Journal
BIOINFORMATICS
Volume 33, Issue 3, Pages 435-437Publisher
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btw634
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Funding
- MetaCentrum [LM2010005, AZV-MZ-CR 1634272A- 4/2016]
- CERIT-SC (CERIT Scientific Cloud) [CZ.1.05/3.2.00/08.0144]
- CEITEC [LQ1601]
- University of Guelph [051699]
- [MEYS-NPSI-LO1413]
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Motivation: The study of immunoglobulins and T cell receptors using next-generation sequencing has finally allowed exploring immune repertoires and responses in their immense variability and complexity. Unsurprisingly, their analysis and interpretation is a highly convoluted task. Results: We thus implemented ARResT/Interrogate, a web-based, interactive application. It can organize and filter large amounts of immunogenetic data by numerous criteria, calculate several relevant statistics, and present results in the form of multiple interconnected visualizations.
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