan Vaithilingam, Gurshan Sandhu, Nikhil K. Meena
Summary: In recent years, advancements have been made in sampling of peripheral pulmonary lesions, but the diagnostic yield remains low. Current modalities have limitations, and a new robotic bronchoscopy technology aims to improve upon these aspects.
Article
Oncology
Yichen Zhang, Michael J. Simoff, David Ost, Oliver J. Wagner, James Lavin, Beth Nauman, Mei-Chin Hsieh, Xiao-Cheng Wu, Brian Pettiford, Lizheng Shi
Summary: This research analyzed the clinical pathway and characteristics of patients with lung cancer and solitary pulmonary nodules (SPN). The study found that the majority of lung cancer patients were in stages III or IV, and some SPN patients did not receive diagnostic work-up.
Article
Respiratory System
Christopher J. J. Manley, Tess Kramer, Rohit Kumar, Yulan Gong, Hormoz Ehya, Eric Ross, Peter I. I. Bonta, Jouke T. T. Annema
Summary: Robotic bronchoscopic needle-based confocal laser endomicroscopy (nCLE) is a feasible and safe technique that provides real-time feedback for optimizing needle positioning and diagnostic yield in small difficult-to-access lung nodules.
Article
Medicine, General & Internal
Chigozirim N. Ekeke, Matthew Vercauteren, Smiljana Istvaniczdravkovic, Roy Semaan, Rajeev Dhupar
Summary: Robotic-assisted bronchoscopy with ENB has shown a high diagnostic yield and safety in evaluating lung nodules, making it an important tool for the diagnosis of malignant or atypical nodules. Further studies with larger sample sizes are needed to better understand its clinical utility compared to other diagnostic tools for lung nodules.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Respiratory System
Catherine L. Oberg, Ryan P. Lau, Erik E. Folch, Tao He, Reza Ronaghi, Irawan Susanto, Colleen Channick, Rodrigo Garcia Tome, Scott Oh
Summary: Tissue acquisition in lung cancer is crucial for molecular testing, but insufficient amount of tumor cells and inadequate tissue quality often lead to diagnostic failure. This study demonstrates that the 1.1-mm cryoprobe, used in combination with robotic bronchoscopy, provides more diagnostic tissue compared to traditional methods. The cryoprobe's 360-degree tissue acquisition is particularly useful in targeting extraluminal lesions adjacent to the airway.
Article
Infectious Diseases
C-K Liam, P. Lee, C-J Yu, C. Bai, K. Yasufuku
Summary: Advancements in interventional pulmonology technologies have broadened the options for diagnosing and staging lung cancer, with procedures such as EBUS-TBNA, EUS-B-FNA, navigational bronchoscopy, and RP-EBUS available. The choice of sampling method should be based on factors such as tumor location, patient comorbidities, equipment availability, and local expertise to maximize diagnosis yield.
INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE
(2021)
Review
Respiratory System
Muhammad Sajawal Ali, Uzair Khan Ghori, Max Theodore Wayne, Eugene Shostak, Jose De Cardenas
Summary: Robotic-assisted bronchoscopy (RAB), utilizing shape-sensing and electromagnetic navigation-based platforms, has significantly improved the diagnostic yield of navigational bronchoscopy compared with conventional systems. However, further well-designed prospective studies are needed to explore the impact of factors such as three-dimensional imaging modalities, cryobiopsy, and specific ventilatory protocols on the diagnostic yield of RAB.
ANNALS OF THE AMERICAN THORACIC SOCIETY
(2023)