Review
Medicine, General & Internal
Sidar Copur, Furkan Yavuz, Alan A. Sag, Kathherine R. Tuttle, Mehmet Kanbay
Summary: Chronic kidney disease (CKD) is a common cause of death with an increasing trend, and there is currently no established approach for predicting CKD progression. Functional magnetic resonance imaging (fMRI) methods can assess kidney functions and predict the progression of CKD.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
(2022)
Review
Neurosciences
Armelle Viard, Francis Eustache, Shailendra Segobin
Summary: The history and evolution of magnetic resonance imaging have shaped a better understanding of memory systems and brain function, moving from simple imaging to complex analysis of brain structures and activity.
MRI technology has improved our ability to predict risks and detect subtle alterations in normal brain functioning, contributing to a deeper understanding of memory systems.
Article
Computer Science, Artificial Intelligence
Alexis Reymbaut, Alex Valcourt Caron, Guillaume Gilbert, Filip Szczepankiewicz, Markus Nilsson, Simon K. Warfield, Maxime Descoteaux, Benoit Scherrer
Summary: Diffusion tensor imaging provides increased sensitivity to microstructural tissue changes compared to conventional anatomical imaging, but presents limited specificity. To address this issue, the DIAMOND model subdivides voxel content into diffusion compartments and estimates compartmental non-central matrix-variate Gamma distributions of diffusion tensors. Incorporating tensor-valued diffusion encoding, the Magic DIAMOND model demonstrates improved accuracy in estimating brain microstructural features, particularly in regions of fiber crossing.
MEDICAL IMAGE ANALYSIS
(2021)
Article
Neurosciences
Yu Xiao, Ying Lin, Junji Ma, Jiehui Qian, Zijun Ke, Liangfang Li, Yangyang Yi, Jinbo Zhang, Cam-CAN, Zhengjia Dai
Summary: This study utilized multimodal neuroimaging and machine learning to investigate the neural mechanism of visual working memory in a large cohort of 547 individuals. The findings revealed significant predictors within specific neural networks for VWM and confirmed the specificity of these predictors compared to emotional regulation and fluid intelligence. The results provide a solid foundation for understanding cognitive functions with a multimodal approach.
HUMAN BRAIN MAPPING
(2021)
Article
Clinical Neurology
Bledi C. Brahimaj, Ryan B. Kochanski, John J. Pearce, Melike Guryildirim, Carter S. Gerard, Mehmet Kocak, Sepehr Sani, Richard W. Byrne
Summary: The goal of glioma surgery is to achieve maximal safe resection for optimal tumor control and survival benefits. Besides traditional MRI, multiple imaging modalities are utilized in preoperative evaluation to identify key functional areas, aiding in surgical planning and patient counseling.
Article
Clinical Neurology
Justin K. Zhang, Dinal Jayasekera, Chunyu Song, Jacob K. Greenberg, Saad Javeed, Christopher F. Dibble, Jacob Blum, Peng Sun, Sheng-Kwei Song, Wilson Z. Ray
Summary: This study evaluated the utility of diffusion basis spectrum imaging (DBSI) in cervical spondylotic myelopathy (CSM) and found that DBSI can serve as a biomarker of CSM disease severity. The results showed that DBSI provides detailed data on white matter tract integrity and offers novel insights into the pathology of CSM.
Article
Neurosciences
E. R. Sabidussi, S. Klein, B. Jeurissen, D. H. J. Poot
Summary: Diffusion weighted MRI is essential for patient screening and diagnosis. However, current deep learning methods for quantifying diffusion parameters lack generalization, requiring retraining for each new scan. In this study, we propose dtiRIM, a deep learning method for Diffusion Tensor Imaging with superior generalization due to its ability to solve inverse problems and promote data consistency using the diffusion tensor model. Results show that dtiRIM produces high-quality tensor estimates, comparable or better than existing methods, with low dependency on tissue properties and scanning parameters. Furthermore, a single dtiRIM model can be used for diverse datasets without significant loss in quality, making it a groundbreaking solution for DTI analysis.
Review
Cell Biology
Adam R. Bothwell, Susan M. Resnick, Luigi Ferrucci, Qu Tian
Summary: In aging, olfactory deficits have been associated with lower cognition and motor function. Olfactory dysfunction is also one of the earliest features of neurodegenerative disease. This review summarizes the relationship between brain structural and functional measures and olfaction in older adults, highlighting that lower olfactory function is associated with smaller volumes in specific brain areas important for motor function and cognition, especially memory. Future longitudinal studies with neuroimaging across different brain areas are needed to understand the neurobiological changes underlying olfactory changes in the aging brain and the progression of neurodegeneration.
AGEING RESEARCH REVIEWS
(2023)
Article
Health Care Sciences & Services
Niels Bergsland, Laura Pelizzari, Maria Marcella Lagana, Sonia Di Tella, Federica Rossetto, Raffaello Nemni, Mario Clerici, Francesca Baglio
Summary: This study demonstrates robust and clinically meaningful associations between substantia nigra microstructure and Parkinson's disease, particularly showing a significant correlation between axial diffusivity in SNpc and UPDRS III scores in PD patients.
JOURNAL OF PERSONALIZED MEDICINE
(2021)
Article
Biophysics
Franciszek Hennel, Eric Seth Michael, Klaas P. Pruessmann
Summary: The dependence of diffusion tensor on frequency is important in studying tissue microstructure, and oscillating gradient spin-echo sequences can be used to sample this dependence, improving measurement specificity by modifying waveforms.
NMR IN BIOMEDICINE
(2021)
Review
Radiology, Nuclear Medicine & Medical Imaging
Joon-Yong Jung, Yenpo Lin, John A. Carrino
Summary: Magnetic resonance neurography (MRN) is an increasingly used method to visualize peripheral nerves in vivo. However, it is challenging to implement and interpret MRN in the brachial and lumbosacral plexi due to anatomical complexity and technical limitations. This article reviews the clinical context of MRN, describes advanced magnetic resonance techniques for plexus imaging, and provides examples of MRN utility.
KOREAN JOURNAL OF RADIOLOGY
(2023)
Review
Clinical Neurology
Fabricio Guimaraes Goncalves, Angela N. Viaene, Arastoo Vossough
Summary: The soon-to-be-released 5th edition of the World Health Organization Classification of Tumors of the Central Nervous System is making extensive changes in the terminology regarding diffuse high-grade gliomas. Glioblastomas, as an entity, are now classified differently, with separate categories for pediatric and adult types. The standard care for pediatric glioblastomas is still uncertain, with surgery usually being the initial treatment option.
FRONTIERS IN NEUROLOGY
(2021)
Review
Medicine, General & Internal
Daryoush Shahbazi-Gahrouei, Fahimeh Aminolroayaei, Hamide Nematollahi, Mohammad Ghaderian, Sogand Shahbazi Gahrouei
Summary: This article reviews the characteristics of new MRI methods and discusses recent findings on breast cancer diagnosis. The findings suggest that diffusion-weighted imaging and diffusion tensor imaging can improve the specificity and accuracy of breast cancer diagnosis, leading to better treatment outcomes.
Article
Neurosciences
Autumn Horne, Junhua Ding, Tatiana T. Schnur, Randi C. Martin
Summary: Previous studies have found that there are different working memory buffers for maintaining phonological and semantic information. The phonological working memory buffer is located in the left supramarginal gyrus, while semantic working memory is related to the left inferior frontal gyrus, middle frontal gyrus, and angular gyrus. However, the white matter correlates of phonological and semantic working memory are not well understood. In this study, we tested individuals with left hemisphere brain damage on word processing and working memory tasks and found that different white matter tracts were associated with phonological and semantic working memory. This research provides valuable insights into the neural correlates of working memory and contributes to our understanding of the separate pathways supporting phonological and semantic working memory.
Article
Geriatrics & Gerontology
Stephanie Matijevic, Lee Ryan
Summary: The study found that age and sex have an impact on the cerebral white matter integrity of older adults, with a more significant effect on certain white matter tracts. Females exhibited lower global FA compared to males, but had higher MD in the anterior cingulum and superior longitudinal fasciculus. Age influenced both global FA and specific tract FA, while APOE epsilon 4 status did not show predictive power.
FRONTIERS IN AGING NEUROSCIENCE
(2021)
Article
Clinical Neurology
Piia Lonnberg, Elina Pihko, Leena Lauronen, Jussi Nurminen, Sture Andersson, Marjo Metsaranta, Aulikki Lano, Paivi Nevalainen
Summary: In extremely preterm born (EPB) children, absence of secondary somatosensory cortex (SII) response at term-equivalent age correlated with poorer motor outcome at age 6. However, there was no significant difference in SII responses between EPB and term-born (TB) children at age 6. Motor inhibition was associated with decreased SII peak latencies in TB children, but this effect was lacking in EPB children.
CLINICAL NEUROPHYSIOLOGY
(2021)
Article
Pediatrics
Krista Rantakari, Olli-Pekka Rinta-Koski, Marjo Metsaranta, Jaakko Hollmen, Simo Sarkka, Petri Rahkonen, Aulikki Lano, Leena Lauronen, Paivi Nevalainen, Markus J. Leskinen, Sture Andersson
Summary: The study suggests that both abnormally low and high oxygen levels during early NICU care are harmful for later neurodevelopmental outcomes in preterm infants. Specific brain structures seem to be vulnerable to low oxygen levels, while others are vulnerable to high oxygen levels. Strict saturation targets during the early postnatal period in preterm infants are emphasized for clinical implications.
PEDIATRIC RESEARCH
(2021)
Article
Psychology, Multidisciplinary
Leena Aho, Marjo Metsaranta, Piia Lonnberg, Elina Wolford, Aulikki Lano
Summary: This study found that neonatal neurobehavioral characteristics may serve as a precursor for later neurodevelopment and social cognition performance, with optimal auditory orientation and visual alertness at term age being associated with better developmental quotients and performance in various tests at different ages.
FRONTIERS IN PSYCHOLOGY
(2021)
Review
Pediatrics
Rachel Robinson, Polina Girchenko, Anna Pulakka, Kati Heinonen, Anna Lahdepuro, Marius Lahti-Pulkkinen, Petteri Hovi, Marjaana Tikanmaki, Peter Bartmann, Aulikki Lano, Lex W. Doyle, Peter J. Anderson, Jeanie L. Y. Cheong, Brian A. Darlow, Lianne J. Woodward, L. John Horwood, Marit S. Indredavik, Kari Anne Evensen, Neil Marlow, Samantha Johnson, Marina Goulart de Mendonca, Eero Kajantie, Dieter Wolke, Katri Raikkonen
Summary: This study examined the differences in ADHD symptoms and diagnosis between preterm and term-born adults and found that while preterm adults may not report higher levels of ADHD symptoms, they have a higher risk of receiving an ADHD diagnosis in adulthood.
PEDIATRIC RESEARCH
(2023)
Article
Multidisciplinary Sciences
Rachel K. Robinson, Kati Heinonen, Polina Girchenko, Marius Lahti-Pulkkinen, Eero Kajantie, Petteri Hovi, Aulikki Lano, Sture Andersson, Johan G. Eriksson, Dieter Wolke, Sakari Lemola, Katri Raikkonen
Summary: The study found that preterm and term born adults did not differ in optimism, but preterm individuals scored higher in pessimism. Additionally, preterm individuals with higher birth weight may have more optimistic life orientations.
Article
Sport Sciences
Jocelyn L. K. Tan, Anna-Mari Yla-Kojola, Johan G. Eriksson, Minna K. Salonen, Niko Wasenius, Nicolas H. Hart, Paola Chivers, Timo Rantalainen, Aulikki Lano, Harri Piitulainen
Summary: This study found that individuals at risk of Developmental Coordination Disorder (DCD) have lower levels of physical activity in adulthood. It also showed that those at risk of DCD spent more time in sedentary activities and less time in vigorous physical activity.
SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS
(2022)
Article
Medicine, General & Internal
Tuomas Kvist, Sara Sammallahti, Marius Lahti-Pulkkinen, Cristiana Cruceanu, Darina Czamara, Linda Dieckmann, Alina Tontsch, Simone Roh, Monika Rex-Haffner, Eiina Wolford, Rebecca Reynolds, Johan Eriksson, Sanna Suomalainen-Konig, Hannele Laivuori, Eero Kajantie, Eija Lahdensuo, Elisabeth Binder, Katri Raikkonen
Summary: The InTraUterine sampling in early pregnancy (ITU) is a prospective pregnancy cohort study that aims to unravel the mechanisms involved in the programming of health and disease after exposure to prenatal environmental adversity. It involves the collection of various biological samples and comprehensive phenotypic data from pregnant Finnish women and their partners and children.
Article
Psychology, Multidisciplinary
Ulla Niutanen, Piia Lonnberg, Elina Wolford, Marjo Metsaranta, Aulikki Lano
Summary: This study found that extremely preterm-born children performed inferiorly compared to term-born children across all assessments, with a wider variance and more co-occurring impairments. Multiple minor impairments accumulate among extremely preterm-born children at six years, suggesting the need for support and timely interventions throughout infancy and childhood.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Behavioral Sciences
Leena Aho, Viljami Sairanen, Piia Lonnberg, Elina Wolford, Aulikki Lano, Marjo Metsaranta
Summary: This study examines the relationship between early visual abilities, brain white matter structures, and later neurocognitive outcome. The results indicate that optimal visual alertness at term age is significantly associated with better visuospatial processing, sensorimotor functioning, and social perception at 6.5 years of age. Furthermore, the maturation of white matter structures and neurocognitive outcomes are positively correlated, suggesting that early visual function plays a crucial role in later neurocognitive development.
BRAIN AND BEHAVIOR
(2023)
Article
Pediatrics
Anu Haavisto, Liisa Klenberg, Viena Tommiska, Aulikki Lano, Kaija Mikkola, Vineta Fellman
Summary: The cognitive development trajectories of ELBW children vary, with significant decreases in intelligence scores by 11 years of age for those with average or below average intelligence at 5 years of age, while those with above average intelligence show stable development. Neonatal complications and maternal education level are important factors influencing subsequent intelligence development.
BMJ PAEDIATRICS OPEN
(2022)