Article
Multidisciplinary Sciences
Woong Sik Jang, Da Hye Lim, Jung Yoon, Ahran Kim, Minsup Lim, Jeonghun Nam, Richard Yanagihara, Sook-Won Ryu, Bo Kyeung Jung, Nam-Hee Ryoo, Chae Seung Lim
Summary: In this study, three RT-LAMP primer sets were designed for detecting different genes of SARS CoV-2. It was found that the detection limits of two primer sets were low, showing comparable sensitivity to other widely used detection methods.
Article
Biotechnology & Applied Microbiology
Likui Zhang, Donghao Jiang, Qi Gan, Haoqiang Shi, Li Miao, Yong Gong, Philippe Oger
Summary: Tba UDG247 is a novel bifunctional glycosylase that can excise uracil from DNA and further cleave the phosphodiester bond of the generated AP site. Kinetic analyses show that the enzyme has a faster rate for uracil excision than for AP cleavage, suggesting that cleaving AP site is a rate-limiting step for its bifunctionality.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2021)
Article
Multidisciplinary Sciences
Yee Ling Lau, Ilyiana Binti Ismail, Nur Izati Binti Mustapa, Meng Yee Lai, Tuan Suhaila Tuan Soh, Afifah Haji Hassan, Kalaiarasu M. Peariasamy, Yee Leng Lee, Maria Kahar Bador Abdul Kahar, Jennifer Chong, Pik Pin Goh
Summary: RT-RPA is a rapid and accurate detection method for SARS-CoV-2, with a clinical sensitivity of 98% and specificity of 100%, proving to be a viable alternative to RT-qPCR.
Article
Biochemistry & Molecular Biology
Paul B. Orndorff, Arjan van der Vaart
Summary: Uracil damaged DNA largely follows trends in flexibility of undamaged DNA. The flexibility of DNA is increased by uracil, and U:G base paired strands are more flexible than U:A strands. Certain sequence contexts, especially the 3' base next to uracil, play a key role in DNA deformability.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
(2023)
Article
Chemistry, Analytical
Yayun Yang, Xiaoting Liu, Nan Zhang, Wei Jiang
Summary: In this study, a dumbbell probe-based triple cascade signal amplification strategy was proposed for sensitive and specific detection of UDG activity. The method significantly improved sensitivity, ensured specificity, and could also be used for inhibitor screening.
Article
Chemistry, Analytical
Guohua Qi, Chen Xu, Jiafeng Wang, Yu Tian, Bo Wang, Ying Zhang, Kongshuo Ma, Xingkang Diao, Yongdong Jin
Summary: This study presents a new technique for promoting cell differentiation through optoplasmonic method, which can significantly shorten cell differentiation time, enhance cellular bioenergetics levels, and potentially be applied in tissue repair and regeneration.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Xiaolei Song, Qin Ding, Juan Zhang, Rongli Sun, Lihong Yin, Wei Wei, Yuepu Pu, Songqin Liu
Summary: A smart catalyzed hairpin assembly (CHA) DNAzyme nanosystem has been developed for intracellular UDG imaging, utilizing MnO2 nanosheets as nanocarriers to efficiently deliver DNA probes into cells and promote the fluorescence resonance energy transfer response. This approach offers enhanced sensitivity for early-stage cancer prediction and diagnosis.
ANALYTICAL CHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Mai Wu, Tan Lin, Kunming Dong, Yong Gong, Xipeng Liu, Likui Zhang
Summary: This study characterizes a family IV uracil DNA glycosylase (Sis-UDGIV) from the hyperthermophilic crenarchaeon Sulfolobus islandicus REY15A and investigates the roles of nine conserved residues in uracil excision and four conserved cysteine residues in maintaining protein conformation and stability. The results provide insights into the biochemical function and DNA-binding specificity of archaeal family IV UDGs.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Analytical
Tong Zhang, Wei Zhao, Wang Zhao, Yuying Si, Nianzhen Chen, Xi Chen, Xinlian Zhang, Lieying Fan, Guodong Sui
Summary: A new CRISPR-LAMP technology has been developed for rapid and accurate diagnosis of respiratory tract viruses, with increased sensitivity and reduced aerosol contamination. The technology combines different techniques and designs to precisely diagnose pathogens and efficiently detect point mutations.
ANALYTICAL CHEMISTRY
(2021)
Article
Plant Sciences
Mieun Lee, Yu Been Heo, Han Min Woo
Summary: Base editing enables precise gene editing without donor DNA or double-stranded breaks. However, the uracil DNA glycosylase inhibitor (UGI) fused with the cytidine deaminase-Cas nickase cannot inhibit the archaic Type IV uracil DNA glycosylase in cyanobacteria. To overcome this limitation, dCas12a-assisted gene repression of the udg gene allowed base editing with high mutation frequencies in cyanobacteria.
Article
Chemistry, Analytical
Guozhen Tian, Wenting Li, Biao Liu, Meifang Xiao, Qianfeng Xia
Summary: We propose a novel electrochemical biosensing platform-based strategy for detecting abnormal expressions of uracil-DNA glycosylase (UDG). This method combines NiC-oP@PtCu nanozyme with multi-MNAzyme junctions to achieve ultrasensitive UDG detection. The biosensor is enzyme-free, exhibits a large dynamic range, and has potential applications in clinical diagnosis and biomedical research.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Biochemistry & Molecular Biology
Jing Li, Ye Yang, Chenyan Chang, Weiguo Cao
Summary: Uracil-DNA glycosylase (UDG) is an enzyme involved in base excision repair and mammalian demethylation. This study identifies a novel UDG enzyme that requires acidic conditions for its glycosylase activity. The study investigates the catalytic motifs and key residues of the enzyme and reveals its role in mutation prevention and stress resistance.
Article
Biochemistry & Molecular Biology
Ryan J. J. Buckley, Anna Lou-Hing, Karl M. M. Hanson, Nadia R. R. Ahmed, Christopher D. O. Cooper, Edward L. L. Bolt
Summary: DNA glycosylases play a crucial role in maintaining genetic fidelity during DNA replication by eliminating chemically damaged DNA bases that could lead to mutations. In this study, researchers identified Lhr protein in Escherichia coli as a uracil-DNA glycosylase that is independent of its DNA helicase activity. The deletion of the lhr gene in E. coli sensitized cells to oxidative stress and increased cytosine deamination to uracil. This suggests that Lhr protein functions in surveillance and removal of potentially mutagenic base changes during replication stress.
MOLECULAR MICROBIOLOGY
(2023)
Review
Chemistry, Analytical
Longxing Fan, Wentao Liu, Boning Yang, Yingchun Zhang, Xiaotao Liu, Xinglin Wu, Baoan Ning, Yuan Peng, Jialei Bai, Liangqia Guo
Summary: DNA glycosylase is a crucial enzyme for DNA damage repair, and its dysregulation can lead to dysfunction in base excision-repair. This study developed a multifunctional dsDNA probe mediated exponential rolling circle amplification (E-RCA) method for the simultaneous sensitive detection of hAAG and UDG, showing promising results for potential applications in detecting DNA glycosylase activities.
Article
Biophysics
Yi-Chen Du, Si-Yuan Wang, Ya-Xin Wang, Jia-Yi Ma, Dong-Xia Wang, An-Na Tang, De-Ming Kong
Summary: A highly sensitive biosensing strategy utilizing TdT and CRISPR-Cas12a for signal amplification was reported, showing great potential in the design of various biosensors and achieving ultrasensitive detection of UDG and T4 PNK. The biosensors developed based on this strategy display high sensitivity, signal amplification efficiency, and low background noise, making them promising for clinical diagnosis and biomedical research.
BIOSENSORS & BIOELECTRONICS
(2021)
Article
Chemistry, Analytical
Qiushu Du, Wenqi Wang, Xianghua Zeng, Xiliang Luo
Summary: An electrochemical biosensor based on an antifouling zwitterionic peptide hydrogel and poly (3,4-ethylenedioxythiophene) (PEDOT) was developed for accurate detection of prostate specific antigen (PSA) in complex human serum. The antifouling properties of the peptide hydrogel prevented nonspecific adsorption of proteins, cells, and other biomolecules, making it suitable for biosensing applications.
ANALYTICA CHIMICA ACTA
(2023)
Article
Chemistry, Analytical
Xiqin Yang, Min Chen, Zhanhua Zhang, Yang Li, Peipei Wang, Xiliang Luo, Shaoping Lv
Summary: This study proposes an effective strategy to construct low fouling electrochemical biosensors based on specially designed Aib-peptides. These Aib-peptides exhibit excellent antifouling properties and enhanced stability, enabling accurate and reliable detection of IgG in clinical human sera.
ANALYTICA CHIMICA ACTA
(2023)
Article
Chemistry, Analytical
Xuanhao Zhang, Qian Li, Qiqi Chao, Yuxi Zhang, Xufeng Sun, Gao-Chao Fan, Zhi Ling Song, Rongmei Kong, Xiliang Luo
Summary: In this study, a protein enzyme-free and general approach for sensitive detection of single nucleotide polymorphisms (SNPs) is developed using asymmetric MNAzyme probes. The multi-arm probe (MNAzyme-9M-13) with two asymmetric recognition arms is designed to detect EGFR T790 M mutation. Through a one-pot mixing, the probe enables the sensitive detection of the mutation without protein enzyme or multi-step operation. The strategy also shows potential for SNPs detection in long genomic sequences and short microRNAs.
ANALYTICA CHIMICA ACTA
(2023)
Article
Materials Science, Multidisciplinary
Nianzu Liu, Yihui Ma, Zhenying Xu, Yingshu Guo, Xiliang Luo
Summary: We report a PANI-HA hydrogel that combines rigid conducting polymer with flexible HA. The supramolecular assembly of PANI and HA via boronic acid bonds yields PANI-HA hydrogel with unique microstructure, electrical conductivity and hydrophilicity, showing excellent supercapacitor performance and electrochemical sensing for IgG. The PANI-HA hydrogel-based electrode exhibits high specific capacitance (369 F g(-1)) and good cycling stability (85% capacity retention after 1000 charge-discharge cycles). It can also be used as an electrochemical biosensor for IgG detection with good sensitivity, wide detection range, and low detection limit.
JOURNAL OF MATERIALS SCIENCE
(2023)
Article
Chemistry, Multidisciplinary
Lei Zhang, Han Liu, Qianyao Du, Guoqiang Zhang, Shanhui Zhu, Zhongtao Wu, Xiliang Luo
Summary: Photoresponsive phase change materials have the ability to store and release both photon and heat energy. By designing azobenzene surfactants at the molecular level, it is possible to achieve high gravimetric energy density and enhance molar isomerization enthalpy.
Article
Chemistry, Analytical
Xiqin Yang, Ping Chen, Xi Zhang, Hao Zhou, Zhen Song, Wenlong Yang, Xiliang Luo
Summary: A simple tactic for electrochemical determination of HER2, a typical biomarker for breast cancer, was developed through the construction of a low fouling sensing interface functionalized with PEG and peptide. The biosensor exhibited strong antifouling performances in complex biofluids due to the combined effect of PEG and peptide, and it had an ultralow limit of detection and a wide linear range for HER2 assay. The combination of PEG and peptide provided an effective strategy for the development of low fouling sensing platforms in complex biotic environments.
ANALYTICA CHIMICA ACTA
(2023)
Article
Chemistry, Analytical
Tingting Zhao, Jiaheng Shi, Junhao Wang, Yanyun Cui, Yifan Yang, Shenghao Xu, Xiliang Luo
Summary: Developing an endogenous stimuli-responsive and ultrasensitive DNA sensing platform that contains a logic gate biocomputation for precise cell subtype identification holds great potential for disease diagnosis and prognostic estimation.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Xiao-Long Zhang, Sha-Sha Li, Yi-Jia Liu, Wei-Wei Liu, Ling-Qi Kong, Ya-Qin Chai, Xi-Liang Luo, Ruo Yuan
Summary: An ingenious three-dimensional DNA walker with high walking efficiency is developed by limiting the reaction space, providing a rapid and sensitive detection method for miRNA. Compared to traditional DNA walkers, this immobilized DNA walker shows improved kinetic and thermodynamic favorability, resulting in faster reaction speed and higher walking efficiency. By utilizing this walker, a sensitive sensing platform for rapid miRNA-21 detection is constructed with a limit of detection of 19.8 aM, allowing for highly sensitive biomarker detection in cancer cell lysates.
ANALYTICAL CHEMISTRY
(2023)
Article
Biophysics
Yanxin Li, Shuju Zhao, Zhenying Xu, Xiujuan Qiao, Mingxuan Li, Youke Li, Xiliang Luo
Summary: A non-fouling electrochemical biosensor was constructed using antifouling peptides and electroneutral PNA as the recognizing probe for SARS-CoV-2 viral RNA. The biosensor exhibited remarkable sensitivity with a broad linear range (1.0 fM -1.0 nM) and a low detection limit of 0.38 fM. This study provided a new strategy for developing non-fouling sensing systems capable of detecting trace disease biomarkers in complex biological media.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Chemistry, Multidisciplinary
Zhen Song, Rong Li, Xiqin Yang, Adriano Ambrosi, Xiliang Luo
Summary: This paper presents a simple one-step assembly method for constructing phase-transited bovine serum albumin antifouling layers, which are used for the development of antifouling electrochemical sensors. These sensors can accurately and sensitively detect uric acid in human body fluids.
CHINESE CHEMICAL LETTERS
(2023)
Article
Chemistry, Analytical
Shuju Zhao, Zhen Song, Tao Liu, Xin Wang, Yanxin Li, Yaqun Xu, Hao Wang, Yumin Wu, Xiliang Luo
Summary: Zwitterionic peptides with strong water binding ability have been designed to construct antifouling biosensors with enhanced stability in complex biological fluids. The designed peptides demonstrated much stronger antifouling capability and significantly enhanced stability in human serum and blood. Furthermore, the biosensor integrating the designed antifouling peptide with CEA aptamer exhibited a great sensitivity for detecting CEA protein, making it promising for practical applications.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Chemistry, Physical
Nianzu Liu, Ruoxing Wang, Shengjie Gao, Ruifang Zhang, Fengru Fan, Yihui Ma, Xiliang Luo, Dong Ding, Wenzhuo Wu
Summary: Leveraging mechanically-induced piezoelectric polarization, piezocatalysis emerges as a viable mechanism for enhancing catalytic processes. Nanostructured, catalytically active, rationally designed piezo-electric semiconductors can achieve high-performance catalysts for various applications using cost-effective electrocatalytic pathways, such as mechanical stimuli. The facile synthesis of high-quality ZnO nanostructures enables low-cost, scalable manufacture and direct integration into electrocatalysts for enhanced performance.
Article
Chemistry, Analytical
Yaqun Xu, Xiujuan Qiao, Zhi-Ling Song, Gao-Chao Fan, Xiliang Luo
Summary: A robust photoelectrochemical (PEC) biosensor capable of accurate detection in human serum was developed by integrating a new engineered branching peptide (EBP) into a synergetic dual-photoelectrode system. The biosensor exhibited high sensitivity, specificity, and anti-interference properties.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Rui Han, Wenjie Hou, Yang Li, Min Chen, Caifeng Ding, Xiliang Luo
Summary: A sensitive electrochemical biosensor based on a self-designed cyclic peptide is capable of detecting the RBD antigen in human blood. The cyclic peptide possesses excellent antifouling properties and strong anti-enzymatic hydrolysis ability, making the biosensor stable and reliable for COVID-19 antigen testing.
SENSORS & DIAGNOSTICS
(2023)
Article
Biophysics
Ze Hu, Hao Wang, Huimin Chen, Gao-Chao Fan, Xiliang Luo
Summary: In this study, an ingenious approach of target-triggered cascade signal amplification in porous anodic aluminum oxide nanochannels was developed for ultrasensitive photoelectrochemical DNA bioanalysis. The innovative nanochannels PEC strategy launched a novel detecting platform for trace levels of DNA, providing a potential inspiration for other smart nanochannels PEC bioassays.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Biophysics
Reza Khodadadi, Manouchehr Eghbal, Hamideh Ofoghi, Alireza Balaei, Ali Tamayol, Karen Abrinia, Amir Sanati-Nezhad, Mohamadmahdi Samandari
Summary: This paper introduces an integrated portable centrifugal microfluidic system that automates cell and fluid manipulation for complete blood counting (CBC) analysis at the point-of-care (POC). The system utilizes a specially designed microfluidic disc for cell separation, solution metering and mixing, and cell counting, and is equipped with a custom script for automated quantification of cells. The proposed method shows a strong correlation with the gold standard hematology analyzer for various blood parameters. The portable system offers simplicity, affordability, and low power consumption, making it a potential solution for improving healthcare delivery in resource-limited settings and remote areas.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Nabil H. Bhuiyan, Joon S. Shim
Summary: Developing herd immunity is crucial for changing the course of the COVID-19 pandemic. An AI-driven point-of-care testing platform has been proposed for analyzing the body's response to SARS-CoV-2, and it has been successfully used for quantifying viral proteins and antibodies in blood samples. A data-receptive web-based dashboard system has also been developed for real-time analysis of herd immunity progress.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Alexiane Godain, Timothy M. Vogel, Pascal Fongarland, Naoufel Haddour
Summary: This study provides comprehensive insights into the intricate relationship between shear stress and electroactive biofilms in microbial fuel cells, highlighting the pivotal role of shear stress in influencing the growth kinetics, electrical performance, and physical structure of the biofilms. The study also emphasizes the complexities of extracellular electron transfer mechanisms and the need for complementary metaproteomic analyses.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Linjie Wang, Yixin Chen, Yang Ji, Shujun Zheng, Fei Wang, Caolong Li
Summary: A paper-based biosensor incorporating surface-enhanced Raman spectroscopy (SERS) and colorimetric detection has been developed for efficient quantification of intracellular glutathione (GSH). The biosensor exhibits excellent selectivity, stability, and precision, with low detection limits in both SERS and colorimetric modes. It has been successfully utilized for intracellular GSH detection and validated against a commercial GSH assay kit.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Quan Zhou, Jing Wang, Zhen Zhang, Alain Wuethrich, Richard J. Lobb, Matt Trau
Summary: This study presents a biosensor for sensitive detection of EMT-associated biomarkers on extracellular vesicles (EVs) surfaces during targeted therapy. Through longitudinal monitoring of patients, the biosensor shows its ability to identify the EMT-like phenotype switching on circulating EVs during the development of resistance.
BIOSENSORS & BIOELECTRONICS
(2024)
Review
Biophysics
Pratika Rai, Sabrina N. Hoba, Celine Buchmann, Robert J. Subirana-Slotos, Christian Kersten, Tanja Schirmeister, Kristina Endres, Bernd Bufe, Alexey Tarasov
Summary: Proteases have been proposed as potential biomarkers for various pathological conditions. The development of protease biosensors offers a more efficient way to investigate dysregulated proteases. This review article presents different optical and electrochemical detection methods for designing biosensors for all major protease families.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Chengxin Liu, Xu Shen, Li Yan, Runlian Qu, Yue Wang, Yaqin He, Zixuan Zhan, Piaopiao Chen, Feng Lin
Summary: In this study, a homogeneous rapid electrochemical aptasensor was developed to quantitatively detect CTCs in lung cancer patients. The aptasensor utilized a DNA nanosphere structure and a complementary aptamer to specifically detect mucin 1 as a marker for CTCs. The assay exhibited high specificity and sensitivity, and the results were consistent with other detection methods.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Danni Xue, Xing Dai, Jialong Zhao, Jiayao Zhang, Huan Liu, Kui Liu, Tao Xu, Chenjie Gu, Xingfei Zhou, Tao Jiang
Summary: In this study, a dual-enhancement SERS substrate based on Ti3C2TX and Ag nanocubes was fabricated for precise quantification of ritonavir and ibrutinib in serum. The formation of numerous electromagnetic hotspots between Ag nanocubes facilitated effective photo-induced charge transfer. The composite substrate showed excellent sensitivity, achieving low detection limits and high recoveries, making it promising for monitoring and identification of clinical blood drug concentration.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Tenghua Zhang, Zihui Xie, Xiaohe Zheng, Yuxin Liang, Yao Lu, Hankang Zhong, Feiyang Qian, Yuqing Zhu, Ruiting Sun, Yan Sheng, Jiaming Hu
Summary: This study reports a technology based on cationic lipid-polymer hybrid nanoparticles for efficient extracellular vesicle (EV) enrichment and in-situ detection of internal microRNAs. The technology demonstrates high EV enrichment efficiency and sensitive internal RNA detection, making it potentially useful for early pancreatic cancer diagnosis.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Wenjie Dai, Gaoxu Chen, Xiaoyan Wang, Shujun Zhen, Chengzhi Huang, Lei Zhan, Yuanfang Li
Summary: In this study, a novel metal organic gel (MOG) with dual electrochemiluminescence (ECL) properties was prepared by simple mixing. The MOG exhibited strong and stable anodic and cathodic ECL signals. By utilizing this MOG, an ECL resonance energy transfer (ECL-RET) biosensor was constructed for ultrasensitive detection of a specific gene. The study developed a straightforward technique for obtaining a single luminescent material with dual signals and expanded the analytical application of MOGs in the realm of ECL.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Lais Canniatti Brazaca, Amanda Hikari Imamura, Rodrigo Vieira Blasques, Jessica Rocha Camargo, Bruno Campos Janegitz, Emanuel Carrilho
Summary: The use of microfluidic paper-based analytical devices (muPADs) for medical diagnosis is a growing trend due to their low cost, easy use, simple manufacturing, and potential for application in low-resource settings. This review focuses on the advances in muPADs for medical diagnostics, discussing their use in detecting various biomarkers in common human biofluids. The challenges of biomarker detection in each sample are examined, along with innovative techniques to overcome these limitations. The commercialization difficulties of muPADs are also considered, along with future trends such as wearable devices and integrated platforms.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Minghong Jian, Xudong Sun, Hua Zhang, Xiaotong Li, Shasha Li, Zhenxin Wang
Summary: Matrix metalloproteinases (MMPs) are attractive biomarkers for cancer diagnosis and treatment, but their low abundance in biological samples, especially in the early stages of tumors, makes it challenging to precisely analyze MMP activities. In this study, a peptide microarray-based metal-enhanced fluorescence assay (PMMEFA) is proposed as a sensitive and specific method to simultaneously detect MMP-1, -2, -3, -7, -9, and -13 activities. The PMMEFA showed excellent sensitivity and was capable of detecting MMP activities in various matrices.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Kyung Ho Kim, Eunsu Ryu, Zinah Hilal Khaleel, Sung Eun Seo, Lina Kim, Yong Ho Kim, Hyun Gyu Park, Oh Seok Kwon
Summary: We have developed a novel strategy for discriminative detection of SARS-CoV-2 variants using the plasmonic photothermal effect of gold nanofilms and digital polymerase chain reaction (dPCR) technology. With this method, we were able to detect the delta and omicron variants with high sensitivity within 25 minutes from COVID-19 patients' clinical samples, making it a rapid and accurate point-of-care testing tool.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Zepeng Kang, Yuanming Wang, Haiyan Song, Xueli Wang, Job Zhang, Zhiguang Zhu
Summary: By designing a wearable and flexible lactic-acid/O2 EBFC with an air-breathing biocathode, the limitations of biocathode are effectively solved. The optimal performance conditions are determined through experiments, and the EBFC is successfully applied to power a low-power device.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Huayun Chen, Zhiheng You, Yuhui Hong, Xiao Wang, Mingming Zhao, Yushi Luan, Yibin Ying, Yixian Wang
Summary: This study developed a colorimetric sensor array using gas-responsive two-dimensional metal-organic framework (MOF) composites for highly sensitive detection of volatile organic compounds (VOCs). The dye/Zn-2(bim)(4) composites-based sensor arrays showed enhanced sensitivity and anti-interference properties. The findings demonstrate the potential use of dye/Zn-2(bim)(4) sensor arrays for early perception of plant diseases.
BIOSENSORS & BIOELECTRONICS
(2024)
