Single nucleotide polymorphisms linked to mitochondrial uncoupling protein genes UCP2 and UCP3 affect mitochondrial metabolism and healthy aging in female nonagenarians

Association ofUCP-3rs1626521 with obesity and stomach functions in humans

(2015) Andres Acosta et al.   Obesity

Functional interplay between MyoD and CTCF in regulating long-range chromatin interactions during differentiation

(2014) C. Battistelli et al.   JOURNAL OF CELL SCIENCE

The UCSC Genome Browser database: 2015 update

(2014) Kate R. Rosenbloom et al.   NUCLEIC ACIDS RESEARCH

UCP2 transports C4 metabolites out of mitochondria, regulating glucose and glutamine oxidation

(2014) A. Vozza et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Elevation of Resting Metabolic Rate With Declining Health in Nonagenarians May Be Associated With Decreased Muscle Mass and Function in Women and Men, Respectively

(2013) S. Kim et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Association of healthy aging with parental longevity

(2012) Sangkyu Kim et al.   AGE

Annotation of functional variation in personal genomes using RegulomeDB

(2012) A. P. Boyle et al.   GENOME RESEARCH

UCP3 polymorphisms, hand grip performance and survival at old age: Association analysis in two Danish middle aged and elderly cohorts

(2012) Serena Dato et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Uncoupling Protein-4 (UCP4) Increases ATP Supply by Interacting with Mitochondrial Complex II in Neuroblastoma Cells

(2012) Philip Wing-Lok Ho et al.   PLoS One

A common polymorphism in the UCP3 promoter influences hand grip strength in elderly people

(2011) Paolina Crocco et al.   BIOGERONTOLOGY

Four novel UCP3 gene variants associated with childhood obesity: effect on fatty acid oxidation and on prevention of triglyceride storage

(2011) C V Musa et al.   INTERNATIONAL JOURNAL OF OBESITY

CTCF Promotes Muscle Differentiation by Modulating the Activity of Myogenic Regulatory Factors

(2011) Paul Delgado-Olguín et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cellular Model of Warburg Effect Identifies Tumor Promoting Function of UCP2 in Breast Cancer and Its Suppression by Genipin

(2011) Vanniarajan Ayyasamy et al.   PLoS One

Further Support to the Uncoupling-to-Survive Theory: The Genetic Variation of Human UCP Genes Is Associated with Longevity

(2011) Giuseppina Rose et al.   PLoS One

HRAS1 and LASS1 with APOE are associated with human longevity and healthy aging

(2010) S. Michal Jazwinski et al.   AGING CELL

Genome-wide MyoD Binding in Skeletal Muscle Cells: A Potential for Broad Cellular Reprogramming

(2010) Yi Cao et al.   DEVELOPMENTAL CELL

Mitochondrial UCP5 is neuroprotective by preserving mitochondrial membrane potential, ATP levels, and reducing oxidative stress in MPP+ and dopamine toxicity

(2010) Ken Hon-Hung Kwok et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondrial uncoupling and lifespan

(2010) Shona A. Mookerjee et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Uncoupling protein-2 regulates lifespan in mice

(2009) Zane B. Andrews et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Mice Deficient in Both Mn Superoxide Dismutase and Glutathione Peroxidase-1 Have Increased Oxidative Damage and a Greater Incidence of Pathology but No Reduction in Longevity

(2009) Y. Zhang et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Genetic Variants in the UCP2-UCP3 Gene Cluster and Risk of Diabetes in the Women's Health Initiative Observational Study

(2008) Y.-H. Hsu et al.   DIABETES

Uncoupling protein-2 controls proliferation by promoting fatty acid oxidation and limiting glycolysis-derived pyruvate utilization

(2007) Claire Pecqueur et al.   FASEB JOURNAL