Evaluating the molecule-based prediction of clinical drug responses in cancer

Improved large-scale prediction of growth inhibition patterns using the NCI60 cancer cell line panel

(2015) Isidro Cortés-Ciriano et al.   BIOINFORMATICS

In Silico Prescription of Anticancer Drugs to Cohorts of 28 Tumor Types Reveals Targeting Opportunities

(2015) Carlota Rubio-Perez et al.   CANCER CELL

Tumor-Derived Cell Lines as Molecular Models of Cancer Pharmacogenomics

(2015) A. Goodspeed et al.   MOLECULAR CANCER RESEARCH

Predicting clinical response to anticancer drugs using an ex vivo platform that captures tumour heterogeneity

(2015) Biswanath Majumder et al.   Nature Communications

A Phase I Dose Escalation and Expansion Study of the Anticancer Stem Cell Agent Demcizumab (Anti-DLL4) in Patients with Previously Treated Solid Tumors

(2014) D. C. Smith et al.   CLINICAL CANCER RESEARCH

Irresistible force meets immoveable object

(2014)   NATURE BIOTECHNOLOGY

Assessing the clinical utility of cancer genomic and proteomic data across tumor types

(2014) Yuan Yuan et al.   NATURE BIOTECHNOLOGY

MicroRNA-449a reduces cell survival and enhances cisplatin-induced cytotoxicity via downregulation of NOTCH1 in ovarian cancer cells

(2014) Yanqi Zhou et al.   TUMOR BIOLOGY

Systems biology of cisplatin resistance: past, present and future

(2014) L Galluzzi et al.   Cell Death & Disease

Clinical drug response can be predicted using baseline gene expression levels and in vitro drug sensitivity in cell lines

(2014) Paul Geeleher et al.   GENOME BIOLOGY

Precision Oncology: An Overview

(2013) Levi A. Garraway et al.   JOURNAL OF CLINICAL ONCOLOGY

Tumour heterogeneity in the clinic

(2013) Philippe L. Bedard et al.   NATURE

Mutational landscape and significance across 12 major cancer types

(2013) Cyriac Kandoth et al.   NATURE

Pan-cancer patterns of somatic copy number alteration

(2013) Travis I Zack et al.   NATURE GENETICS

The Cancer Genome Atlas Pan-Cancer analysis project

(2013) John N Weinstein et al.   NATURE GENETICS

MicroRNA-30c inhibits human breast tumour chemotherapy resistance by regulating TWF1 and IL-11

(2013) Jessica Bockhorn et al.   Nature Communications

Systematic identification of genomic markers of drug sensitivity in cancer cells

(2012) Mathew J. Garnett et al.   NATURE

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

(2012) Jordi Barretina et al.   NATURE

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Genomics and Drug Response

(2011) Liewei Wang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mir-30 reduction maintains self-renewal and inhibits apoptosis in breast tumor-initiating cells

(2010) F Yu et al.   ONCOGENE

New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1)

(2008) E.A. Eisenhauer et al.   EUROPEAN JOURNAL OF CANCER